Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Research Scientist, Photonic Materials Discovery
$176K - $304K *
Lead the charge in computational materials discovery, optimizing electro-optic and photonic technologies. Collaborate across disciplines to develop innovative, validated workflows that translate mater...
3 weeks ago
Lead Principal Program Manager
$116K - $264K *
Engage as a Senior Principal Technical Program Manager to lead complex, cross-functional programs driving OCI's global infrastructure initiatives, enhancing efficiency through AI, and steering executi...
6 days ago
Lead Principal Program Manager
$116K - $264K *
Lead the charge in driving strategic, large-scale infrastructure initiatives across cloud operations. Collaborate with cross-functional teams to enhance AI-driven efficiencies, governance, and deliver...
6 days ago
Principal Scientist (Director), Outcomes Research, Pediatric Vaccines
$190K - $300K *
Champion impactful outcomes research in pediatric vaccines, driving value evidence plans and real-world evidence studies in collaboration with cross-functional teams and external stakeholders for opti...
1 week ago
Clinical Research, Senior Principal Scientist (Director), Oncology
$172K - $287K *
Empower oncology research and clinical development by leading strategic initiatives and executing groundbreaking studies. Collaborate with cross-functional teams to translate insights into actionable...
Yesterday
Scientific Operations Manager / Associate Scientist, Oligonucleotide Synthesis & Analytical Sciences
$100K - $125K *
Shape the future of genetic medicine by managing lab operations and conducting oligonucleotide chemistry in a fast-paced environment. Drive efficiency in synthesis and quality control while directly i...
2 weeks ago
(Senior / Principal) Scientist, Peptide Chemistry (Night Shift)
$120K - $145K *
Grow your career with an opportunity to lead peptide synthesis overnight, making critical technical decisions and ensuring seamless transitions for day teams, while addressing complex chemistry challe...
1 week ago
Research Scientist - Skin Biologist
$85K - $110K *
Advance your career by designing and leading innovative skin biology research that drives the development of cutting-edge personal care ingredients, influencing product strategies and customer solutio...
Reposted 3 weeks ago
Research Scientist - Skin Biologist
$85K - $110K *
Unlock potential by leading innovative skin biology research to enhance personal care products. Collaborate with cross-functional teams to design impactful studies and drive the development of next-ge...
Reposted 3 weeks ago
Scientist II, Pharmaceutical Development
$110K - $151K *
Empower pharmaceutical development by designing analytical methods and conducting preformulation studies for novel therapeutics. Collaborate with multidisciplinary teams to identify risks and communic...
1 week ago
$110K - $130K *
Shape innovative hydrometallurgical processes by executing experiments, analyzing data, and optimizing extraction techniques for critical minerals in a hands-on laboratory and pilot-scale environment...
4 days ago
Process Development Senior Scientist
$126K - $170K *
Elevate your career by joining a cutting-edge team focused on inventing and optimizing drug manufacturing processes. Apply your expertise in organic chemistry to drive innovation and ensure the delive...
Reposted 4 days ago
Process Development Senior Scientist
$126K - $170K *
Drive innovative drug substance processes for commercial advancement, working collaboratively in a dynamic environment. Contribute to the development and optimization of bioprocesses across various mo...
1 week ago
Process Development Senior Scientist
$126K - $170K *
Advance the development of biologics formulations by leveraging expertise in ADCs, collaborating cross-functionally to produce high-quality drug products while utilizing advanced technologies like AI...
2 weeks ago
Senior Research Scientist (m/f/d)
$135K - $160K *
Unlock potential by advancing cutting-edge Vision-Language-Action models for robotics, pioneering research that bridges the gap between theory and real-world applications, and enhancing AI-driven robo...
3 weeks ago
Principal Engineer - Device/Combination Product Sterilization
$109K - $203K *
Empower innovation in healthcare by leading sterilization strategy, validation, and compliance for medical devices. Collaborate across teams to enhance product quality and ensure safety standards thro...
1 week ago
Principal Engineer - Device/Combination Product Sterilization
$109K - $203K *
Join a team that's dedicated to improving healthcare solutions by leading sterilization processes and collaborating with cross-functional experts throughout the product lifecycle, ensuring quality and...
1 week ago
Scientist (Multi-specific Antibody Development)
$110K - $130K *
Deliver impactful scientific leadership as you drive the discovery, optimization, and validation of multi-specific T-cell engagers, advancing therapeutic solutions through innovative assays and cross...
Reposted 3 weeks ago
Senior Managing Regulatory Scientist (Ph.D. or M.S.)
$174K - $200K *
Pioneer in regulatory science and project management; lead strategies for Federal and State pesticide registrations while cultivating new client relationships and mentoring junior staff in a collabora...
4 weeks ago
Sr Scientist II, Computational Discovery Science
$145K - $190K *
Join our dynamic team to leverage your expertise in computational methods for drug discovery. You'll drive scientific strategy and execution, collaborate with cross-functional teams, and communicate f...
6 days ago
Sr Scientist II, Computational Discovery Science
$145K - $190K *
Partner with us to drive innovation in cancer therapeutic discovery by applying advanced computational techniques to multi-modal datasets, collaborating with interdisciplinary teams to uncover new bio...
6 days ago
$120K - $145K *
Transform technology solutions and architecture by leading complex projects. Collaborate with stakeholders to define business requirements, ensuring delivery of innovative application technologies tha...
1 week ago
$218K - $272K *
Lead cross-functional teams to architect and deliver innovative application solutions, ensuring alignment with strategic objectives while driving technology evolution and integration across diverse pl...
1 week ago
$130K - $155K *
Transform technology solutions by leading end-to-end application architecture, collaborating with stakeholders, and delivering innovative products. Drive strategic initiatives to align technology with...
1 week ago
$125K - $150K *
Help us shape the future of technology by leading the architecture and design of enterprise-wide applications. Collaborate with stakeholders to drive technical excellence and innovation across multipl...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.