Explore senior data scientist opportunities with organizations seeking experienced professionals to turn complex data into meaningful business results. Ladders features vetted jobs paying $100,000 or more, helping you focus your search on roles that match your skills, leadership experience, and compensation goals.
Senior data scientists design analytical approaches, build and evaluate statistical and machine learning models, and translate findings into practical recommendations. They work with product, engineering, business, and executive teams to identify opportunities, guide decisions, and deliver data-driven solutions.
Employers often look for advanced experience in Python or R, SQL, statistical analysis, machine learning, experimentation, and data visualization. Senior candidates may also bring expertise in cloud platforms, large-scale data systems, model deployment, and responsible AI. Clear communication, sound judgment, and the ability to mentor teammates are also valuable.
Senior data scientists can find opportunities across technology, finance, healthcare, retail, consulting, and other data-intensive industries. Depending on the organization and role, experienced professionals may progress into staff or principal data scientist positions, analytics leadership, or specialized AI and machine learning roles. Browse Ladders for vetted openings paying $100,000 or more.
Use Ladders to explore opportunities aligned with your expertise and career ambitions. Review each listing for responsibilities, qualifications, location, and compensation details, then apply to roles that fit your goals.
Scientific Data Architect - Biologics Manufacturing & Quality Control
$140K - $240K *
Shape the future of biologics manufacturing by designing data models that integrate manufacturing processes, laboratory results, and product quality. Collaborate with cross-functional teams to enhance...
2 days ago
Principal Machine Learning Engineer, Recommendations
$150K - $180K *
Transform healthcare by leading the development of an AI-driven discovery platform. Collaborate with cross-functional teams to create intelligent systems that enhance physician knowledge retrieval and...
2 weeks ago
Senior Machine Learning Engineer, Simulation
$130K - $200K *
Elevate the future of autonomous driving by developing scalable vehicle simulation models. Collaborate with diverse teams to apply cutting-edge deep learning techniques, enhance model accuracy, and en...
Reposted 3 weeks ago
$135K - $160K *
Shape the future of machine learning by driving development cycles, enhancing iteration speed, and overcoming bottlenecks. Collaborate with a goal-oriented team to achieve impactful results in a dynam...
3 days ago
$109K - $148K *
Unlock potential by driving data-driven solutions for complex challenges. Collaborate with stakeholders to enhance operational efficiency and support national security initiatives through advanced dat...
1 week ago
$109K - $148K *
Optimize data-driven solutions to enhance mission-critical operations. Leverage advanced analytics and machine learning to support Defense & Intelligence Programs, driving impactful results for nation...
1 week ago
$96K - $136K *
Innovate AI adoption and process transformation by leading cross-functional initiatives, integrating analytics and automation to enhance business workflows and deliver measurable improvements for stak...
3 days ago
$96K - $136K *
Unlock potential by leveraging advanced analytics to drive product strategy and performance. Collaborate with cross-functional teams to deliver actionable insights and mentor junior data scientists, e...
3 days ago
Research Scientist in Biomedical Data Science
$88K - $105K *
Join a dynamic team to analyze genomic data, providing insights that drive research. Collaborate with diverse scientists, develop analysis pipelines, and contribute to innovative projects in a fast-pa...
Today
Senior Econometrician and Software Developer
$100K - $120K *
Lead the charge in advancing econometric software development by collaborating with a dynamic team to enhance statistical features, validate methods, and engage with users through various platforms, e...
1 week ago
Senior Architect, Model Performance and Post-Training
$224K - $431K *
Engineer cutting-edge performance models for coding tasks, enhancing large language models through empirical analysis and optimization. Collaborate with cross-functional teams to translate insights in...
2 weeks ago
Senior Architect, Model Performance and Post-Training
$224K - $431K *
Empower the future of coding by driving performance modeling and evaluation of advanced language models. Collaborate with cross-functional teams to enhance coding capabilities, optimize training, and...
2 weeks ago
Senior Machine Learning Engineer, SageMaker Inference
$168K - $227K *
Join a dynamic team to optimize ML inference systems for Generative AI, enhancing performance and scalability. Collaborate with experts to innovate solutions that empower AWS customers and shape the f...
2 days ago
$191K - $297K *
Lead and evolve a high-performing data science team to enhance customer product discovery through advanced analytics, experimentation, and AI-driven solutions, ensuring impactful decision-making and m...
1 week ago
$95K - $115K *
Elevate your career by leveraging advanced data analytics and machine learning to drive impactful insights and solutions. Collaborate on big data platforms, develop algorithms, and enhance data visual...
2 days ago
Staff Machine Learning Engineer, Ads ML Efficiency
$230K - $322K *
Optimize machine learning infrastructure and tooling to enhance efficiency, reduce costs, and improve performance. Collaborate with cross-functional teams to drive productivity and scalability in ML s...
4 weeks ago
$190K - $220K *
Partner with us to drive data-led investment strategies, leveraging your expertise in data science to enhance decision-making and value creation. Collaborate with teams to develop innovative tools and...
1 week ago
$206K - $216K *
Join a dynamic team to design and optimize machine learning pipelines for e-commerce, leveraging advanced models and data governance to enhance personalization across multiple brands and markets...
1 week ago
$130K - $155K *
Lead the charge in developing cutting-edge generative AI solutions that drive impactful business transformations. Collaborate with leaders across functions to enhance AI capabilities while ensuring sc...
Reposted 1 week ago
$120K - $250K *
Drive innovation in data science by leading a talented team to transform life sciences data into actionable insights. Collaborate with leadership to implement AI strategies and ensure the delivery of...
1 week ago
$120K - $250K *
Champion a team of data scientists and AI/ML engineers to drive innovative analytics solutions in life sciences. Collaborate with leadership to execute AI strategies, ensuring robust data infrastructu...
1 week ago
$120K - $250K *
Shape the future of data science in life sciences by leading a talented team to implement AI-driven solutions. Collaborate with global leaders to transform strategy into impactful analytics and foster...
1 week ago
Sr. Data Scientist (Remote Eligible)
$110K - $184K *
Empower data-driven decisions by designing advanced analytics engines and AI solutions. Collaborate with stakeholders to create effective models, optimize retrieval performance, and promote data liter...
Reposted 6 days ago
Staff Machine Learning Engineer, Data Curation & Dataset Strategy
$150K - $180K *
Take ownership of data strategy for AI-driven vehicle systems, guiding data ingestion, selection, and quality. Collaborate across teams to optimize storage and enhance model training, ensuring efficie...
1 week ago
Senior Principal Machine Learning Engineer (Hybrid)
$132K - $251K *
Innovate AI/ML solutions within engineering systems, leading end-to-end lifecycle management and integration. Collaborate across teams to enhance capabilities and standards, driving productivity and o...
Reposted 1 week ago
What does a Senior Data Scientist do?
A Senior Data Scientist uses statistics, programming, and machine learning to analyze data, develop models, and inform business or product decisions. The role often includes collaborating across teams and mentoring other data professionals.
What qualifications are common for Senior Data Scientist jobs?
Employers commonly seek substantial data science experience, proficiency in Python or R and SQL, knowledge of statistical methods and machine learning, and the ability to communicate insights. Requirements vary by company and industry.
What industries hire Senior Data Scientists?
Senior Data Scientists work in technology, financial services, healthcare, retail, consulting, and many other industries that use data to improve products, operations, or decision-making.
How can I find Senior Data Scientist jobs paying $100,000 or more?
Browse vetted Senior Data Scientist listings on Ladders and review compensation, qualifications, and responsibilities to find opportunities aligned with your experience and career goals.