Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$143K - $230K *

Elevate your career by driving sales growth in Governance, Risk, and Compliance solutions. Collaborate with executive-level clients to identify needs, present tailored solutions, and close deals, all...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Advance business growth by building strategic relationships and identifying client needs. Drive sales initiatives and ensure seamless implementation of client programs while meeting profit margins and...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $195K *

Engage with healthcare payer clients to architect integrated solutions, driving revenue growth through strategic discovery, technical leadership, and value engineering. Collaborate across teams to del...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$139K - $157K *

Transform client partnerships by leading innovative commerce strategies across major retail platforms. Drive growth through integrated marketing, operational excellence, and creative solutions, ensuri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$75K - $175K *

Advance application security initiatives by leading manual code reviews, penetration tests, and threat modeling. Work closely with clients to strengthen their secure development processes, delivering...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $108K *

Champion compliance excellence by ensuring adherence to state and federal laws. Collaborate with teams to support program requirements and conduct audits, fostering a culture of accountability and int...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Accelerate business growth by leading strategic initiatives to secure new construction opportunities. Build strong relationships with industry partners while collaborating with internal teams to enhan...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$160K - $200K *

Lead and shape a high-performing Security Engineering and Operations team, driving proactive threat management and strategic engineering initiatives across North America while enhancing operational ef...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Media

$80K - $95K *

Inspire a community by leading a dedicated team, enhancing resident care, and driving growth through strategic initiatives and operational excellence. Foster relationships and ensure a positive enviro...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$107K - $188K *

Unlock potential by managing high-profile accounts and driving sales growth through strategic planning and complex negotiations. Leverage your expertise to develop tailored solutions and exceed revenu...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$195K - $230K *

Drive growth by leading go-to-market strategies for TMC partnerships, building and executing plans from the ground up. Collaborate cross-functionally to influence product development and represent the...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $160K *

Take ownership of strategic client relationships, driving retention and growth while leading negotiations and fostering executive partnerships. Collaborate cross-functionally to deliver exceptional cl...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $110K *

Lead and enhance the Workers' Compensation claims team, ensuring compliance, quality handling, and client satisfaction while mentoring staff and driving operational efficiency across diverse caseloads...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate compliance standards by enhancing AML and OFAC programs. Collaborate with cross-functional teams to mitigate financial crime risks while ensuring adherence to regulatory requirements and lever...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$102K - $176K *

Lead the charge in strategic sourcing negotiations, managing contracts and vendor relationships to optimize operational efficiency and compliance with financial objectives. Collaborate across teams to...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$102K - $176K *

Transform procurement strategies by leading vendor negotiations for contracts, ensuring compliance and operational alignment. Collaborate cross-functionally to optimize sourcing processes and enhance...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$102K - $176K *

Unlock potential by leading vendor sourcing negotiations and contract management, ensuring compliance with finance requirements while collaborating with internal partners to enhance operational effici...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$102K - $176K *

Innovate within our finance team by leading vendor sourcing negotiations for projects with an annual spend up to $500K. Collaborate with internal leaders to ensure compliance and improve operational p...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$134K - $162K *

Lead the charge in advancing clinical adoption and workflow optimization for radiopharmaceutical products. Collaborate cross-functionally to ensure safe, compliant practices while building strategic r...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$179K - $190K *

Shape the future of payroll and HR services by leading strategic initiatives, optimizing operations, and ensuring compliance across the employee lifecycle. Drive excellence in service delivery while f...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Transform your career by leading full-cycle recruiting for GTM roles. Collaborate with executives to define hiring standards, build strong talent pipelines, and drive strategic hiring initiatives in a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform project execution by leading complex construction initiatives, fostering client relationships, and mentoring future leaders. Drive financial performance and operational excellence while ensu...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$102K - $176K *

Analyze and negotiate vendor contracts, ensuring compliance and best practices across departments. Collaborate with internal leaders and external partners to enhance operational efficiency while manag...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.