Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$175K - $220K *

Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$74K - $118K *

Elevate compliance standards by leading oversight initiatives, managing complex projects, and collaborating across teams to ensure regulatory adherence and effective governance in a dynamic environmen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Grow your career with a dynamic team focused on enhancing knowledge management. Lead strategic initiatives, develop talent, and shape self-service experiences while collaborating across departments to...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$67K - $95K *

Champion business growth by driving sales through strategic prospecting and consultative selling. Build and manage a diverse client portfolio, leveraging technology and relationships to exceed quotas...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Empower enterprise clients by driving product adoption and success. As a key advisor, you'll manage relationships, develop strategic roadmaps, and ensure customer satisfaction while collaborating with...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $235K *

Join a team that's redefining business processes through digital transformation. Lead cross-functional initiatives, ensuring scalable and standardized practices that align with strategic goals while f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $321K *

Optimize enterprise risk management by leading independence assessments and regulatory compliance efforts. Guide teams through complex challenges, ensuring accountability and continuous improvement wh...

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$141K - $234K *

Lead a team of Advisory consultants to enhance healthcare performance by managing client engagements, ensuring project quality, and fostering strong relationships. Oversee deliverables, drive profitab...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$58K - $107K *

Manage and oversee Short-Term Disability claims and leave requests, ensuring compliance with regulations while supporting employees' return-to-work strategies through effective case management and com...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $245K *

Lead the charge in developing and empowering a high-performing sales team. Foster a strong team culture while driving improvement and accountability in a rapidly changing environment, leveraging data...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$92K - $167K *

Drive compliance and contractor support in contracting standards, regulatory adherence, and policy execution. Work collaboratively across departments to provide strategic guidance, ensuring alignment...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $166K *

Unlock potential by leading the development of vibrant senior living communities. Oversee project lifecycles from concept to occupancy, ensuring alignment with market needs and operational goals while...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$114K - $210K *

Champion the development of regulatory documents for global submissions, managing timelines and cross-functional collaboration to ensure quality and compliance with industry standards while mentoring...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$77K - $147K *

Join a dynamic team as a Senior CX Manager, driving strategic customer success through technical enablement and relationship management. Leverage your expertise to lead complex initiatives and foster...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Champion client success by managing a diverse portfolio, ensuring strategic alignment and operational excellence. Collaborate with teams to enhance service delivery and foster strong client relationsh...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$65K - $130K *

Contribute to clinical trial success by leading risk management and central monitoring activities. Collaborate with cross-functional teams to ensure compliance with ICH GCP guidelines and enhance qual...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Engage in leading a dynamic team dedicated to delivering top-notch offensive security engagements, ensuring delivery quality and client satisfaction, while collaborating with sales to expand accounts...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$116K *

Lead site activation efforts by coordinating with cross-functional teams to ensure timely and quality delivery of clinical projects. Drive strategic initiatives and mitigate risks while enhancing comm...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Pioneer innovative solutions for state government clients by leading IV&V projects, providing expert guidance on system implementations, and ensuring project success through effective communication an...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $115K *

Join a dynamic team as a Senior Project Planner, driving financial health and vendor coordination across multiple brands while ensuring project success through strategic planning and effective communi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$228K - $342K *

Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $200K *

The Licensed Life Insurance Sales Agent will guide customers through the life insurance buying process, educating them on products and ensuring a transparent experience. This role involves engaging wi...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$80K *

Empower clients by managing complex care needs through remote case management, ensuring access to high-quality treatment and support. Collaborate with multidisciplinary teams to enhance client engagem...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$115K - $135K *

Join a team that's driving enterprise growth by identifying new business opportunities and forming strategic relationships. You'll navigate complex sales cycles and engage with senior leaders to tailo...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.