Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$90K - $110K *

Unlock potential as a Senior Biologist, leading complex terrestrial ecology projects, managing client relationships, and delivering impactful environmental solutions while mentoring future talent in a...

Calgary, ABIn-Person

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Innovate new formulations for sanitizers in the dairy and food industries. Lead research projects, develop analytical methods, and ensure regulatory compliance. Collaborate with teams to bring success...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $185K *

Advance your career by developing cutting-edge membrane technologies for semiconductor applications. Collaborate with cross-functional teams to innovate, optimize processes, and support product launch...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Transform production operations through effective scheduling, team leadership, and continuous improvement in a cleanroom environment. Drive performance metrics while ensuring compliance with quality s...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform your career by leading an evolving PMO, ensuring excellence in project delivery, harmonizing processes, and supporting customer satisfaction in a dynamic environment...

Reposted yesterday

  •   11 - 15 years exp.  •   Technical Services

$150K - $180K *

Lead and enhance project execution across global teams, ensuring top-tier customer satisfaction and consistent delivery. Drive strategic process unification and elevated performance as you shape the P...

Reposted yesterday

  •   11 - 15 years exp.  •   Consumer Technology

$100K - $155K *

Join a team that's dedicated to optimizing bioprocess technologies. Leverage your expertise in cell culture and bioprocessing to deliver technical support and solutions for customers, enhancing their...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Make your mark at the intersection of science and patient impact by leading analytical development and QC for late-stage programs, ensuring rigorous compliance and innovation across various biologics...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $132K *

Elevate your career by owning PCR and digital PCR assay development, optimizing strategies, leading troubleshooting efforts, and ensuring data quality to support innovative diagnostic projects in a co...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive laboratory excellence by maintaining, calibrating, and qualifying lab instrumentation. Collaborate with staff to ensure compliance with GMP safety standards while providing training and document...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $400K *

Drive innovation in AI safety by building robust safeguards for conversational agents. Collaborate across teams to enhance model reliability and mitigate real-world risks, creating impactful solutions...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$200K - $400K *

Join a team that's advancing AI safety by building reliable, controllable models for conversational agents. Collaborate across functions to transform safety challenges into scalable, production-ready...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$68K - $114K *

Join a dynamic Process Chemistry team to develop scalable methods for pharmaceutical APIs. Engage in hands-on synthesis of small molecules, peptides, and lipids while collaborating across disciplines...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $114K *

Support early vaccine development by conducting routine sample testing, assay verification, and data analysis in a laboratory setting. Collaborate on method development and general laboratory maintena...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$127K - $170K *

Drive advancements in cell therapy through in vivo studies and preclinical model development. Collaborate with cross-functional teams to generate data that informs drug development and expand therapeu...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $211K *

Inspire innovative microbiological and viral safety testing leadership, ensuring strategic support for development programs. Collaborate cross-functionally to drive efficiency, manage risk, and advanc...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $109K *

Lead the charge in managing environmental projects from assessment to remediation, ensuring compliance, client communication, and budget management while mentoring junior staff and collaborating with...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$268K - $358K *

Accelerate your career by leading applied ML initiatives that drive innovations in protein engineering, biomolecular design, and therapeutic solutions. Collaborate with experts to enhance AI methods f...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $145K *

Drive method development and QC testing for gene therapies in a GMP environment, ensuring compliance and timely results to support product progression. Collaborate effectively with cross-functional te...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $335K *

Innovate cutting-edge training infrastructure for frontier reinforcement learning, optimizing pipelines and enhancing system reliability. Collaborate closely with researchers to ensure efficient model...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$109K - $164K *

Transform the future of product development by leading R&D projects focused on advanced electronic inks and pastes, collaborating with global teams to deliver high-quality innovations on time and with...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Advance your career by leading innovative research and development initiatives in production maximization to create impactful solutions for customers, while fostering a collaborative team environment...

Calgary, ABIn-Person

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to innovative production chemistry solutions that maximize oil and gas production. Lead complex research, drive development projects, and collaborate with teams to enhance operational effic...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$193K - $420K *

Unlock potential by designing the semantic infrastructure that enhances AI agents with accurate enterprise context, transforming data into actionable knowledge for superior decision-making in complex...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Develop innovative precursor molecules for high-tech industries; collaborate with multidisciplinary teams to enhance deposition processes in semiconductor, automotive, aerospace, and healthcare applic...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.