Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$80K - $95K *

Unlock your potential as you lead critical bat surveys, navigate regulatory landscapes, and support renewable energy projects. Your expertise will protect endangered species while driving sustainable...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $175K *

Transform the future of nonprofit investment strategies by leading client engagement, business development, and team coordination. Drive growth and enhance service delivery for a diverse portfolio of...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by driving strategic partnerships and business growth. As a Senior Leader, you'll cultivate relationships, identify opportunities, and collaborate across teams to transform ideas into...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$162K - $192K *

Lead strategic sales initiatives and manage P&L for MCC, driving growth through vendor contracts and financial oversight while executing the Commercial Strategic Plan and ensuring alignment with site...

Today

  •   8 - 10 years exp.  •   Food & Beverages

$150K - $170K *

Lead strategic contracts management, overseeing development and negotiation of federal contracts. Collaborate cross-functionally to ensure compliance and risk management while driving organizational g...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$115K - $125K *

Transform pricing strategies by developing financial models and analytics to support attorneys. Collaborate across teams to enhance profitability and create innovative budget solutions while ensuring...

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$115K - $125K *

Unlock potential by developing financial models and analytics to support pricing strategies. Collaborate with attorneys to enhance profitability through innovative pricing arrangements and comprehensi...

5 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Lead document review projects by optimizing workflows and technology. Collaborate with counsel and internal teams to ensure quality and efficiency in deliverables, driving down costs while enhancing a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $100K *

Drive the success of multiple claims teams by supervising operations, providing technical guidance, and ensuring quality standards. Collaborate with management to enhance processes and maintain strong...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $95K *

Unlock potential by managing HR systems and analytics, ensuring data integrity and compliance. Collaborate with cross-functional teams to optimize HR technology and reporting, driving strategic insigh...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Join a dynamic team as a subject-matter expert, providing strategic guidance and bespoke insurance solutions for complex multi-generational family offices, while influencing product development and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$266K - $372K *

Join a dynamic Ads Legal team to provide strategic legal guidance on product initiatives, ensuring compliance with evolving regulations while collaborating across functions to drive innovation in a fa...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Media

$125K - $148K *

Drive strategic partner acquisition by generating new business opportunities in workforce payments, focusing on payroll and pension. Collaborate cross-functionally to build a robust pipeline and lead...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$143K - $200K *

Innovate solutions as a Senior Appian Developer, tackling complex BPM challenges. Collaborate with teams to design, implement, and optimize high-performance applications while mentoring junior develop...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$112K - $169K *

Transform enterprise trial experiences by leading tailored execution of Samsara technology. Collaborate across teams to drive success in customer trials, ensuring impactful outcomes that enhance sales...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Build and lead a scalable U.S. service organization for battery energy storage systems, ensuring customer satisfaction and operational excellence throughout the post-sale lifecycle, from commissioning...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$71K - $119K *

Drive customer success by leveraging expertise in intellectual property solutions, enhancing product adoption, and delivering exceptional experiences through strategic engagement and training initiati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$140K - $200K *

Transform decision-making by leading financial planning and analytics efforts. Oversee reporting, data governance, and deliver actionable insights for stakeholders to drive performance, profitability...

Reposted yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$200K - $232K *

Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Join us in shaping innovative partner programs aimed at enhancing legal collaboration. This strategic role demands creativity and leadership, managing bar association relations to propel growth and su...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$82K - $106K *

Advance your career by leading B2B paid search strategies and driving client growth through data-driven insights, performance management, and effective cross-team collaboration in a dynamic marketing...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $200K *

Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$300K *

Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the growth of strategic partner relationships, driving revenue through effective collaboration and pipeline management. Own a portfolio of partners, ensuring alignment and execution of joint busi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$93K - $137K *

Join a dynamic team to enhance partner relationships, drive operational excellence, and foster business growth through strategic onboarding and support initiatives. Leverage your insurance expertise t...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.