Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$172K - $290K *

Transform the marketing landscape by owning critical cross-functional projects. Drive initiatives from conception through execution, aligning teams around strategic goals while adapting to evolving bu...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $135K *

Champion revenue growth by building strategic customer relationships, driving sales through prospecting, expert consultations, and tailored proposals. Collaborate effectively to meet client needs and...

Atlanta, GARemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform operational excellence by leading a dynamic team to enhance client satisfaction, streamline processes, and drive continuous improvement across remote Central Operations. Collaborate with pee...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$85K - $125K *

Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform cloud infrastructure by leading strategy, team development, and automation. Drive security, reliability, and cost management while collaborating across functions to enhance operational excel...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $141K *

Lead cross-functional initiatives to optimize operational efficiency, budget planning, and resource allocation, fostering collaboration across business units to drive organizational goals and financia...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$192K - $260K *

Partner with us to transform R&D capabilities through innovative learning experiences, aligning workforce development with strategic priorities and enhancing employee performance across diverse functi...

CanadaRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in expanding staffing solutions across government sectors. Drive business development, operational excellence, and consultant delivery while ensuring scalable growth and profitability...

Indianapolis, INRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$225K - $295K *

Accelerate progress at the forefront of contract lifecycle management by driving innovation and strategic solutions. Collaborate with sales teams to enhance customer satisfaction and market leadership...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Lead optimization governance efforts to enhance clinical system effectiveness, improve clinician satisfaction, and implement process improvements through collaboration, analytic oversight, and perform...

South Carolina, USRemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $285K *

Advance regulatory strategies for global CMC submissions, managing cross-functional collaboration and internal processes to meet compliance with health authority standards, while leveraging strong com...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Help us lead client support for the RTSM application post-clinical study go-live. You'll manage sponsor communications, troubleshoot issues, and enhance system performance while ensuring a positive su...

Wellesley, MARemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Shape the future of oncology by leading biologics process development and manufacturing. Collaborate across teams to ensure compliance and quality in clinical-stage products, while mentoring scientist...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Engage in leading a dynamic team dedicated to delivering top-notch offensive security engagements, ensuring delivery quality and client satisfaction, while collaborating with sales to expand accounts...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$194K - $270K *

Shape the future of our strategic initiatives by leading high-impact projects that drive innovation and collaboration across teams. Partner closely with executive leadership to deliver measurable resu...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$235K - $270K *

Join a team that's driving access strategy across the Northeast, managing key payer relationships and ensuring launch readiness for rare disease therapies. Collaborate with cross-functional teams to o...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform the landscape of healthcare services by leading a national team, driving strategic initiatives, and ensuring compliance while enhancing patient admissions and marketing efforts across divers...

Concord, NHRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $200K *

Elevate your career by driving growth strategies within federal agencies, focusing on enhancing public services through innovative digital solutions. Leverage your expertise to build relationships and...

Washington, DCRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$116K - $174K *

Elevate regulatory strategies for global product approvals and compliance. Lead negotiations with authorities, manage complex projects, and drive innovative solutions to ensure successful market intro...

Illinois, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$195K - $325K *

Elevate the Risk & Compliance strategy for R&D, leading a team to foster a risk-aware culture, manage budgets, and engage with stakeholders to ensure effective cyber risk management across GSK's resea...

Philadelphia, PARemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize healthcare operations by analyzing equipment utilization, reducing unnecessary rentals, and driving impactful process improvements through data-driven insights and strong partnerships with cl...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Elevate patient support services by leading strategic operations and enhancing client partnerships. Drive innovation in HUB and affordability programs, ensuring compliance and excellence across divers...

Jeffersonville, INRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$261K - $367K *

Champion a culture of engagement and development, leading strategic initiatives across multiple regions to enhance veterinary services and client experiences while driving financial success and operat...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$105K - $150K *

The Senior Consultant, NetSuite is responsible for leading full-cycle NetSuite implementation projects, from discovery to deployment, while ensuring excellent customer service. This role involves coll...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.