Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$108K - $170K *

Transform elemental measurements into reliable, machine-readable data while collaborating with AI and software teams to enhance materials characterization and accelerate discovery in this hybrid role...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Elevate the way models learn by measuring and enhancing data quality in collaboration with leading researchers, driving innovation in a dynamic team environment...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$99K - $198K *

Shape the future of cancer diagnostics as a Sr. Scientist, driving innovative R&D projects and mentoring junior scientists. Lead experiments, analyze complex data, and collaborate to optimize NGS solu...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $198K *

Innovate in cancer diagnostics by leading complex research projects, mentoring junior scientists, and optimizing next-generation sequencing workflows to enhance clinical testing quality and performanc...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $121K *

Innovate within a collaborative team to optimize ligands using molecular biology and discovery technologies, supporting projects from research to commercialization in a dynamic environment...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Optimize process development and scaling for active pharmaceutical ingredients. Conduct independent research, manage experiments, and ensure compliance with safety and quality standards while collabor...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$67K - $101K *

Unlock potential by driving innovation in lab experiments focused on biomarker measurements. Contribute to research and development initiatives while ensuring data integrity and supporting lab functio...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$124K - $230K *

Champion cutting-edge research and drive the pharmacological evaluation of innovative drug candidates while collaborating within multidisciplinary teams to enhance therapeutic capabilities and patient...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $180K *

Shape the future of scientific exploration by leading innovative research initiatives, applying advanced methodologies, and mentoring emerging scientists to solve complex technical challenges...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Transform the future of material innovation! Collaborate across R&D, production, and quality control to enhance product development and analytical testing through state-of-the-art instrumentation and...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$214K - $337K *

Shape the future of mass spectrometry and pharmacology through scientific leadership, guiding assay development, and fostering collaboration to drive impactful drug discovery across multidisciplinary...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$132K - $188K *

Drive groundbreaking pharmacology research by leading in vivo studies, establishing PK/PD relationships, and collaborating with cross-functional teams to advance oncology drug development efforts...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $119K *

Join a team that's pushing the boundaries of material science through advanced electron microscopy. Contribute to groundbreaking research by analyzing complex materials, collaborating with experts, an...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Support innovative research by conducting advanced solid-state characterization and developing strategies for solid form screening of complex bRo5 molecules. Collaborate within multidisciplinary teams...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Partner with us to lead a Senior Chemist role in a dynamic lab environment, ensuring safety and compliance while mastering chemical characterization and equipment validation. Leverage your expertise t...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive clinical trial strategies across US & EU, collaborating with diverse teams to ensure regulatory success and product advancement. Leverage your expertise to mentor others and stay at the forefron...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate your career by driving innovative process solutions that enhance manufacturing efficiency and sustainability. Collaborate with a dynamic team to translate scientific discoveries into impactful...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Join a dynamic team driving viral-entry biology initiatives towards therapeutic advancements. Lead research, develop assays, and collaborate across functions to optimize gene delivery and enhance scie...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join our team and lead in environmental consulting as you mentor staff, manage key projects, and develop client relationships while ensuring regulatory compliance and quality outcomes for business gro...

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$131K - $206K *

Develop innovative drug candidates and expand knowledge through collaboration with multidisciplinary teams by employing expert synthetic chemistry and data analysis to streamline target identification...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $283K *

Lead a high-performing team in developing innovative biomarker assays that drive drug discovery and clinical strategies, collaborating with cross-functional partners to enhance patient-focused researc...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in overseeing geological operations for a high-tonnage open-pit mining project. Ensure efficient ore control, geometallurgical strategies, and data management, driving collaboration ac...

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$116K - $175K *

Innovate within R&D to develop and commercialize new VMS products. Collaborate across teams, lead improvement projects, and mentor junior staff while driving product quality and compliance in a dynami...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$93K - $156K *

Transform pharmaceutical development by designing scalable synthetic processes. Collaborate with multi-disciplinary teams to innovate and apply synthetic methodologies for diverse drug candidates in a...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $156K *

Join the Cardiovascular Discovery Biology team to drive drug discovery by identifying and validating therapeutic targets and biomarkers, collaborating across disciplines, and mentoring junior scientis...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.