Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Equipment Finance Capital Markets Syndication Manager
$136K - $245K *
Unlock potential by leading capital markets transactions, driving revenue growth, and managing client relationships. This role involves deal sourcing, structuring, and execution, with significant oppo...
2 weeks ago
Cross-Centers Service Delivery Operations Lead
$120K - $145K *
Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...
2 weeks ago
Clinical Sales Account Manager - Sioux Falls, SD
$80K - $85K *
Drive revenue growth by developing and implementing sales strategies for healthcare solutions. Build strong relationships with medical professionals, ensuring customer satisfaction and collaboration w...
2 weeks ago
Staff Forward Deployed Engineer
$254K - $297K *
Elevate customer experiences by diagnosing and resolving complex technical challenges. Contribute directly to product engineering initiatives while collaborating with strategic customers and internal...
Reposted 2 weeks ago
$139K - $220K *
Empower revenue teams by developing impactful sales enablement programs, tailored for Public Sector customers, enhancing their skills and tools to effectively deliver GitLab solutions across various g...
Reposted 2 weeks ago
Director, Strategic Partnerships
$168K - $285K *
Drive strategic partnerships by shaping and executing initiatives that align with AI and business priorities. Collaborate across teams to develop relationships and deliver measurable outcomes that enh...
Reposted 2 weeks ago
Senior Cost Manager / Quantity Surveyor - Construction
$130K - $150K *
Lead the charge in delivering exceptional cost management services, ensuring client objectives are met through effective communication, strategic planning, and proactive problem-solving in a dynamic c...
2 weeks ago
$105K - $135K *
Join a team that's transforming healthcare marketing by crafting compelling narratives and executing integrated campaigns that drive engagement and awareness for innovative cardiac solutions, while co...
2 weeks ago
Data Center COE Senior PLC Technician
$83K - $135K *
Unlock potential by leading complex field assignments in mission-critical power applications. Drive technical excellence in startup, commissioning, and troubleshooting of advanced switchgear and contr...
2 weeks ago
Account Manager (AgriBusiness/AgTech) - Pacific Northwest, Remote
$80K - $95K *
Engage with mid-market and enterprise accounts in row crops, driving renewals and new business growth. Collaborate with stakeholders to enhance customer success and leverage insights for operational e...
2 weeks ago
Engineering Manager, Proactive Security - Pods
$193K - $285K *
Redefine the future of security at scale by leading innovative product engineering efforts. Drive collaboration, technical vision, and proactive controls to ensure a secure and resilient delivery ecos...
Reposted 2 weeks ago
Associate Legal Counsel, Product & Privacy, Ads
$129K - $190K *
Empower cross-functional teams by providing expert legal counsel on product development, privacy, and compliance in the ad-tech space. Collaborate closely with engineering, marketing, and product team...
2 weeks ago
$49K - $117K *
Champion customer success by onboarding and supporting professional soccer accounts, enhancing performance through data integration and strategic insights, while driving client retention and expansion...
2 weeks ago
$175K - $400K *
Elevate your career by managing the lifecycle of vendor agreements and contracts. Collaborate across departments to ensure compliance and streamline workflows, safeguarding business interests while mi...
2 weeks ago
$100K - $130K *
Join a team that's dedicated to driving legal excellence and risk management. As a Senior Commercial Paralegal, you'll draft and negotiate agreements, coordinate legal responses, and support cross-dep...
2 weeks ago
Product Marketing Manager - Card Not Present (eCommerce) Processing & Value Added Solutions
$100K - $125K *
Join a dynamic team to shape the go-to-market strategy for innovative payment solutions. This role bridges technical capacities with merchant needs, driving adoption and enhancing experiences for onli...
Reposted 2 weeks ago
$110K - $130K *
Unlock potential by owning the end-to-end product surface, driving discovery, design, and migration while collaborating closely with users to solve real market problems in a dynamic healthcare environ...
2 weeks ago
$160K - $180K *
Unlock the potential of brand innovation by leading strategy and consumer insights for new product launches. Collaborate across teams to shape compelling narratives and ensure market readiness, drivin...
2 weeks ago
Senior Manager, Contracts Lifecycle Management
$120K - $145K *
Transform legal operations by leading technology assessments and implementations. Collaborate with clients to enhance contracting processes, leveraging expertise in CLM and AI solutions while mentorin...
Reposted 2 weeks ago
Senior Associate Sourcing Consultant
$80K - $95K *
Drive procurement excellence by supporting cross-functional teams in vendor governance and sourcing. Leverage analytical skills to improve processes and mitigate risks while crafting strategic solutio...
Reposted 2 weeks ago
Sr. Supervisor, Commercial Casualty Claims - Remote
$99K - $133K *
Lead the charge in supervising complex commercial casualty claims, ensuring effective management of 1st and 3rd party claims across multiple states. Drive operational excellence and foster team develo...
2 weeks ago
$231K - $244K *
Support business growth by drafting and negotiating partner agreements, providing strategic legal advice, and leading cross-functional projects. Collaborate with internal teams to ensure compliance an...
2 weeks ago
Manager, Policy and Compliance, Certification
$95K - $115K *
Lead the charge in overseeing compliance frameworks and regulatory trends, ensuring the certification team adapts to changes. Collaborate cross-functionally to integrate policy expertise and support c...
2 weeks ago
Project Manager - Medical Communications
$80K - $95K *
Advance your career by managing diverse medical communications projects, ensuring timely delivery and client satisfaction while leading multidisciplinary teams and maintaining strong relationships wit...
2 weeks ago
Solutions & Sales Enablement Specialist
$85K - $100K *
Join a team that's driving sales growth by delivering innovative workflow and content management solutions. Leverage your technical expertise and sales enablement skills to empower channel partners an...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.