Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$110K - $130K *

Transform the mobile product experience by leading design initiatives that empower creators and engage fans. Drive product quality and innovation through hands-on design, collaboration, and strategic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$165K *

Join us to lead a dynamic Sales Development team, driving pipeline growth through strategic outbound and inbound initiatives. Collaborate with cross-functional teams to enhance performance and leverag...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$177K - $212K *

Develop and deploy advanced ML models for multi-object tracking, ensuring robust performance in autonomous vehicles. Collaborate with cross-functional teams to enhance tracking algorithms and improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$172K - $215K *

Join a team that's transforming public safety through innovative drone solutions. Lead complex deployments, drive technical wins, and shape the future of sUAS operations while mentoring a talented eng...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$94K - $169K *

Transform AI product strategies by leading cross-functional teams to identify, evaluate, and implement solutions that enhance clinical and operational workflows, ensuring alignment with institutional...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead a dynamic team in managing customer orders, ensuring accuracy and timely delivery while enhancing interdepartmental collaboration and customer satisfaction across Sales and Service Delivery opera...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Unlock technical excellence by providing critical support for product implementations, ensuring seamless installations and troubleshooting for diverse technologies. Collaborate with teams to enhance c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$125K - $150K *

Shape compliance excellence by overseeing post-closing functions, managing risks, and driving continuous improvement. Collaborate with stakeholders to ensure adherence to regulations and enhance the C...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Shape the future of K-12 literacy by leading a dynamic sales team, driving growth, and building lasting partnerships with educators. Leverage your expertise to develop strategies that enhance educatio...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead and inspire a blended team of developers to enhance AI-driven legal automation platforms, ensuring technical excellence, delivery, and collaboration across functions while managing architecture...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$109K - $260K *

Lead the charge in transforming enterprise technology through innovative AI platforms and process automation. Oversee architecture, engineering, and vendor management to ensure operational excellence...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$170K - $190K *

Oversee the technical planning and implementation of control systems, ensuring effective deployment and support for FRCS Petaluma. Lead project management efforts, maintain documentation, and provide...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$115K - $130K *

Elevate operational efficiency by providing high-level administrative support to senior leadership, coordinating meetings, managing correspondence, and ensuring compliance with Navy directives while f...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$96K - $118K *

Join a dynamic team to lead pricing and underwriting functions, driving financial analysis and risk evaluation. Collaborate with supervisors and analysts to enhance pricing strategies and support clie...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $166K *

Manage and lead projects focused on surveillance and radar systems, ensuring effective collaboration across teams. Drive modernization and integration efforts while meeting FAA standards and deliverin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $216K *

Lead the charge in managing a software engineering team, driving the design and delivery of secure satellite ground communication services while fostering best practices and ensuring alignment with mi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$66K - $106K *

Lead the charge in producing federal species range maps, ensuring compliance with FWS standards. Collaborate with government SMEs to integrate marine and anadromous species data, enhancing ESA researc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $216K *

Elevate data integration and engineering efforts to enhance the CMS Fraud Prevention System. Collaborate with teams to design and operate data pipelines, ensuring compliance and security while optimiz...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$110K - $175K *

Champion client relationships by managing a portfolio of Corporate Banking clients, focusing on deposit growth and new business development. Drive solutions that meet client needs while contributing t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by providing strategic leadership for a national remote case management team, ensuring service excellence, operational consistency, and client satisfaction while collaborating with...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Drive the Arbitration Team's success by leading initiatives that enhance performance, streamline processes, and foster client relationships. Oversee daily operations and ensure exceptional service del...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$83K - $129K *

Lead the charge in advanced compliance activities, ensuring administrative solutions align with laws and regulations. Utilize AI tools to enhance efficiency, guide teams, and deliver scalable complian...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $125K *

Empower your career by driving the integration and migration of data for a vital financial management system. Collaborate with experts to enhance system reliability and operational efficiency in a ful...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.