Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$90K - $130K *

Lead the charge in analyzing complex omics data to drive actionable insights that positively impact patient care and treatment decisions, while collaborating closely with scientific teams for innovati...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Join a team that's dedicated to enhancing client experiences by managing complex survey projects and delivering tailored solutions. Drive relationship-building and ensure client satisfaction as you ta...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $130K *

Unlock insights from complex patient omics data using advanced analytical techniques. Lead impactful projects within a dynamic team, fostering collaboration and innovation to drive patient-centered so...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $280K *

Drive innovative solutions as a Principal Cloud Systems Engineer. Bridge research and practical applications in cloud-native architectures, leading a team focused on optimizing edge networks and autom...

3 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$185K - $260K *

Unlock potential by driving architectural strategy and engineering excellence in bioinformatics systems. Collaborate across teams to lead complex projects, ensuring high-quality software development a...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K *

Deliver impactful data solutions by leading analytics projects, creating data pipelines, and developing AI/ML applications. Collaborate with stakeholders to provide strategic insights and optimize bus...

Today

  •   Less than 5 years exp.  •   Business Services

$90K - $120K *

Accelerate progress at a large-scale facility relocation project, managing end-to-end operations from planning to execution. Enhance efficiency through strategic scheduling and stakeholder collaborati...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$74K - $118K *

Join the Protein Design team to advance vaccine development by utilizing cutting-edge techniques in protein expression, purification, and characterization within a collaborative research environment f...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$218K - $295K *

Unlock your potential by leading innovations in generative AI and Agentic AI. Collaborate with engineering teams to build scalable solutions, enhancing enterprise productivity through intelligent agen...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Champion the planning and execution of cybersecurity initiatives, managing cross-functional teams to enhance capabilities in Defensive Cyber Operations for Space, ensuring alignment with strategic goa...

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$117K - $128K *

Champion the development and optimization of oligonucleotide production processes, ensuring technology transfer from R&D to manufacturing, driving efficiency, and enhancing quality performance across...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Strategize operational excellence and EHS leadership to enhance safety, compliance, and infrastructure reliability. Lead diverse teams while driving capital planning, engineering projects, and sustain...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Shape the future of innovative products by designing, developing, and testing cutting-edge technologies alongside cross-functional teams to drive quality solutions from ideation to commercialization...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $165K *

Transform the future of biosensors by leading design efforts in protein engineering, guiding lab screenings, and mentoring junior scientists. Collaborate with teams to optimize performance and integra...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$144K - $227K *

Lead innovative data science efforts in Neuroscience biomarker discovery, integrating biofluid proteomics and diverse omics data. Collaborate with multidisciplinary teams to drive precision medicine s...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$86K - $112K *

Empower scientific innovation by engaging in therapeutic candidate development and evaluation, utilizing advanced assay systems. Contribute to preclinical research efforts addressing viral and bacteri...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead and enhance Quality Management Systems for North America operations, ensuring compliance with industry standards while driving continuous improvement and operational excellence through strategic...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Champion excellence by leading corporate Quality Management Systems across North America. Drive compliance and improvement initiatives, collaborating with cross-functional teams to enhance quality sta...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $130K *

Lead transformative engineering initiatives, driving projects to success by managing cross-functional teams and delivering innovative hardware solutions on schedule and within budget. Collaborate clos...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$92K - $132K *

Engage in innovative assay development as a Research Scientist, leading complex projects, analyzing data, and delivering actionable insights. Collaborate with cross-functional teams to advance scienti...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $145K *

Collaborate with multidisciplinary teams to design and execute high-throughput screening workflows, generating robust datasets to propel drug discovery efforts and optimize experimental designs across...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Join a dynamic team to lead labor relations strategies, oversee negotiations, and enhance compliance. Play a pivotal role in managing labor campaigns and analytics, while fostering effective partnersh...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$185K - $200K *

Reimagine the future of bioanalytical services by leading the launch and growth of a U.S. lab. Drive strategic business initiatives, optimize operational excellence, and foster a high-performance cult...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Accelerate protein design innovation by leading computational campaigns, collaborating with top scientists, and integrating AI methods to enhance the design-build-test cycle for cutting-edge therapeut...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $115K *

Elevate your career by driving peptide and oligonucleotide processes from lab to manufacturing. You'll collaborate with cross-functional teams to optimize and scale processes for high-quality API deve...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.