Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Regulatory Affairs Director *PC 954
$201K - $237K *
Shape regulatory strategies for CMC in cell therapy programs and collaborate across teams to ensure compliance with health authority requirements, supporting trials and product approvals throughout th...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Unlock potential by leading CMC regulatory strategies for cell therapies. Collaborate across teams to ensure compliance, prepare submissions, and drive product lifecycle success, while engaging with g...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Architect innovative regulatory strategies for CMC in cell therapy, guiding teams and leading submissions throughout product development, ensuring compliance and successful health authority interactio...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Champion regulatory CMC strategies to elevate cell and gene therapies. Drive cross-functional collaborations, oversee global submissions, and ensure compliance. Lead efforts to mitigate risks and supp...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Empower progress at the intersection of regulatory compliance and cell therapy. Lead CMC strategies for global submission readiness, partnering with cross-functional teams to navigate approvals, and e...
Yesterday
Principal Data Scientist (64_2026.3)
$200K - $215K *
Contribute to transforming consumer spend data into predictive intelligence, leading a talented team across predictive modeling and campaign measurement while ensuring standards, privacy, and methodol...
2 weeks ago
$110K - $140K *
Contribute to a seamless customer experience by connecting clients with technical and scientific operations, guiding them from initial inquiries to successful project completion in a dynamic biotechno...
3 weeks ago
Chief of Staff, Enterprise AI & Data Science
$137K - $185K *
Join us in a strategic leadership role driving operations, cross-functional alignment, and organizational effectiveness across AI & Data Science initiatives in a fast-paced environment. Make a profoun...
2 weeks ago
Research Scientist: Post-Training
$120K - $145K *
Unlock potential by training large models into production-ready robotic systems. Engage in fine-tuning, performance evaluation, and real-world implementations while becoming a full-stack ML roboticist...
1 week ago
$145K - $179K *
Optimize cancer diagnostics through innovative statistical and data science methods, ensuring valid study designs and timely delivery of high-quality analyses and regulatory documents in collaboration...
3 weeks ago
$204K - $306K *
Lead the charge in integrating AI with scientific workflows, mentoring engineers, and delivering innovative applications that enhance research collaboration. Drive technical strategy and foster a high...
2 weeks ago
$204K - $306K *
Champion groundbreaking solutions by leading engineers who integrate AI with scientific workflows, driving innovation for life-changing breakthroughs in research while fostering a collaborative enviro...
2 weeks ago
$90K - $100K *
Empower production excellence by leading operational activities, ensuring compliance with safety and quality standards while managing resources efficiently. Coach and mentor teams, drive continuous im...
Yesterday
Principal Machine Learning Engineer
$126K - $264K *
Elevate the future of machine learning by implementing production-ready models, automating workflows, and ensuring model performance. Collaborate with diverse teams to integrate solutions and troubles...
6 days ago
Principal Process Engineer, Advanced Manufacturing Technical Lead
$128K - $193K *
Join our team to provide technical leadership across engineering initiatives, drive process improvements, mentor diverse teams, and enhance manufacturing capabilities for life-saving medical technolog...
1 week ago
$120K - $151K *
Champion innovation in laboratory automation by driving the development, troubleshooting, and validation of cutting-edge platforms for the NGS diagnostics arena, empowering precise and efficient workf...
6 days ago
Computational Scientist, Quantum Energy Systems
$120K - $145K *
Accelerate progress at a cutting-edge startup by simulating materials at atomic scales. Collaborate closely with experimental teams to drive fast, data-driven decisions that reshape innovation in quan...
3 weeks ago
$90K - $130K *
Unlock potential by managing diverse environmental projects, overseeing teams and budgets, ensuring compliance with regulations, and fostering client relationships for impactful remediation and redeve...
Reposted 3 days ago
$110K - $130K *
Drive the success of product portfolios from conception to commercialization, ensuring competitiveness and growth through strategic customer engagement and data-driven decision-making. Collaborate cro...
4 days ago
$110K - $130K *
Join us to drive the success of our product portfolio from conception to commercialization, ensuring growth and competitiveness through strategic customer engagement and continuous improvement. Lead c...
4 days ago
$100K - $120K *
Lead the charge in complex NPI and strategic improvement projects, ensuring cross-functional collaboration, adherence to timelines, and business alignment while mentoring project managers to enhance e...
2 weeks ago
Sr Director, Commercial Excellence
$210K - $250K *
Drive global sales enablement, enhancing productivity and revenue growth. Lead AI transformation, analytics, and cross-functional collaboration to optimize sales strategies, training, and processes fo...
Yesterday
Sr Director, Commercial Excellence
$210K - $250K *
Empower global sales enablement and drive strategic transformations. Lead training, support, and AI integration to enhance sales productivity and optimize commercial operations across diverse teams an...
Yesterday
Sr Director, Commercial Excellence
$210K - $250K *
Champion global sales enablement and drive AI transformation to enhance the effectiveness of commercial operations while developing strategies to boost revenue and productivity across multiple regions...
Yesterday
Sr Director, Commercial Excellence
$210K - $250K *
Join a dynamic team to elevate global sales productivity through innovative strategies, analytics, and AI transformation. Lead training and enablement initiatives to empower sales staff and improve cu...
Yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.