Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$83K - $93K *

Lead clinical care initiatives by managing complex patient needs, coordinating with multidisciplinary teams, and enhancing care quality. Drive patient engagement and support health goals while fosteri...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower a dedicated clinical team to deliver exceptional patient care while overseeing operations, compliance, and staff development. Drive quality improvement initiatives and strategic planning to en...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion operational excellence by overseeing Laboratory, Pharmacy, and Diagnostic Bio-Med services. Collaborate with leadership to ensure compliance, enhance service delivery, and drive departmental...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Transform the future of clinical laboratory testing by overseeing Point of Care Testing operations, ensuring compliance, quality assurance, and staff training while collaborating with medical leadersh...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in enhancing quality improvement initiatives, ensuring compliance and operational excellence across behavioral health services. Collaborate with leadership to foster a culture of accou...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$92K - $127K *

Grow your career with a dynamic team as you guide clinical practice, ensure quality care, and empower patients in a home health setting. Collaborate with clinicians to enhance service delivery and ach...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Empower nursing excellence by directing patient care regimens, guiding staff, and collaborating with interdisciplinary teams to enhance health outcomes and ensure quality nursing practices within the...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in enhancing operational efficiency and patient access to specialty therapies, focusing on team development and exceptional care delivery in a dynamic healthcare environment...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Elevate patient care by leading nursing teams in developing and implementing effective care regimens. Collaborate with interdisciplinary teams to enhance health outcomes while ensuring compliance with...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Transform the health sector by leading strategic growth initiatives, nurturing client relationships, and driving impactful projects. Elevate brand reputation through innovative design and exceptional...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$284K - $385K *

Shape the future of clinical research by leading innovative trials in cardiology and nephrology. Collaborate with cross-functional teams to ensure patient safety and drive impactful study designs that...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Manage operational leadership for Care Coordination, overseeing staff, workflows, and patient advocacy. Collaborate with interdisciplinary teams to enhance care progression, resource utilization, and...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$333K - $416K *

Advance global clinical development efforts for neuropsychiatric disorders, overseeing study design, execution, and interpretation. Build relationships within the medical community and ensure complian...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$333K - $416K *

Engineer and lead clinical development plans for neuropsychiatric disorders. Drive the execution of clinical studies and foster relationships with key stakeholders while ensuring compliance with regul...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$333K - $416K *

Join a team that's committed to advancing clinical development for neuropsychiatric disorders and rare diseases. Contribute your extensive clinical expertise, develop robust study plans, and foster re...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $172K *

Advance critical care services by providing strategic leadership and fostering team growth. Oversee departmental operations, ensure high-quality patient care, and drive quality improvement initiatives...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform patient care by leading dialysis operations across multiple facilities. Collaborate with nursing teams to ensure compliance, quality outcomes, and staff development while providing clinical...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$70K - $99K *

Support clinic operations by ensuring compliance, fostering community ties, and managing resources. Lead quality care initiatives and maintain financial integrity while coaching staff and enhancing pa...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Elevate your career by leading enterprise-wide analytics and decision support. Collaborate with cross-functional leaders to enhance financial planning, operational effectiveness, and strategic insight...

4 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$135K - $160K *

Lead the charge in architecting and implementing complex application solutions, ensuring seamless integration and alignment with enterprise standards while driving enhancements and supporting technica...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $160K *

Drive the integration of complex application solutions, collaborating with cross-functional teams to enhance efficiency and resolve issues, while providing expert guidance in a consultative role to en...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $95K *

Manage and oversee clinical support teams, ensuring adherence to policies, optimizing training outcomes, and maintaining high-quality client care while fostering effective communication across departm...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$247K - $322K *

Lead the charge in advancing clinical operations for late-stage cardiovascular studies. Oversee cross-functional teams, manage budgets, and drive innovative strategies to enhance patient outcomes and...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$275K - $293K *

Drive strategic initiatives and operational excellence as a key partner to the CEO, optimizing internal processes and supporting growth in the neurological care sector. Collaborate across teams to enh...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.