Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Join a team that's transforming procurement operations through innovative strategies and data-driven solutions. Leverage your consulting expertise to enhance client outcomes and drive impactful change...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Grow your career with a dynamic role that combines technical expertise and sales acumen. Engage with clients, scope security assessments, and collaborate with teams to deliver tailored solutions while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$118K - $197K *

Unlock potential by leading the Third Party Risk Management Program. Drive governance, enhance oversight, and collaborate across teams to ensure effective risk management while mentoring a high-perfor...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$118K - $197K *

Advance your career by leading third-party risk management initiatives, driving program execution, and collaborating across teams to enhance governance and oversight while leveraging data for performa...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$230K - $280K *

Lead a high-performing team to enhance Solutions Consulting, drive cross-functional collaboration and ensure the success of strategic accounts through innovative, accountable deal execution and contin...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Redefine regulatory excellence by leading IND/IDE submissions, ensuring compliance, and collaborating with multidisciplinary teams to advance innovative therapies in a remote setting...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Join a team that's shaping high-impact strategies and narratives for enterprise growth. Collaborate with senior leaders to craft compelling pitches and support organic initiatives, driving success acr...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $105K *

Unlock your potential by leading branch operations, driving strategic initiatives, and enhancing team performance. Collaborate with stakeholders to achieve financial goals while fostering a culture of...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Develop and implement strategic business initiatives to drive growth, expand market presence, and foster partnerships. Lead cross-functional teams to achieve long-term objectives while identifying new...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$70K - $115K *

Join a team that's transforming food safety compliance through innovative SaaS solutions. As a Senior Account Executive, you'll drive sales growth by managing the full sales cycle and building strong...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$89K - $120K *

Transform your career by analyzing and managing commercial real estate financing transactions. Collaborate with clients and stakeholders to assess risks, negotiate terms, and build lasting relationshi...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$238K - $280K *

Shape the future of AI/LLM security by leading innovative offensive strategies, defining technical vision, and driving cross-company initiatives to enhance NodeZero's capabilities in identifying and e...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$132K - $156K *

Unlock potential by leading governance, risk, and compliance initiatives. Collaborate with cross-functional teams to optimize processes, manage projects, and enhance training programs while ensuring e...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Join us to lead the development and execution of clinical study designs, ensuring effective project management and collaboration across teams. Your expertise will drive the success of clinical trials...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$154K - $265K *

Join a team that's redefining sales enablement by leveraging deep expertise in Governance, Risk, and Compliance. Drive impactful solutions that empower sellers to engage effectively with diverse custo...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$106K - $177K *

Lead complex underwriting decisions for high-net-worth and foreign national clients. Collaborate with teams to assess risks, build relationships, and enhance processes while mentoring others in a dyna...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$198K - $327K *

Optimize company operations by leading strategic initiatives, enhancing employee and client experiences, and driving sustainable growth. Collaborate with senior leadership to ensure effective executio...

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$198K - $327K *

Elevate your career by leading operations at a dynamic, employee-owned firm. Drive strategic initiatives, enhance client and employee experiences, and foster sustainable growth while collaborating wit...

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$85K - $130K *

Champion project success by leading complex initiatives, managing scope, budgets, and risks. Collaborate across teams to align execution with business goals, ensuring effective communication and stake...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by providing strategic leadership for a national remote case management team, ensuring service excellence, operational consistency, and client satisfaction while collaborating with...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$93K - $150K *

Drive impactful market research initiatives by leading client relationships, managing complex projects, and mentoring teams. Collaborate with stakeholders to deliver strategic insights that enhance de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $315K *

Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$88K - $105K *

Unlock organizational potential by leading HR strategies that enhance employee engagement, drive performance, and foster a collaborative culture. As a key member of the Senior Leadership team, you'll...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.