Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Grow your career by embracing creativity and innovation in architecture. Collaborate with a passionate team to provide unique solutions that enrich communities and deliver projects showcasing pride an...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$94K - $146K *

Transform cybersecurity by leading comprehensive penetration testing engagements, identifying vulnerabilities, and delivering actionable insights to clients while mentoring junior talent and advancing...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $92K *

Champion virtual behavioral health services by providing evidence-based counseling and developing treatment plans for military personnel, ensuring compliance with clinical standards and enhancing pati...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$134K - $231K *

Shape the future of global supply chain operations by providing strategic legal support, drafting contracts, and ensuring compliance with environmental and safety regulations. Collaborate across funct...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $115K *

Unlock potential by leveraging your pharmacy expertise to drive client growth and retention. Collaborate with teams to provide consultative support and insights in pharmacy and medical policy, enhanci...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $165K *

Elevate your career by driving strategic acquisitions and value creation in a dynamic environment. Collaborate with cross-functional teams to identify targets, lead transactions, and build frameworks...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $125K *

Accelerate progress at our financial reporting function by leading compliance, ensuring accurate statements, and mentoring a skilled team. Drive technical accounting excellence and support executive d...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $110K *

Lead financial management and analysis efforts to support strategic planning and budget execution for DHS initiatives, ensuring alignment with mission priorities and stakeholder requirements while dri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Champion the management of complex liability claims, ensuring thorough investigations, negotiations, and settlements. Collaborate with internal and external stakeholders to maintain high standards of...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$144K - $210K *

Drive compliance excellence by leading a team focused on identifying and addressing control gaps and violations across financial services, ensuring adherence to regulatory standards while enhancing su...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$89K - $119K *

Join the charge in managing complex litigated claims, guiding strategy, and negotiating settlements. Leverage your expertise to achieve timely resolutions while balancing costs and exposure in a dynam...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$71K - $114K *

Elevate your legal career by providing essential support to judicial officers. Conduct in-depth research, draft legal documents, and assist in case management to ensure efficient court operations acro...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$113K - $188K *

Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $236K *

Reimagine your career by leading a dynamic team in financial advisory. Drive impactful projects with finance executives, enhance reporting processes, and foster client relationships while developing j...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $180K *

Join a pioneering team to build an AI-enabled care delivery platform, bridging clinical expertise and engineering to create safe, effective patient care solutions. Drive innovation from concept to pro...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$237K - $275K *

Join a team that's redefining client partnerships by owning strategic accounts, driving revenue growth, and ensuring client satisfaction through integrated solutions and executive relationships across...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Media

$120K - $160K *

Drive the advancement of high-value, complex deals, partnering with C-Suite executives to create innovative solutions that expand the organization's portfolio and enhance strategic account growth...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $160K *

Unlock potential by leading complex cyber investigations, mentoring junior analysts, and analyzing sophisticated threats to safeguard AI systems from misuse. Drive impactful decisions and enhance safe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$186K - $278K *

Lead strategic initiatives in healthcare economics, collaborating with national accounts to enhance patient outcomes and drive market access. Foster relationships with key stakeholders while executing...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by providing expert XBRL project support, ensuring compliance and accuracy in financial reporting for diverse clients while collaborating across teams to enhance project delivery and...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$115K - $135K *

Help us expand our commercial lending portfolio by building client relationships and delivering tailored financing solutions. You'll play a key role in driving business growth while ensuring an except...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.