Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$125K - $150K *

Lead complex contract strategy and execution, enhancing scalable systems to support sales and growth. Collaborate across teams to align contracts with business needs while addressing immediate challen...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the success of Abacum implementation projects, managing end-to-end delivery while collaborating with sales and partners to ensure client satisfaction and value realization on the platform...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$82K - $86K *

Lead the charge in managing complex liability claims, ensuring thorough investigations, evaluations, and negotiations. Collaborate with clients and legal teams to achieve optimal resolutions while adh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $150K *

Reimagine the services landscape by optimizing the sales and delivery of professional services. In this influential role, collaborate cross-functionally to enhance proposal creation, streamline operat...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $106K *

Optimize legal operations by providing expert advice on contracts, collaborating with teams, and ensuring compliance. Leverage your transactional law experience to streamline processes and support the...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$132K - $182K *

Shape the future of MSSP partner agreements by modernizing frameworks, guiding negotiations, and collaborating with cross-functional teams to enhance revenue strategies and streamline contract process...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Manage diverse legal matters in a dynamic industrial environment, providing strategic support across commercial contracts, regulatory compliance, and corporate governance while collaborating closely w...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Shape the future of sales enablement by building a robust function from the ground up. Drive onboarding, training, and process adoption while leveraging analytics to enhance productivity and CRM usage...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $100K *

Shape the future of semiconductor advisory by leading transformative projects, driving multimillion-dollar sales, and mentoring a dynamic team of consultants to deliver innovative solutions in supply...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$57K - $178K *

Unlock your potential by managing estate administration and tax matters, supporting attorneys in trust funding, document preparation, and client relations. Bring your expertise to a dynamic team focus...

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$57K - $178K *

Join a dynamic team to manage estate administration, prepare tax returns, and support attorneys in complex trusts and estates matters, ensuring exceptional client service and meticulous attention to d...

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$64K - $125K *

Take ownership of estate administration by supporting attorneys in managing estates, preparing tax returns, and ensuring compliance with legal requirements while maintaining client relationships and m...

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$57K - $178K *

Champion the administration of estates and trusts, ensuring compliance and accuracy in tax filings while managing client relationships and case documentation. Leverage your expertise to deliver except...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$64K - $125K *

Elevate your career by managing estate administration and tax matters, supporting attorneys in complex trust and estate processes. Collaborate with clients and financial advisors while ensuring meticu...

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join a team that's dedicated to delivering innovative eDiscovery solutions. Collaborate with cross-functional teams to manage client relationships, oversee project execution, and provide expert guidan...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $115K *

Partner with us to enhance client engagement and product success by leveraging your analytical skills and industry insights. Collaborate cross-functionally to drive improvements and support user adopt...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$75K - $140K *

Engage with Midsize Law Firms to drive sales growth by prospecting, setting appointments, and supporting existing clients. This role offers a pathway to a full-time sales position with territory owner...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Elevate the technical architecture vision and execution across a product portfolio, driving the transition to a scalable, cloud-native SaaS environment while integrating AI, data, and security. Collab...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Business Services

$190K - $220K *

Lead the charge in providing strategic legal guidance on complex commercial contracts, enhancing efficiency and compliance while collaborating with cross-functional teams to drive business growth and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $190K *

Empower innovation at the intersection of technology and law. Guide product, engineering, and compliance teams in navigating regulatory landscapes and mitigating risks related to AI and machine learni...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$165K - $190K *

Unlock potential by leading licensing and business contracts, providing strategic legal support across teams, and managing a talented unit to ensure effective contract governance and compliance in a d...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$122K *

Champion clinical excellence by leading large teams, ensuring strategic alignment, and driving patient recruitment while mitigating risks in clinical operations for successful study execution...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage and enhance enterprise applications, leading a team to ensure optimal performance, support, and user satisfaction while collaborating with IT and vendors to drive improvements and maintain docu...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Manage and enhance enterprise applications, leading a team to ensure optimal performance, support, and user satisfaction while collaborating with IT and vendors to drive improvements and maintain docu...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Shape the future of talent acquisition by driving full life cycle recruitment for financial advisors. Collaborate with leadership and engage candidates to build a diverse talent pipeline while trackin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.