Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Specialist, Technology Solutions
$90K - $100K *
Transform business needs into actionable requirements, driving system enhancements and operational improvements. Collaborate across teams to ensure clarity and alignment, leveraging data analysis and...
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$90K - $110K *
Empower payroll operations by leading the transition to in-house systems, managing multi-state US and Canadian payroll, and strategizing for India payroll compliance while ensuring accuracy and effici...
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Senior Integrated Campaign Manager
$110K - $130K *
Join a team that's driving integrated demand generation campaigns across multiple channels. You'll collaborate with cross-functional teams to launch products, optimize pipeline strategies, and enhance...
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$75K - $90K *
Accelerate your career as you manage inventory accounting and cash flows, ensuring accuracy across multiple business units. Collaborate with finance and supply chain teams to identify risks and opport...
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Engineering Product Manager - Mobility
$179K - $254K *
Join a team that's driving the future of mobility and IoT! Oversee product lifecycles, collaborate with executives, and navigate complex networks to align cutting-edge solutions with customer needs an...
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Senior Consultant - Clinical Operations
$89K - $148K *
Drive your career with impactful consulting in healthcare, enhancing operational efficiency and financial performance for provider organizations through data analysis and project management...
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$110K - $130K *
Join our dynamic team as you lead equity program operations, ensuring compliance and enhancing processes. You'll be the go-to expert for equity-related matters, driving initiatives that support our ra...
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$216K - $228K *
Transform the research landscape by defining and leading user research practices that connect customer insights to product design across multiple foundational areas, driving high-quality deliverables...
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$225K - $300K *
Shape the future of our global accounting function by leading the controllership organization, driving IPO readiness, and establishing robust financial controls to support a high-growth, multi-entity...
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Full Stack Engineer (Go and React)
$110K - $130K *
Engineer innovative cloud-native applications, developing scalable backend services and modern web solutions using Golang and React. Collaborate with cross-functional teams to solve complex challenges...
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Advanced Practice Provider - General & Bariatric Surgery
$90K - $110K *
Manage patient care under physician supervision, focusing on complex cases and collaborating with healthcare teams to ensure optimal outcomes and continuity of care...
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$170K - $210K *
Engage as the senior creative leader, ensuring top-tier quality and performance across all creative outputs. Drive a culture of testing and learning while fostering strong client relationships and lea...
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Associate Product Manager, Data Governance
$105K - $168K *
Empower data-driven decisions by contributing to our Enterprise Data Governance Program. Collaborate with cross-functional teams to enhance data trustworthiness and compliance, ensuring a scalable and...
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Engineering Manager, Data Streaming
$225K - $265K *
Accelerate progress at a mission-critical team, leading Data Streaming to enhance data ingestion pipelines. Build a skilled team, ensure pipeline reliability, and collaborate cross-functionally to sup...
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$225K - $265K *
Lead and mentor a diverse team of backend engineers in EDR remediation, transforming insights into actionable product capabilities while managing scope and fostering collaboration across engineering t...
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$95K - $115K *
Grow your career with a dynamic team focused on maximizing sales and building relationships in the specialty pharmaceutical sector. Drive strategic initiatives and collaborate across functions to achi...
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Senior Advisor, Staff Well-Being and Workforce Resilience
$95K - $115K *
Transform staff well-being by leading strategic initiatives that enhance resilience and psychosocial support across diverse, high-stress environments, ensuring alignment with organizational priorities...
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$100K - $120K *
Join a creative team leading innovative marketing strategies to enhance brand visibility, engage municipal clerks, and drive demand for our unique product suite. Collaborate closely and execute impact...
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$80K - $100K *
Lead strategic sales initiatives to enhance Wireless, EMC, and Product Safety revenue. Cultivate new and existing customer relationships while driving technical discussions and solutions across divers...
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CIAM Product Manager - Capabilities & Intelligence
$71K - $125K *
Lead the execution of CIAM strategy by optimizing authentication intelligence and fraud detection tools. Collaborate with cross-functional teams to enhance security, reduce friction, and drive data-in...
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Senior Servicing Officer (Institutional Capital Group)
$71K - $125K *
Transform complex loan servicing processes as a Senior Servicing Officer, managing a diverse portfolio in commercial real estate. Contribute to client partnerships and lead initiatives, while expandin...
Reposted today
$80K - $150K *
Unlock secure customer experiences by designing and implementing identity solutions. Collaborate with cross-functional teams to enhance authentication processes, ensuring seamless onboarding and login...
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Sr. Manager Regulatory Affairs, Advertising & Promotion (Remote)
$150K - $245K *
Empower your career by leading regulatory advertising initiatives, ensuring compliance while collaborating with cross-functional teams to develop impactful product messaging for marketed and pipeline...
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Manager Regulatory Affairs, Advertising & Promotion (Remote)
$128K - $210K *
Manage regulatory activities for advertising and promotion, ensuring compliance while collaborating with cross-functional teams to develop impactful product messaging and materials that align with com...
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$150K - $190K *
Unlock potential by designing scalable data models and ensuring data quality. Collaborate with cross-functional teams to translate business needs into technical solutions, driving analytics excellence...
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What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.