Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$110K - $130K *
Unlock growth by driving revenue from top-tier accounts while nurturing leads. Collaborate with Sales leadership to shape strategy and establish expertise in digital transformation for financial insti...
3 days ago
Data Center Operations System Engineer - Plano, TX
$95K - $115K *
Advance your career by ensuring optimal performance of critical data center infrastructure. Collaborate with teams to troubleshoot, document, and manage hardware and software systems in a fast-paced e...
3 days ago
Solution Architect, Legal Billing
$130K - $145K *
Help us design and implement billing solutions for law firms, leveraging your accounting expertise and software skills to streamline time entry, invoicing, and collections processes on the Litify plat...
3 days ago
$125K - $140K *
Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...
3 days ago
Associate Claims Manager - Dental/Medmal
$120K - $160K *
Lead the charge in transforming claims management by leveraging your expertise to drive data-informed decisions, enhance processes, and foster collaboration across teams, ensuring exceptional service...
3 days ago
Channel Account Manager, DIB/MSSP
$215K - $235K *
Lead the charge in building a robust partner ecosystem for defense contractors, driving revenue through MSSPs, MSPs, RPOs, and C3PAOs. Own partner recruitment, enablement, and success, while collabora...
3 days ago
Account Executive, Commercial West
$300K - $350K *
Lead the charge in driving enterprise revenue across the West territory, engaging with senior security leaders in regulated industries. Shape strategic sales initiatives and build lasting relationship...
3 days ago
Software Development Test Engineer (SDET), KSM
$110K - $130K *
Join a team that's shaping the future of cybersecurity by designing and scaling automated test systems for a leading secrets management platform, ensuring quality and reliability in cloud-native servi...
3 days ago
Director, Channel Sales - Software
$150K - $180K *
Drive the creation of a unified global partner program for software sales, assessing regional strategies and building a scalable model that enhances partner engagement and revenue across multiple regi...
3 days ago
Product Development & Marketing Manager
$120K - $130K *
Partner with us to drive product innovation and marketing strategies across dietary supplements and topical hair care. Collaborate with cross-functional teams to launch new products, ensuring alignmen...
3 days ago
Clinical Application Specialist, Monitoring
$90K *
Elevate your career by providing clinical support and training for patient monitoring systems. Lead implementation teams, ensure customer satisfaction, and maintain clinical expertise while managing t...
3 days ago
Clinical Marketing Manager, Patient Monitoring
$130K - $143K *
Optimize your career by developing and executing clinical marketing strategies that enhance customer engagement and drive adoption of innovative patient monitoring solutions. Collaborate with cross-fu...
3 days ago
$82K - $108K *
Grow your career with a dynamic role driving strategic growth in wholesale and government sales. Lead account management, cultivate partnerships, and enhance market presence while collaborating cross...
3 days ago
Manager, Product Management - Content Management Systems
$128K - $178K *
Lead the evolution of our CMS and AI web strategy, driving product vision and execution for public sector clients. Collaborate with cross-functional teams to deliver innovative, customer-focused solut...
3 days ago
Virtual Design Construction Designer
$68K - $93K *
Unlock potential by spearheading designs and strategies through collaboration and innovation. Work alongside teams and clients to deliver cutting-edge solutions in electrical and automation sectors wh...
Reposted 3 days ago
$128K - $170K *
Optimize financial strategies and drive growth initiatives as a trusted advisor to leadership. Engage in M&A analysis, pricing strategy, and market insights to enhance decision-making in a dynamic Saa...
3 days ago
Strategy and Operations Physician Enterprise Clinical SME
$125K - $235K *
Drive operational excellence in healthcare by leading transformative initiatives, optimizing workflows, and enhancing provider productivity. Collaborate with teams to deliver data-driven solutions tha...
3 days ago
$139K - $179K *
Develop and execute impactful marketing campaigns that enhance brand awareness and drive pipeline growth in the AMERs region. Collaborate with cross-functional teams to optimize strategies and ensure...
3 days ago
$115K - $140K *
Help us drive success by coordinating bid opportunities across defense and commercial sectors. You'll manage the entire proposal process, ensuring compliance and collaboration among cross-functional t...
3 days ago
Facilities Assessment Consultant - Mechanical (East, US)
$70K - $117K *
Unlock potential by conducting comprehensive assessments of mechanical systems across diverse facilities. Collaborate with clients, document findings, and develop cost estimates while ensuring complia...
3 days ago
Principal Product Manager- Activation
$190K - $210K *
Transform the owner activation journey by streamlining processes from agreement to live listing. Drive metrics on activation rates and retention while collaborating with teams to enhance onboarding ef...
3 days ago
Talent Development & Community Program Manager
$125K - $135K *
Discover your potential by designing a unified learning and culture experience. Lead talent development initiatives, onboarding, and community programs to foster connection and growth within a dynamic...
3 days ago
Senior Software Engineer, Consumer
$159K - $254K *
Transform the digital dining experience by leading full-stack development efforts, collaborating with cross-functional teams to innovate and enhance guest interactions through cutting-edge web solutio...
3 days ago
$100K - $120K *
Transform client engagement by leveraging Instructure products to enhance learning outcomes. Collaborate with stakeholders to implement best practices, drive adoption, and support educational initiati...
3 days ago
Senior Structural Engineer-Bridge
$88K - $154K *
Join a team that's redefining bridge engineering by delivering innovative designs and solutions. Collaborate on diverse projects, ensuring structural reliability and efficiency while enhancing your ex...
3 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.