Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$140K - $210K *

Lead the charge in delivering innovative integration solutions for clients in the State & Local Government sector. Collaborate with project teams to design, develop, and implement effective Workday in...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Consumer Technology

$125K - $150K *

Optimize reimbursement strategies and regulatory compliance by leading analysis, developing policies, and mentoring teams. Drive operational excellence and foster relationships with stakeholders to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Join a team that's driving impactful client strategies in digital marketing. As a Supervisor, you'll lead a dynamic team, manage client relationships, and oversee integrated campaigns across omnichann...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$127K - $171K *

Elevate marketing strategies by connecting customer insights and business goals. Develop compelling messaging and content that simplifies complex products, driving engagement and alignment across team...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Transform enterprise strategies into actionable roadmaps, guiding clients through comprehensive change initiatives. Collaborate with stakeholders to drive alignment, enhance performance, and ensure su...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$134K - $241K *

Champion trade compliance by leading a team to ensure adherence to regulations, manage risks, and implement strategies that align with business goals while fostering a culture of integrity and innovat...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$115K - $125K *

Grow your career with a dynamic role focused on client relationships, strategic account management, and operational excellence. Collaborate with cross-functional teams to ensure client satisfaction an...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$88K - $105K *

Transform client marketing strategies by leading integrated campaigns, translating data into actionable insights, and driving measurable results. Collaborate cross-functionally while mentoring junior...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$242K - $290K *

Empower strategic partnerships by managing alliances, driving collaboration, and ensuring alignment with organizational goals. Leverage your expertise to foster trust and deliver impactful outcomes in...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $181K *

Manage and grow a diverse portfolio of health plan customers, driving satisfaction and retention. Build strategic relationships, navigate complex payor landscapes, and champion clinical outcomes to de...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $175K *

Unlock potential by leading treasury operations, managing liquidity, and optimizing investment strategies. Drive risk management and compliance while fostering banking relationships in a dynamic finte...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $90K *

Transform partner engagement by activating and growing low-performing distribution partners. Drive adoption and integration through training and outreach, fostering strong relationships to enhance pro...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $106K *

Join a team that leads labor compliance for utility scale construction projects, ensuring adherence to complex federal, state, and local regulations. This role offers autonomy in compliance oversight...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$370K - $415K *

Unlock potential by leading Affirm's global legal strategy across Product, Regulatory, and Litigation teams. Collaborate with executives to drive innovation while managing complex legal risks in the c...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Finance & Insurance

$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Engage with C-suite leaders to drive strategic sales for a compliance platform. Lead full sales cycles, develop account strategies, and leverage AI tools to enhance client relationships and achieve re...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $125K *

Reimagine the broking landscape by leading complex placements, mentoring staff, and fostering strong relationships with clients and insurers. Drive optimal outcomes through innovative solutions and ef...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$165K - $205K *

Lead the charge in cybersecurity governance and risk management consulting. Drive client engagements, develop security frameworks, and mentor teams while ensuring alignment with industry standards and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$95K - $115K *

Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$137K - $186K *

Unlock potential by leading cross-functional teams to deliver platform features that enhance global market capabilities. Drive localization efforts and ensure seamless integration across diverse regio...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$200K - $450K *

Drive independent credit review and risk management for all counterparties, ensuring compliance and security across diverse financial entities. Collaborate with cross-functional teams to uphold rigoro...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $175K *

Accelerate progress at our company by driving growth within existing accounts. Leverage strategic relationships and insights to enhance customer success and maximize product adoption, ensuring long-te...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $140K *

Join a dynamic team to enhance cybersecurity programs, engage with clients, and deliver strategic advisory services. Contribute to thought leadership while developing tailored initiatives to protect o...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $115K *

Lead the charge in managing a dynamic team to adjudicate complex workers' compensation claims, ensuring timely resolutions and innovative solutions for diverse clients while fostering a culture of gro...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$143K - $179K *

Analyze customer experiences to drive retention strategies and enhance satisfaction. Collaborate across teams to shape data-driven decisions, develop metrics, and prioritize analytics initiatives that...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.