Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$210K - $260K *

Transform the workplace culture and integration of two organizations, ensuring support for clinicians and staff while enhancing benefits, compensation, and recruitment strategies to foster a unified m...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $232K *

Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team to enhance website performance and user experience through innovative SEO strategies, technical audits, and content optimization, driving organic visibility and business results on...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $133K *

Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock your potential by delivering exceptional primary eye care with a supportive team. Focus on personalized patient experiences while enjoying opportunities for professional growth and a positive...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Join a dedicated team to deliver exceptional primary eye care, focusing on personalized patient experiences. Enjoy the freedom to practice your interests while fostering a compassionate, patient-first...

3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Join a team that's dedicated to providing exceptional urgent and primary care. Utilize your skills to diagnose, treat, and develop care plans for patients of all ages while collaborating with clinical...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in enhancing operational efficiency by addressing performance gaps, implementing sustainable solutions, and fostering collaboration across departments to drive results and support long...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $140K *

Innovate within the healthcare sector by identifying market gaps and designing impactful products. Collaborate across teams to drive product strategy, ensuring solutions meet industry needs while enha...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$302K - $483K *

Transform the future of secure platforms by leading engineering strategy and execution. Drive innovation, operational excellence, and team performance to empower autonomy and accountability across the...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Advance your career by ensuring safe medication practices and enhancing patient care. Collaborate with healthcare professionals to review prescriptions, resolve drug-related issues, and provide except...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$83K - $112K *

Partner with us to navigate complex patient cases and ensure seamless access to care. Utilize critical thinking and communication skills to manage authorizations and appeals, collaborating with divers...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of surgical care by leading a dedicated team, fostering collaboration, and ensuring high-quality patient outcomes while managing departmental resources and compliance with regulations...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead the charge in managing contracts for utility-scale solar and infrastructure projects. Collaborate with cross-functional teams to ensure compliance, streamline documentation, and support project c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $110K *

Manage comprehensive evaluations and treatment plans for chronic pain patients, collaborating with healthcare teams to enhance patient outcomes and quality of life through evidence-based practices and...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Champion full-cycle physician recruitment by partnering with leaders to enhance candidate experiences and build talent pipelines, driving organizational growth through strategic workforce planning and...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K *

Empower clients by managing complex care needs through remote case management, ensuring access to high-quality treatment and support. Collaborate with multidisciplinary teams to enhance client engagem...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $160K *

Join a dynamic team of engineers to develop innovative software solutions, enhance user experiences, and drive impactful projects. Collaborate across functions while embracing modern technologies and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$143K - $196K *

Lead global evidence strategy and drive scientific engagement while collaborating cross-functionally to identify evidence gaps and shape priorities in clinical, R&D, and marketing teams. Make a signif...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower individuals by providing comprehensive psychological assessments and treatment plans. Collaborate with a multidisciplinary team to enhance patient care and contribute to operational excellence...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$230K - $250K *

Lead the charge in shaping a premium brand vision while driving creative strategy and operational excellence in a high-growth environment. Collaborate with cross-functional teams to elevate brand iden...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Transform your career by leading AI initiatives that drive business growth and operational efficiency. Collaborate across functions to embed AI into Rho's core operations, shaping a future where AI en...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.