Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$156K - $247K *

Lead and mentor a Human Factors team, driving compliance and innovation in product design through human-centered methodologies and extensive cross-functional collaboration throughout the product lifec...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Manage a Human Factors team to ensure compliance with global regulatory policies for medical devices, leading comprehensive assessments across product lifecycles and collaborating with cross-functiona...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $247K *

Lead the charge in advancing Human Factors initiatives across product lifecycles. Manage a team of skilled scientists to ensure product compliance and user-centric design while collaborating with cros...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $138K *

Unlock potential by developing and executing ligand binding assays to support pharmacokinetic and pharmacodynamic studies in a collaborative, fast-paced lab environment with cross-functional teams. Ma...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's pioneering advanced solid-state solutions for pharmaceutical molecules, focusing on innovative solid form screening approaches and collaborative project efforts to elevate drug form...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Unlock the potential of drug discovery by leading medicinal chemistry initiatives, from compound design to purification, while collaborating closely with biology teams to enhance therapeutic efficacy...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Lead a high-performing team driving innovative vaccine process development, providing strategic scientific leadership for polysaccharide fermentation and purification. Influence key decisions from dev...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $128K *

Advance upstream process development for biologic proteins, collaborating with cross-functional teams to optimize, scale-up, and transfer innovative solutions in a cGMP environment, ensuring quality a...

Burnaby, BCIn-Person

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $190K *

Shape the future of acquisition management by leading transformational programs, optimizing operational effectiveness, and ensuring compliance with regulatory standards to enhance mission success for...

2 weeks ago

  •   15+ years exp.  •   Aerospace & Defense

$66K - $171K *

Drive technical excellence in peptide manufacturing processes, ensuring compliance with global standards. Collaborate with internal and external teams to resolve issues and promote continuous improvem...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$66K - $171K *

Accelerate your career in a dynamic environment, providing scientific expertise to ensure compliance and reliability in pharmaceutical manufacturing processes across external partners and uphold globa...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$198K - $241K *

Transform antibody discovery by merging cutting-edge computational design with innovative wet-lab practices. Lead and collaborate with teams to ensure scientific integrity and advance biologic drug de...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Join us to lead global regulatory strategies in the Vaccines and Infectious Disease area, ensuring compliance and optimal approval timelines. Collaborate cross-functionally, directly engage with regul...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Transform global regulatory strategies for vaccines and infectious diseases, ensuring compliance and expedited approvals. Collaborate cross-functionally, lead regulatory teams, and engage with agencie...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Partner with us to optimize our chromatography purification fleet utilizing SFC-MS and LC-MS systems. Develop, standardize, and manage high-throughput purification methods crucial for accelerating dru...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $178K *

Develop analytical methods and lead validation processes for GMP biotherapeutics. Collaborate across teams to solve technical issues and ensure compliance with regulations while preparing for clinical...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead process development to scale-up and transfer technology for peptide synthesis. Play a key role in the commercialization of innovative products within pharmaceutical and beauty sectors, collaborat...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Lead formulation and process development for drug product initiatives, enhancing lifecycle management and innovative strategies. Collaborate with teams to deliver novel and existing formulations for o...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $201K *

Innovate by leading bench research in biomarker assay development for preclinical and clinical programs. Collaborate with cross-functional teams to ensure rigorous, impactful strategies across diverse...

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $165K *

Advance biomolecular characterization by pioneering antibody-target binding techniques, leveraging expertise in BLI and SPR with a collaborative team focused on innovative research and impactful disco...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$151K - $175K *

Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $277K *

Lead strategic DMPK initiatives across diverse projects in immunology and oncology. Collaborate with multi-disciplinary teams to optimize the drug development process and ensure seamless integration o...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $179K *

Shape the future of analytical chemistry! Lead projects across R&D, commercial activities, and cross-functional teams. Oversee lab practices, enhance methodologies, and ensure compliance while mentori...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$72K - $120K *

Join a dynamic team as a Senior Scientist, leading advanced diagnostic tests and mentoring junior staff. Drive laboratory method improvements while ensuring accuracy and compliance in a collaborative...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $107K *

Lead a dynamic research and development team to innovate and enhance products in the Family Care tissue business, ensuring consumer needs are met while collaborating across functions to drive successf...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.