Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Senior E-Commerce & Small Account Growth Manager
$105K - $140K *
Join us to optimize the commercial operating plan for small accounts, enhancing customer experiences and driving measurable growth through hands-on strategies and collaboration across teams...
2 days ago
Field Service Supervisor (LCMS) - MD/DC
$83K - $115K *
Transform service delivery by leading a skilled team of engineers, ensuring operational excellence and customer satisfaction through effective coordination and relationship management. Drive continuou...
2 days ago
$88K - $112K *
Drive the development and execution of a comprehensive enterprise risk management program, collaborating across global functions to enhance risk governance, reporting, and education while maintaining...
2 days ago
$240K - $285K *
Help us shape a transformative People Operations strategy that drives organizational effectiveness and talent development. Lead initiatives from concept to execution, fostering a culture of accountabi...
2 days ago
$132K - $272K *
Elevate retail partnerships by developing integrated strategies that drive growth and innovation. Collaborate across teams to transform complex opportunities into actionable plans, enhancing commerce...
2 days ago
Enterprise Architect - Consumer Banking & Marketing
$139K - $232K *
Unlock potential by providing enterprise architecture leadership for Retail and Consumer Banking. Shape technology strategies and roadmaps across various banking capabilities, ensuring alignment with...
2 days ago
Customer Success Manager (West Region)
$80K - $95K *
Champion customer success by owning relationships, driving adoption, and ensuring renewals. Leverage deep trust to generate qualified leads while proactively engaging law firm accounts to enhance thei...
Reposted 2 days ago
$88K - $105K *
Drive the execution of influencer marketing strategies, managing relationships with creators and overseeing performance metrics to maximize ROI. Lead a team while collaborating with cross-functional p...
2 days ago
Group Director, Consumer Services
$150K - $180K *
Join a dynamic team as a senior leader, driving client relationships and revenue growth in lead-generation sectors. You'll manage a diverse portfolio, ensuring lead quality and speed while leveraging...
2 days ago
Vice President Growth Marketing
$200K *
Lead the charge in driving enterprise growth marketing strategies, optimizing pipeline performance, and orchestrating cross-functional initiatives to scale demand generation and revenue outcomes acros...
2 days ago
Commercial & Industrial Account Manager
$80K - $95K *
Join a team that's focused on driving growth and customer satisfaction in the commercial and industrial sector. Leverage your sales expertise to manage accounts, resolve customer issues, and identify...
2 days ago
$80K - $95K *
Help us manage diverse projects that drive strategic growth and collaboration across teams. As a key member of the EPMO, you'll ensure project success through effective stakeholder management and cont...
2 days ago
$116K - $171K *
Lead the charge in optimizing partner experiences and driving program modernization. This role requires strategic project management and a focus on automation to enhance the lifecycle of partnerships...
2 days ago
Director of Marketplace Channel Management (Amazon & TikTok Shop)
$145K - $175K *
Strategize and execute marketplace growth initiatives on Amazon and TikTok Shop, driving sales and profitability while managing P&L and aligning with omnichannel objectives. Lead operations, performan...
2 days ago
Forward Deployed Engineer, Ecosystem
$179K - $224K *
Engage with partner engineering teams to design and prototype integrations that enhance our AI platform. This role demands hands-on engineering, scalable architecture, and translating findings into im...
Reposted 2 days ago
Senior Claims Specialist/Claims Technical Director - Great American Risk Solutions
$90K - $125K *
Transform complex commercial casualty claims management by leveraging your expertise in construction-related exposures and litigation. Collaborate with a dedicated team to deliver exceptional outcomes...
2 days ago
Associate Vice President - Strategic Accounts & Client Success - Remote
$144K - $240K *
Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...
2 days ago
Category Growth Manager, Women's Hormones
$130K - $150K *
Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...
2 days ago
Access Manager - Healthcare Claims, PAs, Reimbursement & Appeals
$74K - $87K *
Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...
2 days ago
Senior Marketing Operations Specialist
$72K - $99K *
Unlock the potential of marketing operations by managing our MarTech stack, optimizing processes, and collaborating across teams to drive growth and efficiency in marketing initiatives...
2 days ago
Sr. Manager, Marketing Compliance
$110K - $130K *
Lead compliance efforts in marketing by ensuring all materials meet legal standards. Collaborate with cross-functional teams to apply guidelines effectively while maintaining a keen attention to detai...
2 days ago
Principal Scientist/Associate Director, Translational Medicine
$190K - $210K *
Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...
2 days ago
$80K - $95K *
Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...
2 days ago
$200K - $250K *
Partner with us to drive growth as our Chief Marketing Officer, leading innovative strategies and systems to generate member acquisition across multiple markets, ensuring sustainable success and perfo...
2 days ago
Principal SAP Retail POS Consultant
$145K - $180K *
Transform retail operations by serving as the primary SAP POS expert for DoD S/4HANA implementations, ensuring alignment with operational goals and financial reporting while bridging technical teams a...
2 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.