Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$80K - $109K *

Explore a role that encourages curiosity and growth by leading impactful ADME projects, collaborating with experts, and driving innovative research methodologies in a dynamic team environment...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Champion innovation by driving scientific research, product development, and cross-functional coordination to enhance early-stage evaluation and project management efforts in tissue regeneration and a...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$288K - $420K *

Reimagine the future of materials science by leading a team in developing agentic AI systems. Own the scientific rigor and technical direction to drive innovations from research to production, ultimat...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$288K - $420K *

Lead the charge in developing agentic AI systems for materials science, setting technical direction, mentoring a team, and integrating cutting-edge research with practical applications. Drive innovati...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$174K - $213K *

Champion regulatory excellence in food safety and nutrition, leveraging deep expertise to guide clients through complex compliance challenges and develop impactful strategies for product approvals and...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$170K - $185K *

Unlock your potential by leading the cell potency analytical development team. Drive strategic initiatives to develop and optimize assays for NK cell therapies while mentoring a talented group of scie...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $180K *

Join a team that's pioneering high-concentration biologics formulation. Lead innovative strategies, mentor talent, and drive formulation projects to enhance therapeutic solutions while thriving in a d...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Tackle complex scientific projects by overseeing biopharmaceutical assay development and validation. Collaborate with teams to ensure timely delivery of quality data, manage vendor relationships, and...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Partner with us to drive innovation in peptide chemistry, leveraging your expertise to shape strategic business development, enhance product offerings, and establish key industry relationships while e...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Join a dynamic team providing critical support for CBRD medical systems in a government laboratory. Leverage your expertise in analytical chemistry and program analysis to enhance Navy capabilities in...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K - $120K *

Join a dynamic team to drive pharmaceutical drug development through innovative research, overseeing processes from pre-formulation to technology transfer, ensuring compliance with regulatory standard...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead innovative synthetic chemistry projects that drive scalable, manufacturable solutions in specialty chemicals. Collaborate with cross-functional teams to translate research into practical applicat...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a dynamic team of researchers to develop and optimize cutting-edge polymer-based solutions for the pharmaceutical industry, ensuring scalable and manufacturable innovations while mentoring junior...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$155K - $168K *

Champion the development of innovative formulations for biologics, overseeing robust manufacturing processes. Collaborate across teams to support product development initiatives in a dynamic environme...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $190K *

Drive innovative drug design as an Experienced Computational Chemist, leveraging molecular modeling and data-driven insights to influence discovery programs. Collaborate with multidisciplinary teams a...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Lead purification process development from design to execution, mentoring a team to solve scientific challenges. Interface with clients, ensuring high standards in technical and regulatory aspects whi...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$144K - $269K *

Inspire innovation and advancement in pharmaceutical chemistry by developing processes for API manufacturing. Lead collaborative efforts in early development phases to ensure compliance with regulator...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $213K *

Join a team that's advancing biotherapeutics by developing high-performing CHO cell lines for clinical-grade manufacturing, utilizing your expertise in recombinant antibody production and purification...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $147K *

Lead innovative product development initiatives within dental chemical consumables. Drive experiments, validate performance, and ensure quality compliance while collaborating with cross-functional tea...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Transform innovative concepts into delicious consumer products by leading product development projects across diverse confectionery categories, leveraging strong technical expertise and cross-function...

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$90K - $110K *

Grow your career with an innovative role in researching novel materials, focusing on plasmonic and nanocrystalline technologies. Lead R&D projects and mentor junior staff in a dynamic lab and field en...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $110K *

Join a dynamic team to research and develop novel materials focusing on advanced applications in aerosol science and electro-optical analysis, while mentoring junior staff and contributing to impactfu...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$108K - $201K *

Champion innovative downstream purification processes for AAV gene therapy. Oversee process development while leading a dedicated team and collaborating across functions to advance pipeline projects f...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Unlock your potential as a senior scientist, leading the advancement of innovative 3D organoid model systems. Collaborate cross-functionally to translate scientific discoveries into impactful solution...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $170K *

Champion groundbreaking in vivo CRISPR screening initiatives and lead innovative genetic research projects that drive therapeutic discoveries through high-throughput functional genomics and advanced t...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.