Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$100K - $120K *

Elevate quality standards by leading performance improvement initiatives, ensuring compliance with regulatory requirements, and fostering a culture of excellence in healthcare delivery across the orga...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead the charge in enhancing quality management initiatives, overseeing compliance and performance improvement activities within a skilled nursing facility, ensuring adherence to regulatory standards...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Champion operational excellence by managing administrative functions, recruiting, and onboarding for a growing inpatient practice. Collaborate with leadership to enhance staffing models and ensure com...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform healthcare operations by leading strategic initiatives, ensuring compliance, and driving quality improvements across multiple clinic sites. Collaborate with cross-functional teams to enhance...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $105K *

Elevate patient care by supporting the Clinical Director in enhancing services, leading staff training, and ensuring operational efficiency in a dynamic clinical environment. Join a progressive team d...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Join a team that's passionate about healthcare and mentorship! Lead clinic operations, cultivate community relationships, and enhance patient care through evidence-based practices while driving clinic...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $95K *

Shape the future of outpatient substance use treatment by blending hands-on clinical care with program leadership. Lead a dedicated team while establishing workflows and expanding community partnershi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$174K - $261K *

Transform healthcare delivery by leading clinical operations, ensuring integrated patient care, and fostering partnerships across community and hospital settings. Drive strategic initiatives and finan...

Kamloops, BCIn-Person

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$170K - $240K *

Drive excellence in Quality Assurance by overseeing the Quality Management System, ensuring compliance with global cGMP regulations, and fostering a high-performance culture to deliver transformative...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead multi-site clinical research operations, driving compliance, team development, and financial performance. Collaborate with C-suite to enhance participant safety and operational standards while fo...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Lead and develop a high-performing field Medical Affairs team, translating strategy into actionable objectives. Engage with healthcare professionals and stakeholders to drive scientific exchange and e...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Oversee the creation and management of the Clinical Management Office, ensuring strategic development of placement sites and compliance with regulations while leading projects and fostering relationsh...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Elevate your career by overseeing laboratory operations, vaccine programs, and clinical supply chains. Lead a team of medical assistants while ensuring compliance and efficiency across sites, contribu...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $96K *

Pioneer operational excellence by leading diverse teams and optimizing processes. Drive client-centered care through effective management of intake, billing, and technology systems while supporting gr...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of occupational health by providing strategic leadership and operational oversight. Collaborate with senior leaders to optimize services, enhance performance, and drive continuous imp...

Today

  •   5 - 7 years exp.  •   Healthcare

$179K - $205K *

Drive TMF operational excellence by leading strategy, oversight, and quality assurance across studies. Ensure inspection readiness and compliance while managing resources and metrics for continuous im...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$179K - $205K *

Transform TMF operations by leading strategic oversight, ensuring inspection readiness, and driving quality across studies. Collaborate with teams to enhance processes, manage resources, and uphold re...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$198K - $268K *

Drive the strategic vision for clinical research operations, ensuring alignment with institutional goals. Lead workforce development, enhance research infrastructure, and promote a culture of collabor...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $167K *

Elevate clinical excellence by leading regional teams to ensure high-quality patient care, driving quality improvement initiatives, and fostering a culture of safety and accountability across multiple...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the clinical services at a premier behavioral health facility, driving strategic planning and program development to enhance community care and meet performance goals in a supportive environment...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Unlock potential by leading operations for multiple Ambulatory Surgery Centers, driving growth strategies, optimizing performance, and fostering partnerships with physician leaders to enhance patient...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion operational excellence by leading nursing strategies that enhance patient care, optimize staffing, and improve throughput. Collaborate with diverse teams to implement evidence-based practices...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$225K - $325K *

Lead the charge in advancing innovative cell therapy programs by developing clinical strategies, protocols, and analyses while collaborating with diverse stakeholders to ensure successful trial execut...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dedicated team to enhance medical services, oversee staff, and ensure compliance with health standards while providing compassionate care to individuals in need...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform medical strategy by leading content development, analyzing clinical data, and mentoring teams. Collaborate with diverse stakeholders to drive client growth through innovative promotional ini...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.