Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$120K - $160K *
Transform communications strategy and execution for a growing organization. Lead branding, messaging, and digital presence to enhance visibility and engagement across diverse audiences, while collabor...
2 weeks ago
Regional Sales Director - Great Lakes / Ohio Valley ONLY
$140K *
Shape the future of public safety SaaS by leading a high-performing sales team, driving growth, and executing strategic initiatives in a rapidly evolving market. Collaborate cross-functionally to enha...
2 weeks ago
$100K - $120K *
Partner with us to drive revenue growth and strategic account management across a diverse portfolio. You'll own the full sales cycle, collaborate with cross-functional teams, and build lasting relatio...
2 weeks ago
$90K - $120K *
Empower our brand by driving in-store execution, building relationships, and enhancing customer experiences across key accounts. Collaborate with teams to optimize sales and training while ensuring br...
2 weeks ago
$170K - $230K *
Pioneer a high-performing sales team, driving revenue growth through strategic leadership and client engagement. Shape the future of our corporate sales efforts by optimizing processes and fostering c...
2 weeks ago
$160K - $193K *
Shape the future of autonomous vehicle testing by leading a team to develop and implement innovative test strategies, ensuring safety and performance standards are met across multiple vehicle programs...
2 weeks ago
Founding Revenue Marketing Lead
$120K - $150K *
Empower our growth by leading revenue marketing initiatives that drive predictable pipeline for sales. You'll strategize and execute impactful programs across events, campaigns, and account-based mark...
2 weeks ago
$110K - $130K *
Reimagine medical communication by leading a team of writers to craft regulatory and scientific documents. Oversee projects, ensuring clarity and quality for diverse audiences while adhering to timeli...
Reposted 2 weeks ago
$110K - $130K *
Elevate product design by leading innovative initiatives, guiding cross-functional teams, and shaping user experiences from concept to delivery. Drive design excellence and foster a culture of feedbac...
2 weeks ago
Senior Implementation Consultant (Intacct)
$100K - $115K *
Partner with us to lead complex Sage Intacct implementations, guiding clients through analysis, design, and optimization. Leverage your expertise to enhance client relationships and drive successful p...
2 weeks ago
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
Reposted 2 weeks ago
Broadcast Engineer, Live Sports Production, Prime Video Live Sports
$127K - $222K *
Champion the technical backbone of live sports broadcasts, ensuring seamless signal flow and infrastructure management. Collaborate across teams to deliver high-quality productions while thriving in d...
2 weeks ago
Senior Quality Operations Specialist, Audit
$74K - $98K *
Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...
2 weeks ago
$173K - $288K *
Empower your career by owning global tax provisions and compliance. Lead audits, drive process improvements, and support M&A initiatives while collaborating across teams to enhance tax strategies and...
2 weeks ago
Appian Forward Deployed Product Owner
$148K - $247K *
Join a team that's driving digital transformation in financial services. Leverage your expertise in Appian to design and optimize workflows, collaborate with stakeholders, and enhance client-centric s...
2 weeks ago
Lead Pricing and Costing Analyst - Remote
$108K - $145K *
Drive impactful pricing strategies and cost analysis for complex proposals, ensuring compliance and competitiveness. Collaborate with cross-functional teams to deliver actionable insights and recommen...
2 weeks ago
Engineering Manager - Member Experience
$179K - $224K *
Join a team that's dedicated to delivering high-quality member-facing systems. As an Engineering Manager, you'll lead a squad through the entire development lifecycle, ensuring accountability, quality...
2 weeks ago
Director, Pricing and Profitability
$124K - $223K *
Shape the future of pricing strategy by leading a dynamic team to optimize profitability and drive strategic decisions across SaaS and services. Collaborate with executives to enhance customer value a...
2 weeks ago
$160K - $193K *
Lead the charge in HiL testing for autonomous trucks, guiding a team to ensure robust verification and validation. Shape the test strategy, align with safety standards, and collaborate across teams to...
2 weeks ago
Senior Revenue Operations & Analytics Director
$150K - $198K *
Drive revenue growth by optimizing data systems and processes. Collaborate with cross-functional teams to enhance forecasting, analytics, and AI solutions, ensuring informed business decisions and str...
2 weeks ago
$160K - $179K *
Shape the future of gameplay animation by creating high-quality character animations, collaborating with cross-functional teams, and driving the artistic vision while working independently to resolve...
2 weeks ago
$135K - $160K *
Champion modernization initiatives by designing and overseeing transformation solutions, integrating cutting-edge GenAI technology, and ensuring alignment with business objectives to drive impactful m...
Reposted 2 weeks ago
Enterprise Account Executive - FSI
$109K - $207K *
Drive strategic enterprise sales to Fortune 100/500 companies, leveraging strong negotiation skills and a proven track record to exceed quotas in a dynamic and collaborative environment...
Reposted 2 weeks ago
Lead Clinical Pharmacist, Oncology Programs
$120K - $145K *
Join a team that's redefining oncology care by overseeing clinical standards, evaluating therapies, and engaging with providers. You'll play a key role in shaping patient eligibility and treatment pro...
2 weeks ago
$129K - $168K *
Manage and elevate accounts payable operations by leading teams, optimizing workflows, and ensuring compliance with best practices. Collaborate cross-functionally to drive operational excellence and e...
Reposted 2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.