Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$177K - $243K *
Advance your career by leading a global compensation function, shaping strategies, and building a high-performing team. Collaborate with key stakeholders to drive compensation programs that align with...
2 weeks ago
$89K - $111K *
Accelerate growth by sourcing and closing new partnerships with accounting firms and service providers. Drive revenue through strategic relationship building and compelling agreements, ensuring seamle...
2 weeks ago
Staff Software Engineer, Program Structure & Trust
$150K - $180K *
Innovate by owning the architectural foundation for enterprise compliance. Lead complex initiatives, design scalable solutions, and drive alignment across teams to enhance security programs for divers...
2 weeks ago
Senior Account Executive, Business Outfitters
$100K - $120K *
Lead the charge in managing multi-million-dollar Key Accounts, driving revenue growth through strategic relationships and collaboration with internal teams. Own account strategies, exceed sales target...
2 weeks ago
Senior Developer, Business Systems
$102K - $142K *
Transform Salesforce systems by enhancing integrations and configurations. Collaborate with a dynamic team to support professional services and streamline project management, ensuring seamless operati...
2 weeks ago
$110K - $130K *
Drive client success by managing and expanding a portfolio of accounts, leveraging data insights to create tailored strategies that enhance business performance and foster strong relationships with st...
2 weeks ago
$80K - $110K *
Analyze diverse research projects to provide actionable insights for leadership. Collaborate with a dynamic team, utilizing AI tools and your curiosity to tackle complex questions and deliver clear, c...
2 weeks ago
$80K - $95K *
Transform automation processes by leading projects and collaborating with teams to develop innovative software solutions, applying engineering principles to enhance operational efficiency in the pork...
2 weeks ago
Senior Infrastructure Test Engineer, DevOps
$120K - $140K *
Unlock your potential as you innovate automated testing solutions for AWS infrastructures and CI/CD pipelines. Collaborate with cross-functional teams to enhance deployment confidence and streamline v...
Reposted 2 weeks ago
Director Product Management - AI / ML Platform
$100K - $231K *
Drive innovation in clinical decision support by leading the development of an AI-powered insights platform. Collaborate with cross-functional teams to transform complex data into actionable solutions...
2 weeks ago
$140K - $200K *
Lead the charge in expanding rail engineering practices across regions, providing technical expertise, managing client relationships, and ensuring successful project delivery while mentoring teams and...
2 weeks ago
BIM VDC Engineer IV - Critical Infrastructure
$99K - $120K *
Drive BIM and VDC initiatives for critical infrastructure projects, leading model management and coordination efforts. Collaborate with teams to ensure accurate, constructible models throughout the co...
2 weeks ago
Software Configuration Manager
$110K - $130K *
Lead the charge in optimizing IT configuration management practices to enhance service lifecycle support, ensuring accuracy of configuration items and improving operational efficiency across enterpris...
Reposted 2 weeks ago
$225K - $275K *
Lead the charge in redefining Total Rewards strategy, enhancing compensation, equity, and benefits to attract and retain top talent while anticipating workforce shifts driven by AI and market trends...
Reposted 2 weeks ago
Deputy Chief of Party II, Technical, Continuity of Integrated Health Services
$95K - $117K *
Champion integrated health initiatives across multiple countries, providing strategic oversight and leadership for malaria, maternal health, and infectious disease programs. Ensure quality interventio...
2 weeks ago
Senior Product Manager, 1: Many Merchant Growth
$173K - $255K *
Transform the partner integration landscape by leading a team focused on optimizing partnerships, enhancing onboarding ease, and driving accelerated growth through innovative product strategies and cr...
Reposted 2 weeks ago
Principal AI Platform Engineer
$139K - $232K *
Elevate enterprise AI capabilities by designing and implementing Generative AI solutions. Lead technical discussions, mentor talent, and drive best practices to ensure scalable, responsible AI adoptio...
2 weeks ago
Associate Director, Manufacturing Business Operations & Strategy
$203K - $228K *
Join a dynamic team to lead strategic manufacturing operations, integrating technical and business insights to drive successful commercialization and lifecycle management of biologics and cell therapi...
2 weeks ago
Relationship Manager, Equipment Finance, Environmental Waste
$107K - $179K *
Drive success by managing key business relationships in the Environmental Waste Space, leveraging industry knowledge to identify financing solutions and expand opportunities while ensuring compliance...
2 weeks ago
$135K - $160K *
Champion the development of an autonomous AI platform through full-stack engineering, enhancing multi-agent systems and ensuring robust quality and safety standards across production deployments...
Reposted 2 weeks ago
$140K - $170K *
Join a team that's shaping the future of cybersecurity by designing and maintaining robust Splunk data pipelines. Collaborate with cross-functional teams to enhance operational processes and ensure da...
2 weeks ago
Senior Datadog Security & Observability Engineer
$125K - $150K *
Elevate security observability by enhancing Datadog's capabilities across cloud and corporate environments, ensuring actionable detection aligned with real-world threats while collaborating with cross...
Reposted 2 weeks ago
$110K - $130K *
Accelerate growth at a leading cyber security provider by driving enterprise sales. Utilize your strategic selling skills and build key relationships with C-level execs to implement innovative solutio...
Reposted 2 weeks ago
Senior Product Manager, Consumer (B2C)
$120K - $145K *
Inspire innovation and drive growth as you lead the consumer product line across web, mobile, and desktop platforms, crafting a unified user experience and championing customer-centric strategies for...
Reposted 2 weeks ago
$110K - $130K *
Lead the charge in shaping product marketing strategies that elevate brand visibility, drive customer engagement, and support sales growth through innovative messaging and cross-functional collaborati...
Reposted 2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.