Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$130K - $180K *

Transform customer interactions by developing intelligent, scalable AI-driven agents. Collaborate across teams to enhance workflows, build reliable systems, and integrate advanced AI capabilities into...

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $150K *

Lead the development of advanced laser systems for aerospace applications, guiding teams in engineering and system integration, driving innovation and ensuring compliance with customer specifications...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$90K - $120K *

Drive the development and implementation of cutting-edge chemical processes, ensuring optimal yields and quality. Collaborate with cross-functional teams to explore innovative solutions for scalable m...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Champion innovative dairy solutions by leading projects that enhance product quality and customer satisfaction, applying your technical expertise in enzyme functionality to drive impactful changes acr...

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $155K *

Join a collaborative team to lead innovative research bridging data science and human physiology. Drive analysis of longitudinal datasets to provide actionable insights that influence product developm...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $163K *

Shape the future of clinical studies by leading biomarker and bioanalytical operations to deliver timely, high-quality data. Collaborate with cross-functional teams and external partners to advance dr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$149K - $185K *

Lead the GMP implementation of innovative processes in cell and gene therapy, collaborating with cross-functional teams to ensure scientific integrity and compliance. Drive technology transfer initiat...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Shape the future of product engineering by leading high-performing teams in delivering secure, scalable, and reliable solutions for our customer-facing and internal platforms. Collaborate across disci...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $162K *

Engage in diverse polymer science projects, analyzing materials and performing root cause investigations across multiple industries. Collaborate with interdisciplinary teams and contribute to business...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $164K *

Drive innovation in chemical process design and scale-up, enhancing efficiency and quality. Collaborate globally to transition projects from lab through manufacturing, ensuring safety, compliance, and...

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$160K - $240K *

Lead biomarker development by executing strategies across clinical programs, ensuring assay validation, and guiding interdisciplinary teams and external partnerships. Drive innovative solutions while...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the coordination and management of scientific projects, providing expert support in engineering and automation. Oversee project lifecycle to ensure alignment with strategic goals, delivering impa...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Elevate your career by leading a strategic engineering team, defining technical vision, and driving product delivery in a collaborative, fast-paced environment focused on growth and innovation...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead complex programs connecting customers with operational excellence. Drive high-quality delivery while managing cross-functional teams in a fast-paced, matrixed environment. Inspire collaboration f...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $142K *

Innovate with us as a Materials Scientist, developing cutting-edge materials for 3D printing. Work collaboratively across teams to enhance product performance and drive advancements in various industr...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$148K - $171K *

Lead analytical method development and validation for drug substances and products. Collaborate with cross-functional teams, mentor analysts, and oversee contract activities to contribute to late-phas...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Lead the charge in innovative protein chemistry, driving personal care technologies from concept to market. Collaborate cross-functionally, utilizing expertise in protein modifications and advance ana...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Lead the charge in developing innovative functional beverage formulations, from initial prototype to production-ready, emphasizing analytical rigor and sensory evaluation while navigating complex ingr...

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$70K - $95K *

Empower progress at the forefront of environmental protection by conducting site assessments, analyzing data, and recommending remediation strategies to ensure compliance with regulations while collab...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$90K - $120K *

Champion project execution by coordinating lab research, managing client needs, and ensuring quality standards are met. Oversee budgets, schedule activities, and lead technical teams while optimizing...

Quebec, QCIn-Person

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$143K - $194K *

Transform drug development by leading the creation of LC-MS-based assays to quantify therapeutics and biomarkers, driving innovation and collaboration in cross-functional research teams to enhance the...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $148K *

Unlock potential by leading the development of advanced flow cytometry and ligand-binding assays, collaborating with multidisciplinary teams to enhance clinical biomarker strategies and drug developme...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $343K *

Empower the advancement of digital pathology by developing innovative image-analysis solutions using cutting-edge machine learning and deep learning techniques to drive significant insights in drug di...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Engage in a global leadership program that deepens technical expertise and fosters local team development. Spend two years in China mastering technology transfer, then lead international projects and...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive global leadership development by mastering biopharmaceutical processes in China before leading technology transfer at overseas sites. Engage in high-impact projects, process scale-up, and establ...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.