Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$183K - $203K *

Lead mission-critical RF and SATCOM systems, ensuring reliable operations through hands-on troubleshooting, maintenance, and collaboration with technical teams to support seamless mission execution ac...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$108K - $135K *

Help us navigate legal complexities by drafting documents, conducting research, and providing counsel. Collaborate with our legal team to ensure compliance and support business objectives in a dynamic...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to delivering high-quality ServiceNow projects. As a Project Manager, you'll oversee project performance, manage client relationships, and ensure adherence to best practic...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Join a team that's driving project excellence by leading a diverse group of Project Managers. You'll optimize resources, enhance delivery outcomes, and foster high performance across critical VA initi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$146K - $234K *

Elevate AI solutions by architecting integration frameworks for third-party tools within secure environments, ensuring compliance and security while driving innovation in fraud detection and preventio...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$112K - $179K *

Reimagine the future of ServiceNow development by designing and supporting custom applications. Leverage your expertise to solve complex problems, mentor junior developers, and drive innovative soluti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Lead the charge in conducting medical record reviews and applying clinical judgment to ensure accurate claim payment decisions while supporting fraud investigations and compliance efforts...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$86K - $138K *

Join us to support the onboarding and configuration of Google Cloud Platform for our Federal Government client, ensuring seamless infrastructure operations and automation while providing expert cloud...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$128K - $252K *

Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$88K - $105K *

Lead the charge in complex financial reporting and reinsurance accounting, ensuring accuracy and compliance while driving process improvements and providing exceptional service to internal and externa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $153K *

Elevate your career by leading the Inside Sales strategy to drive growth, enhance customer engagement, and develop a high-performing team. Collaborate across functions to optimize processes and delive...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$79K - $116K *

Partner with us to drive sales growth through strategic account management, leveraging relationships with retailers and suppliers. You'll design and execute impactful marketing programs, ensuring alig...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Lead FedRAMP compliance initiatives, coordinating cross-functional teams to ensure project success. Manage execution of strategies, schedules, budgets, and stakeholder engagements while driving accoun...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$86K - $112K *

Deliver innovative Salesforce solutions by leading design, development, and integration efforts. Collaborate with cross-functional teams to enhance operational efficiency and drive business value thro...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $125K *

Discover a role where you translate engineering designs into precise piping drawings, coordinating with various teams to ensure project excellence in industrial contexts like water/wastewater and manu...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$115K - $120K *

Champion quality assurance by developing and maintaining automated test solutions. Collaborate with cross-functional teams to integrate testing into CI/CD pipelines, ensuring comprehensive coverage an...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Lead the development of high-value proposals, coordinating cross-functional teams to ensure compliance and produce compelling content. Oversee the full proposal lifecycle, enhancing competitiveness th...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $135K *

Lead the charge in delivering complex projects from initiation to close, ensuring alignment among stakeholders, effective risk management, and adherence to timelines while utilizing AI tools to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion healthcare project delivery by managing design and construction lifecycles, ensuring compliance with quality, safety, and budget standards while fostering collaboration among stakeholders to...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$87K - $120K *

Transform the nonprofit sector by managing agency relationships, driving growth, and ensuring compliance. Leverage your underwriting expertise to enhance portfolio performance and develop new business...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's shaping the future of claims management for Non-Profits. Lead and mentor a skilled team, providing strategic direction on complex claims while ensuring exceptional service and compl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock your potential as a Commercial Property General Adjuster, where you'll investigate and resolve complex claims, negotiate settlements, and mentor junior staff in a dynamic environment. Embrace t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $155K *

Analyze complex commercial claims, ensuring thorough investigations and effective resolutions. Collaborate with internal and external parties to manage litigated and non-litigated claims, leveraging s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $200K *

Champion large-scale enterprise application initiatives, leading Agile teams to drive digital transformation, manage program execution, and ensure alignment with strategic objectives while fostering c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Contribute to the development of a robust Kubernetes control plane, enhancing multi-cloud infrastructure and driving scalable architecture for enterprise-grade cloud services...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.