Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist Algorithm Lead
$151K - $261K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
5 days ago
Senior Principal Scientist, Drug Substance
$175K - $230K *
Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...
1 week ago
Senior Principal, AI Product Owner - Agentic AI
$175K - $230K *
Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...
4 days ago
Senior Principal, AI Product Owner - LLMs
$175K - $230K *
Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...
4 days ago
Director, Scientific Solutions
$130K - $180K *
Join us as a key leader in driving the commercial strategy for scientific solutions while developing a high-performance team that engages top-tier clients in the life sciences sector. Own flagship acc...
Today
$125K - $224K *
Contribute to groundbreaking research by enhancing atmospheric radiative transfer models, collaborating with a team of experts, and driving innovation in numerical methods within the scientific commun...
1 week ago
Scientific Product Solutions Lead
$100K - $130K *
Innovate in the development of AI-powered scientific solutions, collaborating with cross-functional teams to design, configure, and implement systems that enhance scientific workflows and data managem...
Today
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
$171K - $214K *
Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...
1 week ago
Senior Principal, AI Product Owner - Machine Learning
$175K - $230K *
Drive your career with innovative AI and machine learning products that enhance global supply chain efficiency. Own strategy, elevate data standards, lead governance, and foster collaboration in a sen...
2 days ago
$120K - $150K *
Transform the future of drug development by leading innovative simulation projects, acting as a scientific liaison between clients and teams, and driving advances in pharmacometrics with your expertis...
2 days ago
$100K - $130K *
Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...
2 weeks ago
Senior Clinical Scientist, ECD
$142K - $178K *
Lead the charge in clinical development for early cancer detection by driving study execution, data review, and strategic insight. Collaborate with cross-functional teams to enhance clinical strategy...
Yesterday
$120K - $135K *
Advance your career by leading complex AI and IT projects. This high-visibility role entails managing cross-functional teams and driving accountability across multiple workstreams, ensuring successful...
1 week ago
Staff Scientist, Imaging Systems
$234K - $271K *
Lead the charge in developing cutting-edge AI and image processing solutions for cardiac imaging, translating clinical needs into innovative algorithms while collaborating across functions to enhance...
6 days ago
Director, PF Project Delivery - Project Farma
$150K - $170K *
Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...
Reposted 2 weeks ago
$165K - $206K *
Lead the charge in transforming complex data into actionable insights, partnering with stakeholders to measure and optimize commercial strategies, and architecting large datasets to influence critical...
4 weeks ago
Senior Principal Architect, AI
$173K - $277K *
Innovate within the AI Center of Excellence to architect and govern advanced AI solutions, shaping how AI is designed, deployed, and scaled across all engineering projects with a commitment to excelle...
5 days ago
$152K - $190K *
Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...
Reposted 1 week ago
Senior Director of Program Management, Global Operations
$150K - $180K *
Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...
Reposted 3 weeks ago
Research Scientist, Virtual Cell Modelling & Perturbative Biology Foundation Models
$120K - $150K *
Join us to drive innovations in drug discovery through advanced ML techniques, focusing on predictive modeling in cellular responses. Collaborate with a diverse team to turn complex data into actionab...
Today
Senior Research Scientist, Evidence Synthesis
$90K - $120K *
Lead innovative projects in evidence synthesis as a Senior Research Scientist, collaborating across multiple teams to develop client-ready deliverables and oversee systematic reviews while mentoring j...
Today
$90K - $120K *
Advance pharmaceutical marketing analytics by leading insight delivery and measurement strategies. Oversee KPI frameworks, reporting processes, and data visualization to ensure compelling insights tha...
5 days ago
$100K - $130K *
Join a team that's leading innovative Cost Improvement Projects in medical devices. You'll manage engineering efforts, ensuring compliance while driving change and collaboration across cross-functiona...
3 weeks ago
$130K - $180K *
Join a dynamic team to lead product strategy connecting tech investments to business outcomes, enhancing operational success, and driving innovation while fostering collaboration and developing high-p...
Yesterday
$66K - $99K *
Shape the future of environmental projects by leading assessments, remediation, and team management. Drive successful project delivery while mentoring talent and maintaining client relationships throu...
Today
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.