Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$85K - $100K *

Join a team that's dedicated to delivering exceptional indirect tax solutions. You'll manage compliance, conduct research, and collaborate with clients across multiple jurisdictions, enhancing their t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate commercial performance by partnering with teams to translate strategies into actionable enablement. Drive measurable outcomes through effective training, tools, and continuous improvement acro...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $100K *

Champion the finance operations for Taft-Hartley benefit funds, overseeing reporting, audits, and team development. Drive process improvements and ensure accuracy in financial reporting while liaising...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $145K *

Lead the charge in shaping talent management strategies while guiding HR Business Partners. Drive performance management, succession planning, and employee engagement initiatives to enhance organizati...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead cross-functional teams in structural design and technical oversight, guiding project execution while ensuring quality and compliance across diverse construction projects to meet stringent client...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$107K - $202K *

Unlock your potential by leading complex marine and waterfront engineering projects, guiding teams through design phases, and ensuring technical excellence for public and private sector clients across...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Technical Services

$126K - $191K *

Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Advance partnerships that expand opportunities for youth by securing multi-million-dollar commitments. Lead outreach to C-suite executives, develop proposals, and drive fundraising efforts to support...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$112K - $128K *

Drive business development for large-scale podcast and broadcast campaigns, fostering client relationships and achieving revenue growth. Collaborate with cross-functional teams to deliver innovative a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$125K - $150K *

Join a dynamic team as you lead corporate accounting operations, driving financial reporting, audits, and process improvements. Shape the future of accounting through strategic leadership and innovati...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$151K - $226K *

Lead the charge in managing observational research projects, ensuring operational excellence and cross-functional collaboration. Drive timely delivery of high-quality Real-World Evidence to support cl...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Empower innovation in mobile advertising by leveraging expertise in measurement and fraud mitigation. Collaborate with stakeholders to enhance adtech solutions and navigate the evolving landscape of d...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$150K - $180K *

Drive strategic growth by leading business development and sales operations, optimizing RFP processes, and enhancing performance metrics. Collaborate across teams to ensure alignment and improve outco...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $180K *

Transform enterprise sales in the public sector by driving automation solutions, building strategic relationships, and generating new business opportunities while collaborating with partners and stake...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $140K *

Lead the charge in optimizing Workday Compensation for a global workforce. Collaborate with stakeholders to ensure accurate configuration and alignment with organizational strategies across multiple c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $155K *

Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$90K - $110K *

Unlock potential by joining a dynamic team as a Workers’ Compensation Claims Specialist. Leverage your expertise to investigate, resolve, and manage claims while ensuring compliance and delivering exc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $400K *

Elevate your career by leading strategic compensation advisory services for multinational clients. Drive growth, deliver innovative solutions, and mentor a talented team while shaping the future of wo...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leveraging your Salesforce expertise to design, build, and review secure, scalable solutions. Collaborate with clients and teams to ensure seamless integrations and effective deliv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $225K *

Lead the charge in driving business growth for critical infrastructure in the NY/NJ region. Collaborate with local leaders to enhance market share, develop strategic alliances, and implement customer...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $95K *

Empower your career by leading engineering projects, coordinating teams, and enhancing technical expertise while ensuring compliance with safety standards and managing project performance effectively...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$274K - $356K *

Transform the actuarial function by leading AI-enabled workflows and modern analytics, improving decision-making and fostering collaboration across Finance, Clinical, and Growth teams while ensuring c...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$158K - $188K *

Join a team that's dedicated to driving growth in commercial banking by managing complex relationships in the AEC sector. Leverage your expertise to deliver tailored financial strategies and foster lo...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$158K - $188K *

Drive strategic growth by managing complex commercial banking relationships in the AEC sector. Leverage industry expertise to deliver tailored financial solutions and foster long-term partnerships, en...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.