Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Dentist Jobs in Mississippi

Sort By: Relevance

$150K - $180K *

Join a team that's shaping the future of computer vision by leading our Delivery organization. You'll drive customer success, scale operations, and engage directly in complex implementations, ensuring...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$197K - $328K *

Shape the future of pharmacy network operations by leading a team of attorneys, providing strategic legal counsel on regulatory, operational, and transactional matters within the PBM landscape, while...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $185K *

Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$92K - $153K *

Shape the future of pediatric nursing by leading care delivery and fostering community relationships. Play a vital role in enhancing nursing practices and supporting staff development while ensuring q...

1 month ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $175K *

Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $156K *

Join us to architect innovative financial systems, leading greenfield projects that enhance data management and analytics. Collaborate across teams to implement your vision and drive impactful solutio...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$168K - $283K *

Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$153K - $268K *

Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $102K *

Contribute to the design of user-centric digital products across platforms, collaborating with cross-functional teams to create high-fidelity prototypes and workflows that enhance user experience and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$223K - $313K *

Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$188K - $235K *

Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$127K *

Contribute to transforming virtual primary care by delivering exceptional patient assessments, treatment plans, and ongoing support. Collaborate with healthcare teams while leveraging technology to en...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Transform your career by leading the legal function for a pioneering foundation. You'll navigate complex IP, AI regulation, and nonprofit governance, ensuring compliance while fostering innovation and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$235K - $265K *

Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Innovate with us to build scalable legal frameworks that support rapid growth. As a strategic advisor, you'll manage complex agreements, corporate governance, and leverage AI to enhance operational ef...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $155K *

Empower teams to elevate product design through strategic vision, fostering collaboration across disciplines to create impactful digital experiences that meet user needs and business goals while ensur...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Shape the future of our commercial launch by leading a regional sales team to drive market entry, foster customer relations, and exceed performance goals in a dynamic, cross-functional environment...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $158K *

Shape the future of Medicaid wellness by leading innovative strategies and solutions that enhance health outcomes for underserved populations. Collaborate with diverse teams to develop impactful progr...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.