Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
$91K - $179K *
Elevate your career by driving digital marketing strategies for diverse clients. Collaborate with teams to develop insights, optimize campaigns, and enhance performance metrics, ensuring impactful gro...
Today
$90K *
Lead the charge in overseeing nursing operations for individuals with intellectual and developmental disabilities, ensuring high-quality care and compliance with regulations while managing and trainin...
Today
Senior Director, Global Medical Affairs
$177K - $338K *
Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...
Reposted 2 weeks ago
Medical Director - Client Services and Analytics
$180K - $220K *
Lead the charge in transforming clinical sales strategies, enhancing client engagement, and driving market growth through innovative solutions and collaboration across teams to optimize healthcare del...
6 days ago
$140K - $185K *
Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...
Reposted 3 weeks ago
Practice Manager - Women's Midlife - Bethel Park - Full Time
$80K - $95K *
Manage daily operations of multiple physician practices, overseeing staff, budgets, and patient satisfaction. Collaborate with healthcare professionals to ensure compliance and improve quality metrics...
Reposted 1 week ago
Director of Sleep Medicine - Jefferson Einstein Philadelphia
$210K - $250K *
Join a dynamic team as you lead outpatient sleep services, combining patient care with operational oversight. Drive quality and accreditation while engaging in academic pursuits within a comprehensive...
3 days ago
Nurse Practitioner (PRN) - In-Home Health Assessments
$115K - $138K *
Drive comprehensive health assessments by collaborating with healthcare teams to enhance patient care and close care gaps. Utilize your expertise in adult and geriatric health to provide quality servi...
Yesterday
Nurse Practitioner (Skilled Nursing)
$110K - $125K *
Transform patient care by delivering high-quality, evidence-based medical services in a skilled nursing facility. Collaborate with an interdisciplinary team to enhance patient outcomes and ensure cont...
1 week ago
$75K - $90K *
Lead the charge in overseeing financial operations, ensuring compliance and exceptional service while managing billing, Medicaid processes, and team support in a dynamic healthcare environment...
2 weeks ago
General Pediatrics Physician Assistant or Nurse Practitioner in Orwigsburg
$90K - $110K *
Elevate pediatric care by joining a collaborative team focused on building meaningful relationships with patients and families while enjoying a flexible work-life balance in a supportive environment...
5 days ago
Vice President, Revenue Operations
$150K - $175K *
Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...
2 weeks ago
$104K - $156K *
Join us to architect innovative financial systems, leading greenfield projects that enhance data management and analytics. Collaborate across teams to implement your vision and drive impactful solutio...
Today
Senior Advisor, Clinical Science (remote)
$168K - $283K *
Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$153K - $268K *
Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...
2 weeks ago
$110K - $130K *
Lead the design and governance of master data frameworks to enhance planning processes across supply chain, procurement, and manufacturing. Collaborate with cross-functional teams to optimize inventor...
Reposted yesterday
$110K - $130K *
Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...
Today
$80K - $102K *
Contribute to the design of user-centric digital products across platforms, collaborating with cross-functional teams to create high-fidelity prototypes and workflows that enhance user experience and...
1 week ago
Behavioral Health Medical Director
$223K - $313K *
Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...
Reposted yesterday
People Systems and Solutions Manager
$188K - $235K *
Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...
2 weeks ago
Physician Assistant or Nurse Practitioner- Hybrid - Surgical Oncology
$95K - $115K *
Join a team that's dedicated to delivering exceptional specialty and critical care services. This role involves managing acute and chronic health conditions across diverse settings, ensuring high-qual...
Today
Staff Nurse Practitioner, Primary Care
$127K *
Contribute to transforming virtual primary care by delivering exceptional patient assessments, treatment plans, and ongoing support. Collaborate with healthcare teams while leveraging technology to en...
Reposted 3 weeks ago
Head of Legal / Deputy General Counsel
$150K - $180K *
Transform your career by leading the legal function for a pioneering foundation. You'll navigate complex IP, AI regulation, and nonprofit governance, ensuring compliance while fostering innovation and...
Today
Vice President of Product Management
$235K - $265K *
Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...
2 weeks ago
Senior Legal Counsel, Corporate & Commercial
$150K - $180K *
Innovate with us to build scalable legal frameworks that support rapid growth. As a strategic advisor, you'll manage complex agreements, corporate governance, and leverage AI to enhance operational ef...
1 week ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.