Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Drive innovative solutions by leveraging data analytics and strategic counsel to enhance client performance. Collaborate with high-performing teams to deliver tailored insights for transformational ev...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Deliver impactful project leadership by guiding cross-functional teams through all phases of clinical research, ensuring compliance, effective communication, and timely project milestones that enhance...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$116K *

Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $290K *

Join a team that's redefining strategic research by tackling complex, ambiguous challenges. Collaborate with product, design, and engineering leaders to shape impactful insights that drive business de...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$85K - $100K *

Join us in leading hospice services by developing strategic plans, ensuring compliance, and fostering relationships to enhance patient care and business growth. Drive operational excellence while mana...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $130K *

Reimagine tax management by joining a dynamic team focused on high-net-worth clients. Collaborate with financial advisors to deliver exceptional service, tackle complex tax issues, and thrive in a fas...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $267K *

Lead the evolution of enterprise technology architecture, aligning business strategies with architectural principles and standards. Oversee governance frameworks and collaborate across teams to ensure...

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's shaping the future of claims management for Non-Profits. Lead and mentor a skilled team, providing strategic direction on complex claims while ensuring exceptional service and compl...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $97K *

Unlock potential by conducting in-depth equity research, delivering actionable insights, and collaborating with a dynamic team to support institutional investors and advisors in making informed financ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $165K *

Empower growth by leading strategic partnerships in the insurance sector. Drive revenue and client retention through innovative solutions and deep industry insights, while managing complex sales cycle...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$91K - $109K *

Lead the charge in maintaining financial integrity by overseeing accounting operations, ensuring compliance with nonprofit standards, and managing audits. Collaborate with finance leadership to produc...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Lead the charge in transformative initiatives that enhance efficiency and innovation across global accounting operations. Collaborate with senior leaders to drive measurable improvements and optimize...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$40K - $200K *

Join a dynamic team to drive business growth through consultative sales, building lasting client relationships, and delivering innovative payment solutions. This role offers uncapped earnings and oppo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $161K *

Champion complex partnership tax strategies, providing technical guidance and solutions. Collaborate with national teams to analyze federal tax issues, develop training, and enhance consulting practic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$96K - $161K *

Elevate your career by leveraging your underwriting expertise to assess complex mortality risks. Collaborate with industry professionals, enhance underwriting practices, and maintain strong relationsh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $175K *

Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Transform the future of go-to-market strategy by leading cross-functional teams, driving execution governance, and shaping long-range plans to achieve growth objectives in a dynamic, global environmen...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Food & Beverages

$67K - $128K *

Join a team that's redefining assurance in banking and specialty finance. Contribute to client service delivery, maintain quality standards, and execute core functions while supporting team objectives...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in managing premium client portfolios, guiding a skilled team to foster relationships and develop growth strategies across various verticals, maximizing both client success and agency...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$101K - $132K *

Elevate your career by driving strategic partnerships with leading cloud providers. Collaborate across teams to enhance revenue growth and client satisfaction while managing key partner relationships...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $135K *

Transform the insurance landscape by leading product innovation and development initiatives, enhancing personal Property products to meet member needs and drive profitable growth while ensuring market...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate financial operations by overseeing budgeting, forecasting, and reporting. Collaborate with leadership to drive strategic insights and strengthen compliance while mentoring a dynamic finance te...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Drive regulatory strategy across major programs, leading high-impact submissions and authority engagement. Collaborate with cross-functional teams to optimize clinical development and ensure complianc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Lead the Nursing Department to ensure quality care and compliance, overseeing staff, policies, and performance improvement initiatives while fostering a compassionate environment for Guests...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$165K - $200K *

Join us in enhancing client satisfaction and service delivery as a Principal Consultant. Leverage your expertise to lead projects, mentor teams, and drive continuous improvement across multiple accoun...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.