Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$143K - $179K *
Analyze customer experiences to drive retention strategies and enhance satisfaction. Collaborate across teams to shape data-driven decisions, develop metrics, and prioritize analytics initiatives that...
Yesterday
$164K - $245K *
Transform vendor legal operations by leading negotiations and enhancing processes. Collaborate with cross-functional teams to streamline agreements and empower stakeholders, ensuring efficiency and sc...
1 week ago
Senior - Administrative Assistant
$63K - $111K *
Join a team that's dedicated to providing top-notch administrative support to program leadership and project personnel, ensuring smooth operations and effective communication across multidisciplinary...
1 week ago
Field Medical Director, Breast and Gynecological Cancers (MD)
$230K - $384K *
Shape the future of oncology by leading medical strategy and engagement across diverse customer segments. Collaborate with internal teams to deliver impactful medical insights and support clinical ini...
Reposted 1 week ago
$115K - $135K *
Drive your career forward by managing a diverse portfolio of high-net-worth clients, delivering expert tax preparation and advisory services while collaborating with financial advisors to maximize cli...
1 week ago
$95K - $158K *
Champion high-availability database platforms, driving automation and cloud modernization. Collaborate with engineering teams to enhance reliability and performance across hybrid environments, ensurin...
3 weeks ago
$220K - $250K *
Unlock potential by driving strategic partner relationships and collaborating across teams to enhance solution development, enabling partners to achieve measurable outcomes while promoting business gr...
Reposted 3 weeks ago
$85K - $105K *
Champion exceptional client relationships by delivering innovative solutions, managing campaigns, and driving strategic marketing goals to enhance performance and satisfaction for high-value clients i...
Reposted 3 days ago
Practice Innovation Attorney (Intellectual Property)
$155K - $317K *
Elevate legal service delivery by driving innovation and optimizing workflows. Collaborate with attorneys and business teams to implement AI-enabled solutions, enhance knowledge management, and improv...
1 week ago
$125K - $150K *
Transform financial operations by leading accounting, reporting, and FP&A. Drive efficiency through AI integration, manage audits, and build scalable processes while supporting strategic growth initia...
Today
$100K - $140K *
Champion the proposal process by leading submissions, coordinating resources, and ensuring strategic alignment. Drive improvements in proposal development while fostering collaboration across teams to...
Reposted 1 week ago
Practice Innovation Attorney (Intellectual Property)
$155K - $317K *
Champion innovative legal service delivery by enhancing workflows, knowledge management, and technology adoption. Collaborate with attorneys and business teams to implement scalable solutions that imp...
1 week ago
Practice Innovation Attorney (Intellectual Property)
$155K - $317K *
Elevate legal service delivery by driving innovation and optimizing workflows. Collaborate with attorneys and business teams to implement AI-enabled solutions, enhance knowledge management, and improv...
1 week ago
Practice Innovation Attorney (Intellectual Property)
$155K - $317K *
Transform legal service delivery by optimizing workflows, enhancing knowledge management, and implementing innovative technology solutions. Collaborate with attorneys and business teams to drive effic...
1 week ago
$110K - $130K *
Join a team that's committed to enhancing environmental, health, and safety standards across multiple sites. Lead audits, provide hands-on support, and drive compliance initiatives while collaborating...
6 days ago
$121K - $148K *
Lead the credit origination process by analyzing complex financial data, preparing detailed reports, and guiding teams to ensure compliance and profitability. Collaborate with stakeholders to enhance...
4 weeks ago
Senior Director, Late Oncology
$230K - $345K *
Shape the future of late-stage oncology clinical trials by leading strategic initiatives, ensuring operational excellence, and fostering cross-functional partnerships to drive successful trial executi...
5 days ago
Customer Success Manager, Enterprise
$90K - $125K *
Deliver exceptional customer success through effective engagement, relationship-building, and proactive problem-solving for complex district implementations. Collaborate with teams to ensure portfolio...
Reposted 1 week ago
Advisory Enterprise Account Executive
$150K - $180K *
Unlock potential by driving transformational sales initiatives and cultivating strategic partnerships. Engage with C-suite stakeholders to shape enterprise revenue and influence market direction throu...
3 weeks ago
Medical Strategy Associate Director
$191K - $238K *
Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...
5 days ago
Senior Partner Marketing Manager
$110K - $130K *
Empower partner marketing initiatives by developing strategies that drive qualified referrals and pipeline growth across diverse partner ecosystems in North America and EMEA. Collaborate with stakehol...
Yesterday
$110K - $130K *
Unlock compensation strategies by partnering with teams to analyze, model, and deliver data-driven solutions. Drive benchmarking, job architecture, and annual comp cycles to ensure equitable pay pract...
3 weeks ago
Senior Estimator/Project Manager-Heavy Civil Construction
$100K - $150K *
Join a team that's shaping the future of heavy civil construction by managing complex projects from estimation to execution. Leverage your expertise to deliver high-quality results while collaborating...
Reposted today
Senior Channel Specialist - Paid Search
$80K - $90K *
Grow your career with a robust role in executing paid search campaigns while driving performance in a multi-brand environment. Join a dynamic team committed to optimizing revenue through strategic ad...
Reposted today
Sales Manager, Commercial Claims
$89K - $166K *
Help us drive growth as you lead a team focusing on Commercial Claims, enhancing key relationships and achieving sales objectives while managing strategic accounts and fostering talent development wit...
Reposted today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.