Senior Clinical Trial Manager Jobs

Explore senior clinical trial manager jobs with Ladders, where you can find vetted professional opportunities paying $100,000 or more. Senior Clinical Trial Managers guide clinical studies from planning through closeout, helping ensure trials are conducted ethically, efficiently, and in compliance with applicable regulations and protocols.

What Senior Clinical Trial Managers Do

These leaders oversee trial operations, timelines, budgets, vendors, and study teams. Responsibilities may include coordinating site activation and enrollment, monitoring study progress, managing risks and deviations, reviewing documentation, and communicating updates to sponsors, investigators, and internal stakeholders. The scope of a role varies by employer, therapeutic area, and development phase.

Skills and Experience Employers Seek

Employers commonly look for substantial clinical research experience, strong project and people-management skills, and familiarity with Good Clinical Practice (GCP), clinical trial regulations, and quality systems. Success also depends on clear communication, sound judgment, attention to detail, and the ability to resolve issues across a complex, cross-functional environment. Some positions favor experience with particular therapeutic areas, global studies, or clinical operations platforms.

Career Paths and Opportunities

Senior Clinical Trial Managers work for pharmaceutical and biotechnology companies, contract research organizations (CROs), and other clinical research organizations. Depending on experience and organizational structure, this role can lead to director-level positions in clinical operations or broader clinical development leadership. Browse current opportunities to compare responsibilities, qualifications, work arrangements, and compensation.

Find Senior Clinical Trial Manager Jobs on Ladders

Use Ladders to discover vetted senior clinical trial manager openings with salaries of $100,000 or more. Review each listing for its location, compensation details, required experience, and study responsibilities to find opportunities aligned with your expertise and career goals.

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$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive excellence in clinical research by overseeing site management, ensuring compliance, and fostering collaboration among stakeholders to achieve study milestones efficiently and effectively...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Lead the charge in clinical research by ensuring study compliance and performance at assigned sites. Collaborate with cross-functional teams to drive timely delivery of study milestones while maintain...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Grow your career with a dynamic role overseeing clinical studies, ensuring compliance and performance at assigned sites. Collaborate with cross-functional teams to drive successful study delivery and...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Lead clinical trial monitoring efforts, ensuring compliance with protocols and regulations. Collaborate with teams to enhance data integrity and site performance while providing training and support t...

Burlington, ONIn-Person

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $138K *

Join a team that's dedicated to delivering high-quality clinical trial outcomes while ensuring compliance and patient safety. Collaborate with stakeholders and investigators to drive efficient study m...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $138K *

Champion clinical trial excellence by overseeing monitoring activities, ensuring compliance with protocols and regulations, and fostering collaboration across teams to drive successful trial execution...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion clinical trial excellence by overseeing monitoring activities, ensuring compliance with protocols and regulations, and fostering collaboration across teams to drive successful outcomes and co...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead clinical trial monitoring efforts, ensuring compliance with protocols and regulations while fostering collaboration across teams to enhance data integrity and site performance...

Blue Bell, PARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to advancing clinical research by monitoring trials, ensuring compliance with protocols and regulations, and contributing to the success of innovative healthcare solutions...

Montreal, QCIn-Person

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $135K *

Lead the charge in clinical research by monitoring trials, ensuring compliance with protocols and regulations, and enhancing patient safety. Collaborate with teams to drive successful outcomes in drug...

Montreal, QCIn-Person

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $135K *

Elevate your career by ensuring clinical trials meet regulatory standards and protocols. As a key player, you'll monitor studies, collaborate with teams, and contribute to life-saving research in a dy...

Burlington, ONIn-Person

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join us to lead clinical trial monitoring, ensuring adherence to protocols and regulatory standards while fostering collaboration and quality improvement across multiple sites in the oncology field...

Burlington, ONRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Advance your career by serving as the primary liaison between investigational sites and sponsors, ensuring compliance and supporting site operations across multiple therapeutic areas in a dynamic clin...

Florida, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive your career in pharmacovigilance by leading cross-functional teams, ensuring compliance with global regulations, and enhancing safety data processes. Mentor others while contributing to strategi...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$157K - $168K *

Lead all phases of clinical trials with autonomy and support, managing teams and vendors to ensure successful execution, budgeting, and compliance while fostering strong collaborations with stakeholde...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $115K *

Transform cancer therapy development by leading pharmacovigilance efforts. Collaborate with cross-functional teams to ensure regulatory compliance and manage serious adverse events, contributing to in...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $115K *

Explore a pivotal role in pharmacovigilance, ensuring regulatory compliance and safety management for cancer therapies. Collaborate with cross-functional teams to enhance drug safety processes and sup...

Princeton, NJRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead and coordinate clinical project activities, ensuring timely delivery, budget adherence, and quality standards. Engage stakeholders, manage risks, and develop team capabilities in a dynamic enviro...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $150K *

Shape your career by managing clinical research studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficiently and effectively...

Boston, MARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $125K *

Join a dynamic team as a Senior Clinical Trial Associate, supporting clinical studies and operations. Contribute to trial execution, manage documentation, and enhance processes while developing your c...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a team focused on excellence in clinical trial management, overseeing site interactions, ensuring data integrity, and driving compliance. You'll lead efforts in patient safety, recruitment, and d...

Massachusetts, USRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Lead the charge in overseeing clinical trial management, ensuring compliance, data integrity, and patient safety. Collaborate with cross-functional teams to meet project milestones and manage risks ef...

New Jersey, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Unlock potential by leading clinical trial initiatives, ensuring adherence to safety, compliance, and quality standards. Collaborate with cross-functional teams to manage all phases of clinical resear...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to ensuring the success of clinical trials through effective site management, compliance oversight, and risk mitigation strategies, all while fostering collaboration acros...

Wyoming, USRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Senior Clinical Trial Manager do?question toggle

    A Senior Clinical Trial Manager leads the operational delivery of clinical studies, coordinating timelines, budgets, sites, vendors, and cross-functional teams while helping maintain protocol, quality, and regulatory compliance.

  • What qualifications are typically required for Senior Clinical Trial Manager jobs?question toggle

    Requirements vary, but employers often seek significant clinical research or clinical operations experience, experience managing studies or teams, and knowledge of GCP and applicable clinical trial regulations. Some roles require therapeutic-area or global-trial expertise.

  • Where do Senior Clinical Trial Managers work?question toggle

    They may work for pharmaceutical and biotechnology companies, CROs, and other organizations involved in clinical research. Roles can support studies across a range of therapeutic areas and development phases.

  • How much do Senior Clinical Trial Managers earn?question toggle

    Compensation varies based on employer, location, experience, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check individual listings for salary and compensation details.

  • How can I find Senior Clinical Trial Manager jobs paying $100,000 or more?question toggle

    Browse Senior Clinical Trial Manager listings on Ladders and review each posting’s salary information, qualifications, location, and responsibilities to identify opportunities that fit your background.