Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$142K - $224K *

Engage with cross-functional teams to develop and execute market access strategies for oncology products, ensuring alignment with brand objectives and enhancing patient access through collaboration an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive growth by leading the global account management team to enhance post-sale customer experiences and maximize revenue through renewals and upsells, utilizing data-driven strategies and collaborati...

San Francisco, CARemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$133K - $204K *

Join a team that's redefining security operations by leading a dynamic Cyber Defense unit. You'll manage SOC performance, drive AI integration, and ensure effective incident response while mentoring e...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$125K - $150K *

Champion success in life sciences by driving enterprise solutions sales. Leverage industry connections to secure strategic partnerships and grow revenue across a diverse portfolio of clients, ensuring...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a team that's driving innovation in life sciences by executing strategic sales initiatives, building trusting relationships, and elevating client partnerships to expand our enterprise solutions f...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Deliver exceptional nursing services by managing a remote team, optimizing operations, and ensuring compliance with care standards. Partner with various stakeholders to enhance patient care and servic...

Ontario, CARemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Unlock potential by overseeing clinical trials, ensuring compliance with protocols and regulations. Collaborate with investigators and coordinators to protect participant rights and verify data integr...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join us to lead strategy and implementation for long-term services and supports, ensuring compliance and enhancing participant experience in a dynamic healthcare environment. Drive impactful partnersh...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$194K - $266K *

Lead the charge in driving commercial growth by securing high-value partnerships and expanding market presence. Mentor a dynamic team while executing strategic initiatives that enhance client relation...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$107K - $166K *

Transform healthcare engagement by connecting with HCPs through innovative digital and in-person strategies, enhancing patient care and experiences while collaborating with cross-functional teams to d...

Springdale, ARRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Lead the charge in patient engagement strategy, optimizing support programs and enhancing the patient journey from consideration to conversion. Collaborate across teams to amplify patient voices and d...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$107K - $166K *

Empower healthcare engagement by connecting with providers through innovative tools, enhancing patient care and experiences. Collaborate with cross-functional teams to drive insights and strategic dec...

Springfield, OHRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of product strategy by leading a high-performing team, driving innovation, and ensuring alignment across operations and technology to deliver exceptional customer value and measurable...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$144K - $288K *

Lead the charge in shaping strategic actuarial solutions for a dynamic healthcare portfolio. Drive team performance and collaboration to deliver impactful pricing and projections while navigating comp...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive impactful software delivery by managing engineering teams and vendor partnerships. Oversee backlog management, sprint execution, and cross-functional collaboration to ensure timely, quality rele...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Transform the future of regional marketing by leading strategic initiatives, optimizing brand performance, and fostering relationships with external experts to drive impactful marketing strategies in...

New York, NYRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $231K *

Innovate portfolio strategies by leveraging market insights and driving execution. Collaborate with cross-functional teams to enhance product offerings and achieve business objectives in the healthcar...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Champion strategic marketing initiatives and lead cross-functional teams to optimize brand performance in Immunology. Drive engagement with External Experts while managing regional marketing strategie...

New York, NYRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that's driving marketing transformation by leveraging Adobe's ecosystem. Lead consultative engagements, advise senior executives, and design integrated solutions that enhance client satisf...

New York, NYRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $200K *

Elevate client marketing strategies by leading transformative engagements using Adobe's ecosystem. Collaborate with senior executives to design data-driven solutions that enhance customer experiences...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$70K - $142K *

Lead the charge in enhancing academic operations and faculty performance, ensuring compliance with accreditation standards while fostering student success through strategic curriculum development and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $189K *

Lead the charge in developing and executing innovative marketing strategies for oncology products, collaborating with cross-functional teams to ensure successful launches and impactful customer engage...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in shaping product strategy and execution for a key applications portfolio, driving innovation and growth through AI integration while mentoring a high-performing team in a dynamic hea...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $159K *

Champion the development and execution of marketing strategies for ARIA core products, driving growth through market analysis, cross-functional collaboration, and innovative go-to-market initiatives t...

Atlanta, GARemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Shape high-impact growth in retail partnerships by overseeing field operations, driving application volume, and enhancing point-of-sale conversion rates. Collaborate with teams to optimize strategies...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.