Explore senior data scientist opportunities with organizations seeking experienced professionals to turn complex data into meaningful business results. Ladders features vetted jobs paying $100,000 or more, helping you focus your search on roles that match your skills, leadership experience, and compensation goals.
Senior data scientists design analytical approaches, build and evaluate statistical and machine learning models, and translate findings into practical recommendations. They work with product, engineering, business, and executive teams to identify opportunities, guide decisions, and deliver data-driven solutions.
Employers often look for advanced experience in Python or R, SQL, statistical analysis, machine learning, experimentation, and data visualization. Senior candidates may also bring expertise in cloud platforms, large-scale data systems, model deployment, and responsible AI. Clear communication, sound judgment, and the ability to mentor teammates are also valuable.
Senior data scientists can find opportunities across technology, finance, healthcare, retail, consulting, and other data-intensive industries. Depending on the organization and role, experienced professionals may progress into staff or principal data scientist positions, analytics leadership, or specialized AI and machine learning roles. Browse Ladders for vetted openings paying $100,000 or more.
Use Ladders to explore opportunities aligned with your expertise and career ambitions. Review each listing for responsibilities, qualifications, location, and compensation details, then apply to roles that fit your goals.
$170K - $215K *
Lead a dynamic team of data scientists to innovate and implement machine learning solutions that drive business impact. Shape the future of data science by mentoring talent, collaborating with stakeho...
2 weeks ago
Senior Privacy Biostatistician - Risk Analytics
$145K - $150K *
Elevate your career by leading statistical disclosure control strategies for complex health datasets. Mentor junior staff and ensure compliance with HIPAA while driving improvements in data utility an...
Today
Lead Applied Scientist, NBA – Reinforcement Learning
$129K - $177K *
Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...
4 days ago
$120K - $145K *
Unlock potential by driving the development of cutting-edge AI and data platforms. Collaborate with cross-functional teams to design, deploy, and scale intelligent applications, ensuring robust integr...
2 weeks ago
$132K - $157K *
Join a team that's dedicated to ensuring compliance and transparency in financial reporting. As a Senior Data Analyst, you'll collaborate across departments to organize data, draw insights, and suppor...
2 weeks ago
Senior Data Science Manager, Predictive Analytics & AI – US?Commercial
$150K - $180K *
Unlock innovative AI and machine learning solutions to drive data-driven decisions across U.S. Commercial operations, enhancing insights into patient populations and healthcare provider behavior for s...
4 weeks ago
Senior Forward Deployed AI Architect (GenAI, AWS)
$180K - $200K *
Join a team that's redefining AI deployment by embedding within client operations, delivering impactful solutions in real-time. Collaborate with experts to tackle complex challenges and drive innovati...
Yesterday
Senior Forward Deployed AI Architect (GenAI, AWS)
$180K - $200K *
Lead transformative AI projects by embedding within client teams, delivering production-ready solutions that drive real business impact. Collaborate closely with stakeholders to understand needs and s...
Yesterday
$116K - $142K *
Join a team that's leveraging complex healthcare data to drive insights. You'll automate reporting, enhance client deliverables, and collaborate with business partners to elevate analytics and address...
2 weeks ago
$111K - $150K *
Lead the charge in advanced data science initiatives, guiding analytical projects of enterprise significance while mentoring a team of data scientists and ensuring methodological rigor in analyses tha...
2 weeks ago
$111K - $150K *
Lead the charge in advanced data science initiatives, guiding analytical projects of enterprise significance while mentoring junior analysts and ensuring methodological rigor in statistical modeling a...
2 weeks ago
Research Scientist, Machine Learning & Signal Processing [Technical Leadership]
$180K - $220K *
Champion innovative AI research in wearable technology, leading a team to define strategies and drive impactful projects that enhance human-computer interaction through advanced biosignal interpretati...
2 weeks ago
Research Scientist, Machine Learning & Signal Processing [Technical Leadership]
$180K - $220K *
Lead innovative AI research initiatives focused on wearable technology, driving the scientific agenda and shaping next-gen capabilities through collaboration and mentorship within a high-performing te...
2 weeks ago
$136K - $184K *
Grow your career with a dynamic team focused on advanced data science, optimizing capacity planning through machine learning and statistical modeling. Collaborate with experts to drive impactful solut...
1 week ago
$85K - $111K *
Collaborate to lead SDI3 upgrades and guide solution design processes. Foster knowledge sharing and oversee integrations while supporting GDCE development. Bring your expertise to enhance innovation a...
4 days ago
$150K - $180K *
Unlock your potential as a Senior Applied AI Engineer, leading teams to design and deliver impactful AI solutions. Drive technical excellence and mentor engineers while shaping the future of AI system...
2 days ago
Senior Machine Learning Engineer, Recommendation
$150K - $180K *
Elevate user engagement by designing and optimizing advanced search and recommendation systems. Drive content discovery and retention through innovative machine learning solutions in a dynamic, consum...
1 week ago
$110K - $130K *
Transform raw legal and medical data into impactful machine learning models. Collaborate with experts to enhance our proprietary platform using ML, NLP, and generative AI, driving measurable improveme...
1 week ago
$135K - $160K *
Join our dynamic ML team to develop and deploy cutting-edge models that enhance our proprietary claims-intelligence platform, focusing on machine learning, NLP, and generative AI to improve outcomes f...
1 week ago
$100K - $145K *
Inspire innovation in vaccine development by leveraging data science to create predictive models and monitoring tools that enhance manufacturing processes and product quality across multidisciplinary...
Today
Senior/Sr. Staff AI Infrastructure Engineer, Inference & Optimization
$169K - $351K *
Advance your career by optimizing and deploying AI models in cutting-edge infrastructures that bridge deep learning algorithms and real-time autonomous systems, ensuring ultra-low latency and operatio...
Reposted 3 weeks ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Join a team that develops AI-enabled scientific data products, shaping data strategies for drug discovery and patient safety. You'll design scalable integration frameworks, enhance data architectures...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Accelerate progress at the forefront of scientific data engineering, combining expertise in AI and data architecture to design interoperable, AI-ready data solutions that drive drug discovery and deve...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Lead the development of innovative scientific data products to enhance AI-driven drug discovery efforts, ensuring effective integration across diverse data domains to support patient safety and transl...
Reposted 1 week ago
Principal Scientist, Data Science (Data Products, Integration & Analysis)
$117K - $201K *
Shape the future of drug discovery by leading the design and implementation of AI-ready scientific data products that enhance drug development and patient safety through innovative data architectures...
Reposted 1 week ago
What does a Senior Data Scientist do?
A Senior Data Scientist uses statistics, programming, and machine learning to analyze data, develop models, and inform business or product decisions. The role often includes collaborating across teams and mentoring other data professionals.
What qualifications are common for Senior Data Scientist jobs?
Employers commonly seek substantial data science experience, proficiency in Python or R and SQL, knowledge of statistical methods and machine learning, and the ability to communicate insights. Requirements vary by company and industry.
What industries hire Senior Data Scientists?
Senior Data Scientists work in technology, financial services, healthcare, retail, consulting, and many other industries that use data to improve products, operations, or decision-making.
How can I find Senior Data Scientist jobs paying $100,000 or more?
Browse vetted Senior Data Scientist listings on Ladders and review compensation, qualifications, and responsibilities to find opportunities aligned with your experience and career goals.