Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $270K *

Drive the future of AI as you lead the engineering strategy for a cutting-edge platform. Collaborate across teams to design scalable, intelligent systems that enhance workflows and deliver impactful b...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Accelerate your career by driving new business growth and managing enterprise client relationships. Leverage your expertise in managed sales solutions to exceed targets and optimize sales processes in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$158K - $213K *

Oversee day-to-day accounting and treasury operations, ensuring accuracy and compliance. Lead month-end close processes, refine internal controls, and develop a high-performing team while integrating...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$184K - $249K *

Join a team that's driving innovative patient engagement and consumer marketing strategies within a vital oncology sector. Shape impactful programs by translating patient insights into strategic plans...

Thousand Oaks, CARemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Empower organizational growth by leading development initiatives that enhance team effectiveness, drive change, and align workforce capabilities with business objectives. Collaborate across functions...

Laval, QCRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $215K *

Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $200K *

Drive strategic growth and customer retention in enterprise accounts, fostering a high-performance culture. Lead initiatives to enhance partner satisfaction, generate revenue, and develop a skilled te...

New York, NYRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$116K *

Lead site activation efforts by coordinating with cross-functional teams to ensure timely and quality delivery of clinical projects. Drive strategic initiatives and mitigate risks while enhancing comm...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead and enhance People Operations by driving scalable service delivery, managing complex programs, and fostering a high-performing team to improve employee experience while ensuring compliance and op...

Lehi, UTRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $170K *

Join a team that's redefining production excellence by leading end-to-end photo and video shoots. You'll manage budgets, build partnerships, and create efficient workflows while ensuring brand integri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$248K - $373K *

Transform healthcare delivery by leading clinical reviews and benefit determinations. Collaborate with a multidisciplinary team to enhance member outcomes and ensure cost-effective care while working...

Minneapolis, MNRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $190K *

Lead the charge in advancing analytical development strategies for small molecule drug substances and products, ensuring compliance and quality across the product lifecycle while collaborating with cr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K *

Help us transform innovative ideas into life-saving solutions by leading business development efforts in the biotech and medtech sectors. Your expertise will drive client engagement and project succes...

San Francisco, CARemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $97K *

Shape the future of healthcare by conducting clinical case reviews and enhancing product quality for an AI-driven clinical platform. Collaborate with care teams to ensure accurate alert functionality...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Optimize the Go-To-Market operations by driving strategic initiatives, enhancing cross-functional collaboration, and ensuring accountability. Partner closely with leadership to streamline processes an...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate partner success by managing strategic mid-market and enterprise relationships. Drive revenue growth through effective onboarding, enablement, and co-selling, while collaborating cross-function...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Bring your expertise to drive revenue growth in healthcare through consultative sales and strategic partnerships. Own the full sales cycle, collaborate cross-functionally, and mentor future hires in a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$134K - $150K *

Lead the charge in optimizing customer onboarding by managing a team of implementation managers, ensuring seamless execution of over 500 concurrent projects while enhancing customer experience and ope...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $165K *

Lead transformative consulting engagements to enhance healthcare coding and middle revenue cycle processes, driving operational efficiency, compliance, and financial performance across diverse project...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$167K - $185K *

Shape your career by leading innovative digital marketing solutions within the pharmaceutical industry, focusing on HCP and patient engagement through a customer-centric lens and collaborating closely...

San Diego, CARemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Drive growth as an integral part of our Commercial Sales Team, managing key health system relationships and closing complex deals, while collaborating across departments and shaping the product roadma...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$139K - $201K *

Lead the charge in driving AI-assisted design practices across teams, managing program initiatives, and building roadmaps to ensure alignment and measurable outcomes in a dynamic, cross-functional env...

Denver, CORemote

Reposted today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$144K - $288K *

Drive strategic technology initiatives by leading program delivery and team development. Collaborate with cross-functional leaders to ensure financial discipline and measurable outcomes while fosterin...

Connecticut, USRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.