Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
$110K - $130K *
Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...
3 weeks ago
$130K - $160K *
Innovate as a dynamic leader, driving clinical excellence and operational growth in a healthcare facility. Foster physician partnerships, enhance patient care quality, and lead high-performing teams w...
Reposted 2 weeks ago
Manager, Clinical Data Acquisition
$73K - $130K *
Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...
3 weeks ago
Account Specialist (Athens, GA)
$160K - $192K *
Drive commercial success by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and enhance patient access to innovative th...
5 days ago
$80K - $90K *
Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...
Reposted 2 weeks ago
Analyst - Information Technology
$66K - $113K *
Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...
4 weeks ago
$148K - $185K *
Join us to create user-centered designs that enhance account opening experiences for banks and credit unions, collaborating closely across teams to innovate and uphold a high standard of quality and c...
Reposted 1 week ago
$160K - $200K *
Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...
1 week ago
$110K - $160K *
Lead the charge in driving growth and strategy for our largest pro partners by leveraging data insights. Manage cross-functional projects to shape impactful initiatives, build frameworks, and measure...
Reposted 4 weeks ago
$150K - $180K *
Join a team that's shaping the future of computer vision by leading our Delivery organization. You'll drive customer success, scale operations, and engage directly in complex implementations, ensuring...
3 weeks ago
Senior Managing Counsel-Pharmacy Network Operations
$197K - $328K *
Shape the future of pharmacy network operations by leading a team of attorneys, providing strategic legal counsel on regulatory, operational, and transactional matters within the PBM landscape, while...
Reposted 6 days ago
Account Specialist (Peachtree City, GA)
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
5 days ago
$80K - $95K *
Transform nursing services by leading a dedicated team to ensure high-quality care in compliance with regulations. Drive operational excellence and foster a compassionate environment for both long-ter...
3 days ago
Senior Director, Global Medical Affairs
$177K - $338K *
Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...
Reposted 2 weeks ago
$140K - $185K *
Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...
Reposted 3 weeks ago
PHYSICIAN ASSISTANT - PRIMARY MEDICINE ASSOCIATES SMITHS STA
$85K - $100K *
Shape the future of patient care by delivering comprehensive assessments, implementing care plans, and collaborating with healthcare teams to ensure optimal outcomes and safety for all patients. Join...
Reposted today
Vice President, Revenue Operations
$150K - $175K *
Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...
2 weeks ago
$104K - $156K *
Join us to architect innovative financial systems, leading greenfield projects that enhance data management and analytics. Collaborate across teams to implement your vision and drive impactful solutio...
Today
Senior Advisor, Clinical Science (remote)
$168K - $283K *
Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$153K - $268K *
Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...
2 weeks ago
$110K - $130K *
Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...
Yesterday
$80K - $102K *
Contribute to the design of user-centric digital products across platforms, collaborating with cross-functional teams to create high-fidelity prototypes and workflows that enhance user experience and...
1 week ago
Behavioral Health Medical Director
$223K - $313K *
Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...
Reposted yesterday
People Systems and Solutions Manager
$188K - $235K *
Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...
2 weeks ago
Head of Legal / Deputy General Counsel
$150K - $180K *
Transform your career by leading the legal function for a pioneering foundation. You'll navigate complex IP, AI regulation, and nonprofit governance, ensuring compliance while fostering innovation and...
Yesterday
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.