Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Sr Technical Program Manager - Advanced Opto-Electronics
$200K - $280K *
Join us to lead cutting-edge optoelectronic development programs. Oversee multi-disciplinary teams, manage risk, and drive project execution from inception to manufacturing for innovative products in...
2 weeks ago
Senior Principal Agentic Engineer
$129K - $231K *
Accelerate progress at the forefront of cloud-native automation, where you will architect and enhance an agentic resolution platform, significantly impacting operational efficiency and developer exper...
Yesterday
Senior Research Associate, Biosensor Assay Development
$80K - $95K *
Develop and optimize cutting-edge biosensor assays through innovative experimental design, supporting laboratory operations and product development to ensure high-quality diagnostics and research appl...
4 days ago
$150K - $180K *
Elevate the future of AI by leading the design and deployment of transformative systems that drive enterprise innovation. Collaborate cross-functionally to enhance software engineering practices and s...
1 week ago
$254K - $381K *
Lead the charge in architecting scalable AI solutions that drive enterprise innovation and modernization through effective collaboration, while establishing governance frameworks and best practices ac...
Reposted 4 weeks ago
$254K - $381K *
Bring your expertise to lead the design and modernization of enterprise workflows. Drive innovation through AI solutions and collaborate with cross-functional teams to enhance user experience and deli...
Reposted 4 days ago
$150K - $180K *
Discover and drive enterprise application architecture standards, enhancing interoperability across Lines of Business. Lead AI-driven modernization efforts and promote innovative practices to elevate...
6 days ago
$150K - $180K *
Empower your career by driving enterprise application architecture and AI modernization. Lead cross-functional teams, define technical standards, and influence strategic initiatives to enhance system...
6 days ago
$150K - $180K *
Shape the future of AI by architecting large-scale solutions that drive enterprise-wide innovation. Collaborate with engineering teams to implement modernized practices and establish governance framew...
1 week ago
$150K - $180K *
Drive the design and deployment of large-scale AI systems, influencing enterprise innovation. Lead modernization efforts, establish technical standards, and provide mentorship in a collaborative hybri...
1 week ago
Senior Engineer, Customer Quality Engineering
$110K - $120K *
Join a dynamic team as a Customer Quality Engineer, where you'll collaborate across functions to enhance quality and customer satisfaction in the semiconductor industry through effective problem-solvi...
6 days ago
Senior Engineer, Customer Quality Engineering
$100K - $120K *
Lead the charge in enhancing customer quality through cross-functional engagement, project management, and strategic problem-solving within a dynamic, high-visibility environment. Drive initiatives th...
3 weeks ago
Senior Engineer, Customer Quality Engineering
$100K - $120K *
Join a dynamic team as a Customer Quality Engineer, engaging cross-functionally to enhance success with customers through problem-solving, project development, and effective communication in a high-im...
3 weeks ago
Senior Study Lead, Biopharmaceuticals (GMP)
$100K - $120K *
Lead the charge in managing complex routine projects within a GMP laboratory, ensuring compliance and high-quality outputs. Collaborate with teams to drive continuous improvement, mentor staff, and al...
5 days ago
Senior Manager of Validation Engineering
$110K - $130K *
Lead the Validation team in implementing critical qualification procedures for sterile injectables. Collaborate with various stakeholders to ensure compliance and optimal performance in manufacturing...
3 weeks ago
Preclinical Principal Scientist, Research & Development
$130K - $210K *
Elevate preclinical research initiatives by leading study design and execution. Collaborate across teams to ensure compliance and strategy alignment, guiding medical device projects from conception to...
2 weeks ago
Program Manager / Senior Program Manager, Life Science
$110K - $149K *
Drive innovative project management across diverse teams, ensuring timely and budget-compliant delivery of client-centric solutions in life sciences. Foster collaboration and leadership while managing...
6 days ago
$110K - $130K *
Lead the future of process engineering by managing multidisciplinary teams, ensuring project deliverables meet industry standards, and mentoring junior engineers for complex technical challenges on va...
Today
$156K - $229K *
Elevate your career by leading process engineering initiatives and managing multidisciplinary teams. Leverage your expertise to deliver quality solutions on time and within budget while mentoring juni...
1 week ago
Senior Scientist, siRNA Design and Off-Target Analysis
$120K - $145K *
Optimize siRNA design and off-target assessment by integrating genomic data and machine learning. Collaborate with cross-functional teams to advance RNA-based therapeutics, ensuring safer and more sel...
4 weeks ago
Labeling and Packaging Scientist - Advanced Therapies Manufacturing
$67K - $173K *
Unlock potential by leading technical oversight for labeling and packaging processes in a cutting-edge genetic medicine facility. Play a vital role in startup, validation, and continuous improvement o...
Today
Scientist II, Silicon Photonics
$128K - $170K *
Drive innovative measurement and analysis for electro-optic materials and devices, enhancing data quality across full characterization from thin films to final device testing, while collaborating with...
Today
$80K - $95K *
Shape the future of chemical engineering by enhancing operational excellence and driving process improvements in a state-of-the-art facility. Collaborate with teams to monitor performance and execute...
Reposted 2 weeks ago
Engineer I, Instrument Support
$105K - $130K *
Engineer innovative solutions by supporting and enhancing ARGO systems. Deliver hands-on troubleshooting, maintenance, and continuous improvements in collaboration with cross-functional teams, ensurin...
2 weeks ago
$79K - $125K *
Engage in a dynamic role that links advanced software solutions with customer needs, delivering tailored support and collaborating with R&D teams to optimize software applications for semiconductor ma...
Reposted yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.