Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$136K - $245K *

Unlock potential by leading capital markets transactions, driving revenue growth, and managing client relationships. This role involves deal sourcing, structuring, and execution, with significant oppo...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $85K *

Drive revenue growth by developing and implementing sales strategies for healthcare solutions. Build strong relationships with medical professionals, ensuring customer satisfaction and collaboration w...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$254K - $297K *

Elevate customer experiences by diagnosing and resolving complex technical challenges. Contribute directly to product engineering initiatives while collaborating with strategic customers and internal...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$139K - $220K *

Empower revenue teams by developing impactful sales enablement programs, tailored for Public Sector customers, enhancing their skills and tools to effectively deliver GitLab solutions across various g...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $285K *

Drive strategic partnerships by shaping and executing initiatives that align with AI and business priorities. Collaborate across teams to develop relationships and deliver measurable outcomes that enh...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $150K *

Lead the charge in delivering exceptional cost management services, ensuring client objectives are met through effective communication, strategic planning, and proactive problem-solving in a dynamic c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$105K - $135K *

Join a team that's transforming healthcare marketing by crafting compelling narratives and executing integrated campaigns that drive engagement and awareness for innovative cardiac solutions, while co...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $135K *

Unlock potential by leading complex field assignments in mission-critical power applications. Drive technical excellence in startup, commissioning, and troubleshooting of advanced switchgear and contr...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Engage with mid-market and enterprise accounts in row crops, driving renewals and new business growth. Collaborate with stakeholders to enhance customer success and leverage insights for operational e...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$193K - $285K *

Redefine the future of security at scale by leading innovative product engineering efforts. Drive collaboration, technical vision, and proactive controls to ensure a secure and resilient delivery ecos...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$129K - $190K *

Empower cross-functional teams by providing expert legal counsel on product development, privacy, and compliance in the ad-tech space. Collaborate closely with engineering, marketing, and product team...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$49K - $117K *

Champion customer success by onboarding and supporting professional soccer accounts, enhancing performance through data integration and strategic insights, while driving client retention and expansion...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$175K - $400K *

Elevate your career by managing the lifecycle of vendor agreements and contracts. Collaborate across departments to ensure compliance and streamline workflows, safeguarding business interests while mi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $130K *

Join a team that's dedicated to driving legal excellence and risk management. As a Senior Commercial Paralegal, you'll draft and negotiate agreements, coordinate legal responses, and support cross-dep...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$100K - $125K *

Join a dynamic team to shape the go-to-market strategy for innovative payment solutions. This role bridges technical capacities with merchant needs, driving adoption and enhancing experiences for onli...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by owning the end-to-end product surface, driving discovery, design, and migration while collaborating closely with users to solve real market problems in a dynamic healthcare environ...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Unlock the potential of brand innovation by leading strategy and consumer insights for new product launches. Collaborate across teams to shape compelling narratives and ensure market readiness, drivin...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Transform legal operations by leading technology assessments and implementations. Collaborate with clients to enhance contracting processes, leveraging expertise in CLM and AI solutions while mentorin...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Drive procurement excellence by supporting cross-functional teams in vendor governance and sourcing. Leverage analytical skills to improve processes and mitigate risks while crafting strategic solutio...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$99K - $133K *

Lead the charge in supervising complex commercial casualty claims, ensuring effective management of 1st and 3rd party claims across multiple states. Drive operational excellence and foster team develo...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$231K - $244K *

Support business growth by drafting and negotiating partner agreements, providing strategic legal advice, and leading cross-functional projects. Collaborate with internal teams to ensure compliance an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Lead the charge in overseeing compliance frameworks and regulatory trends, ensuring the certification team adapts to changes. Collaborate cross-functionally to integrate policy expertise and support c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Advance your career by managing diverse medical communications projects, ensuring timely delivery and client satisfaction while leading multidisciplinary teams and maintaining strong relationships wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$85K - $100K *

Join a team that's driving sales growth by delivering innovative workflow and content management solutions. Leverage your technical expertise and sales enablement skills to empower channel partners an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.