Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$135K - $160K *

Pioneer product storytelling and market launch strategies using AI tools to drive competitive positioning and sales enablement. Take ownership of the product marketing function and influence across te...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $149K *

Drive innovation and strategic initiatives while leading cross-functional teams to achieve impactful outcomes in a dynamic environment. Collaborate with diverse stakeholders to enhance operational eff...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Drive strategic compensation initiatives and provide expert guidance to leaders on pay practices, influencing global programs and promoting equity while evolving structures to enhance organizational g...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in AI and Machine Learning innovation, designing and deploying transformative models to enhance user experience, drive business growth, and improve operational efficiency collaborative...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Shape the future of our product experiences by building high-impact frontend features. Collaborate with cross-functional teams to deliver maintainable, efficient code using modern frameworks in a dyna...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$72K - $113K *

Deliver impactful insights by owning our marketing tech ecosystem, maximizing HubSpot and Salesforce integration, and ensuring data integrity. Collaborate across teams to translate needs into actions...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead complex operational solutions in enterprise automation, guiding pre-sales technical processes. Collaborate closely with customers and Account Executives to design pilots and ensure seamless trans...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K *

Grow your career with a collaborative sales team focused on empowering small businesses in the restaurant industry. Engage with clients to drive value and exceed quotas while cultivating lasting relat...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $180K *

Drive the technical strategy for AI across the organization, ensuring clarity and accountability in AI investments. Collaborate with cross-functional leaders to scale impactful AI initiatives, optimiz...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join our People team to drive impactful People programs and systems. Oversee strategic initiatives that enhance engagement and compliance while leading HR system improvements in a dynamic, high-growth...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $300K *

Join a team that's driving revenue growth by cultivating strategic accounts and client relationships. Leverage your sales expertise in solution selling and account management to maximize profitability...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive data excellence by designing, developing, and maintaining ETL/ELT pipelines across various platforms, ensuring quality and reliability to support analytics and AI workflows in a collaborative, d...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $195K *

Unlock your potential by building advanced entity matching solutions. Collaborate with a dedicated team to transform complex data into actionable insights, ensuring transparency and accuracy in every...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that drives strategic operations within the dynamic B2B software sector. Lead key initiatives, manage industry events, and shape performance metrics to scale output and enhance operational...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $125K *

Unlock potential by enhancing training, messaging, and sales tools to empower teams in a high-impact role that aligns product with sales strategies, driving performance and competitive advantage in th...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Transform enterprise relationships by driving strategic sales and fostering long-term partnerships in a dynamic AI infrastructure environment, engaging with C-level executives and guiding them through...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

The Startup Account Executive at OpenRouter will be responsible for driving new customer acquisition and building partnerships within the startup ecosystem. This role involves connecting with founders...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $136K *

Optimize financial operations by executing planning, reporting, and analysis for Core Services. Collaborate with cross-functional teams to enhance accuracy and efficiency in budgeting and forecasting...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Join a team that drives growth and profitability by managing relationships with mid-tier brand partners, balancing multiple priorities, and helping brands seize opportunities in resale for maximum GMV...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Lead the design and implementation of robust security measures to protect sensitive health information, ensuring compliance with HIPAA and other regulations while collaborating with cross-functional t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$216K - $240K *

Shape the future of grocery technology by leading the modernization of an on-demand ordering platform. Collaborate with cross-functional teams to create scalable, maintainable solutions, enhancing sys...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$70K - $100K *

Grow your career by managing the full sales cycle, providing exceptional customer service, and building relationships with clients in a dynamic team environment. Embrace opportunities for personal and...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $225K *

Lead the charge in transforming public safety operations with innovative sUAS solutions. Collaborate with agencies to deliver tailored drone technology, ensuring seamless integration and impactful dep...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.