Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Senior Scientist & Program Manager, Neuroscience
$120K - $140K *
Champion scientific initiatives by managing projects and workshops, while validating innovative antibody applications in neuroscience. Collaborate with external partners and internal teams to ensure i...
4 days ago
Scientist - Screening & Analytical Chemistry
$90K - $120K *
Engineer high-throughput analytical workflows and lead method development for metabolite quantification. Collaborate with multidisciplinary teams while demonstrating creativity and initiative to enhan...
2 weeks ago
Principal Scientist - Formulation
$135K - $165K *
Transform early-stage research into innovative solutions by exploring novel materials and chemistries. Drive projects from concept to prototype, shaping strategies and ensuring seamless collaboration...
1 week ago
Principal Scientist, Nonclinical Safety Lead
$130K - $180K *
Discover innovative solutions as a Principal Scientist in Nonclinical Safety, leading toxicology efforts for diverse therapeutic projects. Collaborate with multidisciplinary teams to drive drug candid...
Reposted 2 weeks ago
Principal Scientist, Nonclinical Safety Lead
$130K - $180K *
Pioneer innovative nonclinical safety strategies in a collaborative role within diverse project teams. Provide toxicology leadership for drug candidates across multiple therapeutic areas, enabling saf...
Reposted 2 weeks ago
Sr. Scientist, Biomarker Discovery
$123K - $164K *
Shape the future of immunology therapeutics by leading biomarker discovery research. Execute innovative studies, analyze data, and communicate insights to drive clinical strategies and influence cross...
5 days ago
Principal Research Scientist I
$120K - $150K *
Lead the charge in advancing innovative injection devices from concept to market, collaborating across teams to ensure successful product development, regulatory submission, and industrialization whil...
1 week ago
Principal Scientist, Biomarker Data Sciences
$141K - $188K *
Join a pioneering team as you lead multi-omics analysis from clinical trials, translating complex data into vital biological insights. Collaborate with cross-functional experts to advance clinical str...
1 week ago
$120K - $150K *
Lead and innovate with a dynamic R&D team to develop cutting-edge alloys, combining experimental metallurgy and computational techniques. Mentor emerging talent while driving projects from concept to...
2 weeks ago
Senior Scientist, Process Chemistry
$175K - $200K *
Join a team that designs and executes innovative multi-step experimental studies, ensuring scalable processes through strong collaboration and technical expertise in process development and analytical...
2 days ago
Principal Scientist, Purification Process Development
$159K - $207K *
Unlock your potential by leading purification process characterization and validation, authoring IND/BLA sections, and driving late-stage activities to support our large molecule pipeline. Join a dyna...
1 week ago
Senior Scientist, Drug Product Manufacturing and Development
$143K - $175K *
Drive progress in drug product formulation and manufacturing by collaborating with partners and ensuring successful development through clinical and commercial stages. Leverage your expertise to optim...
1 week ago
Principal Applied Scientist, Sponsored Products and Brands
$228K - $309K *
Elevate brand advertising through innovative Gen AI solutions, driving product strategy and design across teams while collaborating on cutting-edge technologies to enhance user experiences and exceed...
1 month ago
Senior/Principal Scientist, Formulation Development
$115K - $170K *
Unlock potential by leading formulation development for oral solid dosage programs. Drive innovation, mentor junior scientists, and serve as a technical expert in a dynamic CDMO environment, supportin...
5 days ago
$117K - $184K *
Lead the strategic commercialization of late-stage biologics by delivering effective cell culture processes. Oversee technical execution, mentor junior scientists, and foster cross-functional teamwork...
1 week ago
Principal Scientist, QC Compliance
$113K - $177K *
Unlock potential by leading compliance strategies in Quality Control, ensuring laboratory operations meet regulatory standards while driving efficiency, continuous improvement, and cross-functional co...
4 days ago
$80K - $100K *
Join a team that's driving innovative pharmaceutical formulation development. Leverage your expertise in laboratory practices and scientific principles to create and deliver safe, effective drug produ...
1 week ago
Principal Scientist, Medical Device Expert, L'Oreal Research & Innovation
$126K - $184K *
Champion regulatory excellence as a Principal Scientist, leading medical device strategy & compliance for impactful projects across the Americas, collaborating with global teams & ensuring the success...
Reposted 2 weeks ago
Research Specialist / Sr Scientist, Assay Sciences, Discovery Pharmacology
$129K - $225K *
Advance your career with this pivotal role in drug discovery, focusing on the development and execution of cell-based and biochemical assays to drive innovation in aging biology and therapeutic soluti...
Today
Principal Scientist, Small Molecule
$100K - $130K *
Lead technical projects and laboratory operations, providing expertise in complex analytical applications while driving innovation and enhancing productivity for client programs in a GMP environment...
3 days ago
Sr. Scientist, Analytical Development
$120K - $150K *
Pioneer innovative analytical methods in our lab, ensuring adherence to cGMP standards while leading a skilled team. Drive the development and validation of assays for biologics, facilitating tech tra...
3 weeks ago
Senior Principal, Scientist, Computational Sa
$140K - $222K *
Join a cutting-edge team to pioneer in silico safety assessments using advanced multi-omics data and AI techniques, enhancing drug discovery by providing actionable insights and facilitating risk-base...
3 weeks ago
$120K - $150K *
Champion the advancement of plasma diagnostics for fusion generators, leading design and analysis to optimize performance. Collaborate across teams to drive innovation and best practices, contributing...
5 days ago
$105K - $130K *
Champion innovation in materials science, leading cross-functional teams to enhance product performance and consumer experience while focusing on strategic development and execution of projects across...
Reposted yesterday
Senior Scientist, Analytical Chemistry
$150K - $180K *
Advance analytical strategies and methodologies in GC-MS for fragrance discovery. Collaborate across teams enforcing scientific rigor while mentoring junior scientists, all within a dynamic and autono...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.