Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Regional Sales Manager, Strategic
$110K - $130K *
Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...
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Director, Marketing Strategy and Operations
$172K - $290K *
Transform the marketing landscape by owning critical cross-functional projects. Drive initiatives from conception through execution, aligning teams around strategic goals while adapting to evolving bu...
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$120K - $135K *
Champion revenue growth by building strategic customer relationships, driving sales through prospecting, expert consultations, and tailored proposals. Collaborate effectively to meet client needs and...
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Manager, Central Operations Quality Support - Remote
$80K - $95K *
Transform operational excellence by leading a dynamic team to enhance client satisfaction, streamline processes, and drive continuous improvement across remote Central Operations. Collaborate with pee...
2 weeks ago
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
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$150K - $180K *
Transform cloud infrastructure by leading strategy, team development, and automation. Drive security, reliability, and cost management while collaborating across functions to enhance operational excel...
6 days ago
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$104K - $141K *
Lead cross-functional initiatives to optimize operational efficiency, budget planning, and resource allocation, fostering collaboration across business units to drive organizational goals and financia...
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$192K - $260K *
Partner with us to transform R&D capabilities through innovative learning experiences, aligning workforce development with strategic priorities and enhancing employee performance across diverse functi...
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Executive Director, Staffing Solutions
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Lead the charge in expanding staffing solutions across government sectors. Drive business development, operational excellence, and consultant delivery while ensuring scalable growth and profitability...
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Accelerate progress at the forefront of contract lifecycle management by driving innovation and strategic solutions. Collaborate with sales teams to enhance customer satisfaction and market leadership...
2 weeks ago
Process Owner, Clinical Optimization - Clinical Informatics/Information Solutions
$100K - $120K *
Lead optimization governance efforts to enhance clinical system effectiveness, improve clinician satisfaction, and implement process improvements through collaboration, analytic oversight, and perform...
4 weeks ago
AD/Director, Regulatory Affairs CMC
$190K - $285K *
Advance regulatory strategies for global CMC submissions, managing cross-functional collaboration and internal processes to meet compliance with health authority standards, while leveraging strong com...
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RTSM Study Project Lead - Level 1
$80K - $95K *
Help us lead client support for the RTSM application post-clinical study go-live. You'll manage sponsor communications, troubleshoot issues, and enhance system performance while ensuring a positive su...
1 week ago
Principal Scientist, Biologics
$150K - $180K *
Shape the future of oncology by leading biologics process development and manufacturing. Collaborate across teams to ensure compliance and quality in clinical-stage products, while mentoring scientist...
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Director of Services - US West
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$194K - $270K *
Shape the future of our strategic initiatives by leading high-impact projects that drive innovation and collaboration across teams. Partner closely with executive leadership to deliver measurable resu...
5 days ago
Director, Managed Markets - Regional - Northeast
$235K - $270K *
Join a team that's driving access strategy across the Northeast, managing key payer relationships and ensuring launch readiness for rare disease therapies. Collaborate with cross-functional teams to o...
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Senior Director Hospital and Patient Services
$150K - $180K *
Transform the landscape of healthcare services by leading a national team, driving strategic initiatives, and ensuring compliance while enhancing patient admissions and marketing efforts across divers...
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Director, Client Growth & Strategy, DHS
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Elevate your career by driving growth strategies within federal agencies, focusing on enhancing public services through innovative digital solutions. Leverage your expertise to build relationships and...
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Elevate regulatory strategies for global product approvals and compliance. Lead negotiations with authorities, manage complex projects, and drive innovative solutions to ensure successful market intro...
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Senior Director, Risk & Compliance Business Partners R&D
$195K - $325K *
Elevate the Risk & Compliance strategy for R&D, leading a team to foster a risk-aware culture, manage budgets, and engage with stakeholders to ensure effective cyber risk management across GSK's resea...
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$80K - $95K *
Optimize healthcare operations by analyzing equipment utilization, reducing unnecessary rentals, and driving impactful process improvements through data-driven insights and strong partnerships with cl...
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Vice President, Patient Services - Remote
$160K - $200K *
Elevate patient support services by leading strategic operations and enhancing client partnerships. Drive innovation in HUB and affordability programs, ensuring compliance and excellence across divers...
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Divisional Vice President, Field Operations East
$261K - $367K *
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$105K - $150K *
The Senior Consultant, NetSuite is responsible for leading full-cycle NetSuite implementation projects, from discovery to deployment, while ensuring excellent customer service. This role involves coll...
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What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.