Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$80K - $109K *
Explore a role that encourages curiosity and growth by leading impactful ADME projects, collaborating with experts, and driving innovative research methodologies in a dynamic team environment...
1 week ago
Research & Technology Innovation Scientist
$80K - $100K *
Champion innovation by driving scientific research, product development, and cross-functional coordination to enhance early-stage evaluation and project management efforts in tissue regeneration and a...
2 weeks ago
Principal Scientist / Associate Director, Agentic AI Research for Materials Science
$288K - $420K *
Reimagine the future of materials science by leading a team in developing agentic AI systems. Own the scientific rigor and technical direction to drive innovations from research to production, ultimat...
2 weeks ago
Principal Scientist / Associate Director, Agentic AI Research for Materials Science
$288K - $420K *
Lead the charge in developing agentic AI systems for materials science, setting technical direction, mentoring a team, and integrating cutting-edge research with practical applications. Drive innovati...
2 weeks ago
Senior Managing Regulatory Scientist
$174K - $213K *
Champion regulatory excellence in food safety and nutrition, leveraging deep expertise to guide clients through complex compliance challenges and develop impactful strategies for product approvals and...
Reposted 5 days ago
Principal Scientist, Analytical Development
$170K - $185K *
Unlock your potential by leading the cell potency analytical development team. Drive strategic initiatives to develop and optimize assays for NK cell therapies while mentoring a talented group of scie...
1 week ago
Senior Scientist, Biologics Formulation
$140K - $180K *
Join a team that's pioneering high-concentration biologics formulation. Lead innovative strategies, mentor talent, and drive formulation projects to enhance therapeutic solutions while thriving in a d...
2 weeks ago
Senior Scientific Project Manager
$100K - $130K *
Tackle complex scientific projects by overseeing biopharmaceutical assay development and validation. Collaborate with teams to ensure timely delivery of quality data, manage vendor relationships, and...
1 week ago
$120K - $145K *
Partner with us to drive innovation in peptide chemistry, leveraging your expertise to shape strategic business development, enhance product offerings, and establish key industry relationships while e...
3 days ago
$90K - $120K *
Join a dynamic team providing critical support for CBRD medical systems in a government laboratory. Leverage your expertise in analytical chemistry and program analysis to enhance Navy capabilities in...
3 weeks ago
Sr. Scientist /Scientist - Pharmaceutical Drug Development
$90K - $120K *
Join a dynamic team to drive pharmaceutical drug development through innovative research, overseeing processes from pre-formulation to technology transfer, ensuring compliance with regulatory standard...
Reposted 2 weeks ago
$120K - $145K *
Lead innovative synthetic chemistry projects that drive scalable, manufacturable solutions in specialty chemicals. Collaborate with cross-functional teams to translate research into practical applicat...
Reposted 4 days ago
$120K - $145K *
Join a dynamic team of researchers to develop and optimize cutting-edge polymer-based solutions for the pharmaceutical industry, ensuring scalable and manufacturable innovations while mentoring junior...
Reposted 4 days ago
Senior Scientist, Formulation and DP Development
$155K - $168K *
Champion the development of innovative formulations for biologics, overseeing robust manufacturing processes. Collaborate across teams to support product development initiatives in a dynamic environme...
2 weeks ago
Principal Scientist, Computational Chemistry
$165K - $190K *
Drive innovative drug design as an Experienced Computational Chemist, leveraging molecular modeling and data-driven insights to influence discovery programs. Collaborate with multidisciplinary teams a...
Reposted 2 weeks ago
$110K - $135K *
Lead purification process development from design to execution, mentoring a team to solve scientific challenges. Interface with clients, ensuring high standards in technical and regulatory aspects whi...
3 weeks ago
Principal Scientist, Synthetic Molecule Process Chemistry, Genentech Research
$144K - $269K *
Inspire innovation and advancement in pharmaceutical chemistry by developing processes for API manufacturing. Lead collaborative efforts in early development phases to ensure compliance with regulator...
3 weeks ago
Principal Scientist (Cell Line Development)
$150K - $213K *
Join a team that's advancing biotherapeutics by developing high-performing CHO cell lines for clinical-grade manufacturing, utilizing your expertise in recombinant antibody production and purification...
2 weeks ago
$120K - $147K *
Lead innovative product development initiatives within dental chemical consumables. Drive experiments, validate performance, and ensure quality compliance while collaborating with cross-functional tea...
Today
$90K - $120K *
Transform innovative concepts into delicious consumer products by leading product development projects across diverse confectionery categories, leveraging strong technical expertise and cross-function...
2 weeks ago
$90K - $110K *
Grow your career with an innovative role in researching novel materials, focusing on plasmonic and nanocrystalline technologies. Lead R&D projects and mentor junior staff in a dynamic lab and field en...
1 week ago
$90K - $110K *
Join a dynamic team to research and develop novel materials focusing on advanced applications in aerosol science and electro-optical analysis, while mentoring junior staff and contributing to impactfu...
1 week ago
Principal Scientist, Early Pipeline Development
$108K - $201K *
Champion innovative downstream purification processes for AAV gene therapy. Oversee process development while leading a dedicated team and collaborating across functions to advance pipeline projects f...
2 weeks ago
$90K - $130K *
Unlock your potential as a senior scientist, leading the advancement of innovative 3D organoid model systems. Collaborate cross-functionally to translate scientific discoveries into impactful solution...
2 weeks ago
Senior Scientist, Functional Genomics
$136K - $170K *
Champion groundbreaking in vivo CRISPR screening initiatives and lead innovative genetic research projects that drive therapeutic discoveries through high-throughput functional genomics and advanced t...
Yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.