Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$180K - $220K *

Elevate your career by leading global marketing strategies that drive demand generation, enhance brand positioning, and support revenue growth in the healthcare technology sector. Collaborate with cro...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Deliver scalable backend services and APIs for scholarly content, enhancing search and discovery systems. Collaborate with cross-functional teams to optimize performance and reliability while integrat...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Empower your career by leading a dynamic sales team, building client relationships, and implementing proven strategies to drive success in the insurance industry while enjoying flexible scheduling and...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $275K *

Unlock potential by defining and driving the technical vision and product strategy for Next-Gen SIEM and Log Management products, ensuring alignment with market needs and customer motivations while fo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$106K - $120K *

Transform enrollment operations by leading a dynamic team, optimizing processes, and driving performance improvements across multiple companies to enhance efficiency and compliance in a remote environ...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $88K *

Champion compliance by reviewing and approving advertising materials, ensuring adherence to regulatory standards while collaborating with stakeholders to mitigate risks and enhance practices for quali...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$86K - $130K *

Drive pipeline safety compliance by analyzing regulations and ensuring adherence to federal and state standards. Collaborate with teams to develop training, monitor compliance, and prepare for inspect...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $120K *

Lead a diverse portfolio of clients as a Tax Manager, overseeing compliance and planning while mentoring your team. Enjoy autonomy in client relationships and contribute to a culture of high-quality s...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$138K - $190K *

Advance solutions in behavioral health by leveraging technical expertise to drive sales success. Collaborate with teams to deliver tailored demonstrations, support RFPs, and align strategies with clie...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $115K *

Empower a high-performing team to enhance customer trial experiences, driving strategic initiatives and fostering collaboration. Lead with data-driven insights to optimize processes and ensure excepti...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $115K *

Champion integrated media strategies for pharmaceutical clients, driving engagement and measurable outcomes. Lead cross-functional teams to develop innovative solutions that address complex healthcare...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $120K *

Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Partner with us to tackle complex operational challenges, driving impactful initiatives across our portfolio. This role offers hands-on experience and growth opportunities, ideal for future leaders ea...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $115K *

Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$109K - $175K *

Lead the charge in financial planning and analysis, driving accurate forecasts, budgets, and financial insights to support business objectives and enhance decision-making across departments...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $172K *

Shape the future of cash management by enhancing forecasting capabilities and providing critical insights for strategic decision-making, operational planning, and capital allocation in a dynamic envir...

RemoteRemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Join a team that's redefining cybersecurity by leveraging AI to enhance defense strategies. Engage with customers across the Americas, translating complex concepts into actionable insights while drivi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$250K - $280K *

Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$137K - $186K *

Join our dynamic FinTech team as a Senior Product Manager, leading strategy, and execution to shape payment solutions. Leverage your product management expertise to drive growth and enhance customer e...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$125K - $145K *

Unlock potential by bridging business needs with technical solutions. Collaborate with stakeholders to define requirements, manage product backlogs, and ensure successful delivery of ServiceNow capabi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Shape and elevate business operations and account management, driving resource optimization and client satisfaction. Collaborate with leadership to enhance project delivery and expand client relations...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage with top-tier partners to define and execute innovative co-marketing strategies that amplify AI-driven growth. Oversee the entire partner marketing roadmap, ensuring measurable impact on pipeli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by leading tailored service solutions that drive client success. Collaborate with stakeholders to strategize and execute sales plans, ensuring exceptional engagement and delivering va...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to optimizing software order fulfillment and licensing. In this senior role, you'll analyze complex configurations, drive issue resolution, and enhance operational process...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$90K - $100K *

Transform the future of a landmark redevelopment project by leading strategic initiatives, managing operations, and fostering tenant relationships to drive financial performance and operational excell...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.