Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Professional Services Consultant
$95K - $115K *
Engage with clients to transform complex Enterprise Architecture needs into actionable solutions. Manage implementation workstreams, ensuring effective onboarding and training while fostering strong r...
3 weeks ago
Senior Systems & Security Engineer
$110K - $130K *
Empower our IT environment by enhancing security and reliability through hands-on systems engineering, cybersecurity, and incident response. Collaborate across teams to design, implement, and manage s...
5 days ago
Field Supervision Director - Primary
$110K - $130K *
Oversee compliance and risk management for branch teams, ensuring adherence to regulatory standards. Collaborate with leadership to enhance compliance culture and support client-focused solutions whil...
1 week ago
$110K - $130K *
Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...
6 days ago
Senior Manager, Compliance Advisory & Change Management
$172K - $238K *
Shape compliance strategies by operationalizing key frameworks, guiding stakeholders, and ensuring adherence to regulations. Collaborate across teams to enhance risk management and support product com...
Reposted 2 weeks ago
$120K - $145K *
Transform enterprise learning by leading a team to design impactful solutions. Drive employee development, align training with business goals, and optimize learning technologies for enhanced performan...
Reposted 1 week ago
Specialty (SBA) Credit Underwriter II/Specialty (SBA) Sr. Credit Underwriter
$91K - $150K *
Empower small businesses by underwriting and approving SBA credit requests. Utilize strong credit skills to analyze financial data, ensure compliance, and collaborate with teams to deliver effective c...
1 week ago
$120K - $150K *
Join a dynamic team to provide expert legal services in labor and employment law. Leverage your experience in litigation and counseling while engaging with clients and agencies in a fast-paced environ...
2 weeks ago
$85K - $141K *
Analyze loan files to ensure compliance with SBA requirements, identifying risks and deficiencies. Collaborate with lenders to clarify documentation and prepare detailed reports, maintaining high stan...
6 days ago
Grant Administration Consultant, Manager
$99K - $232K *
Manage grant administration workstreams in health services, leading teams and enhancing client service delivery. Drive process improvements, oversee compliance, and support project execution while coa...
2 weeks ago
Director of Business Development
$125K - $150K *
Drive growth by cultivating owner relationships and securing management agreements in multifamily and hospitality sectors, enhancing market presence and collaboration with internal teams...
Reposted 2 weeks ago
$80K - $95K *
Transform talent acquisition by leading innovative recruitment strategies, ensuring a seamless candidate experience, and collaborating with stakeholders to deliver diverse talent pools that meet uniqu...
5 days ago
$127K - $157K *
Champion medical affairs for Photofrin and PDT, engaging with healthcare professionals and leading initiatives. This role offers autonomy and visibility, ideal for experienced Medical Affairs professi...
3 days ago
$120K - $140K *
Join a team that's transforming tax research by leveraging AI technology. As a key member, you'll design innovative tax workflows, collaborate with clients, and shape product development, all while en...
4 days ago
$175K - $210K *
Lead the charge in overseeing M&A tax strategies, providing expert guidance on domestic and international deals while mentoring a dynamic team to exceed client expectations and drive practice growth...
Reposted today
Construction Project Risk Consultant (Full-Time)
$94K - $114K *
Support project risk management initiatives across various sectors, collaborating with stakeholders to identify, analyze, and mitigate risks. Lead qualitative and quantitative assessments to enhance p...
6 days ago
$102K - $180K *
Transform enterprise partnerships by driving account growth, fostering relationships, and optimizing sales processes. Collaborate with internal teams, lead post-sales management, and utilize data insi...
Reposted today
$80K - $95K *
Transform complex cybersecurity narratives into engaging content that captivates audiences across various formats. Collaborate with cross-functional teams to enhance brand storytelling and drive conve...
3 weeks ago
$110K - $130K *
Drive compliance and policy excellence as a Senior HR Advisor, overseeing employee relations, complex cases, and immigration. Collaborate globally to harmonize policies during acquisition, leveraging...
5 days ago
Senior Director, Medical Director, Lung Cancer and Early Pipeline
$268K - $402K *
Drive strategic medical affairs initiatives in lung cancer, leading evidence generation and cross-functional collaboration to enhance product development and patient outcomes in oncology...
Yesterday
$95K - $115K *
Join a team that's dedicated to optimizing software systems and applications. Leverage your expertise in application administration to enhance performance, ensure security, and support users across mu...
2 weeks ago
$150K - $180K *
Engage in strategic leadership to enhance wholesale market placements, ensuring optimal coverage and pricing. Oversee national partnerships and market execution while driving team performance and resp...
Reposted 6 days ago
Managing Director - Market Development & Revenue Growth (Insurance Growth Platforms)
$180K - $220K *
Lead the charge in driving growth across insurance platforms by building strategic alliances, developing executive relationships, and executing market strategies to enhance revenue and expand opportun...
2 weeks ago
Senior Portfolio Manager - Commerce Trust
$137K - $214K *
Optimize client investment portfolios by establishing objectives, asset allocation, and performance reporting. Collaborate with teams to ensure tailored financial strategies and proactive client servi...
2 weeks ago
Senior Portfolio Manager - Commerce Trust
$137K - $214K *
Join a team that's dedicated to managing client portfolios, establishing investment objectives, and delivering tailored financial solutions while collaborating with seasoned professionals to enhance c...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.