Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$90K - $100K *
Unlock potential by leading the development, validation, and commercialization of innovative food products. Collaborate across functions to drive quality, safety, and efficiency while managing complex...
1 week ago
$90K - $100K *
Lead the charge in the development and commercialization of innovative food products. Collaborate cross-functionally, applying advanced food science techniques to meet consumer needs and ensure compli...
1 week ago
$173K - $272K *
Lead transformative projects by leveraging digital technologies to enhance lab automation, data integration, and scientific workflows, enabling innovative research in pharmaceutical development across...
Reposted 1 week ago
$173K - $272K *
Join a team that's shaping the future of pharmaceutical development through digital technologies. As a Principal Scientist, you'll innovate automation and semantic systems, driving impactful solutions...
Reposted 1 week ago
Principal Scientist, CMC Analytical
$150K - $190K *
Unlock potential by leading analytical strategies for drug development, ensuring robust quality control throughout product lifecycle. Collaborate with partners to deliver exceptional insights that dri...
2 weeks ago
Principal Research Scientist - Risk
$150K - $180K *
Lead transformative research in infrastructure risk and resilience. Develop advanced models, drive decision-making, and guide a team to improve utility management practices and safeguard critical asse...
5 days ago
Principal AI Scientist and Lead
$130K - $180K *
Lead the development of innovative AI solutions in preclinical research, managing complex predictive models and agentic systems. Collaborate with stakeholders to ensure secure deployment and complianc...
Reposted 6 days ago
Principal Scientist, Technical Services
$110K - $150K *
Lead the charge in pharmaceutical innovations by providing technical expertise for solid oral dosage products, ensuring efficient manufacturing and continuous process improvements throughout the produ...
3 days ago
Senior Scientist, Protein Engineering
$150K - $170K *
Transform the future of protein therapeutics by engineering cutting-edge antibodies and proteins. Collaborate with cross-functional teams to advance drug discovery through innovative strategies and de...
2 weeks ago
Senior / Principal Scientist, Biochemistry
$158K - $184K *
Join a team that's dedicated to advancing drug discovery by designing and implementing innovative biochemical assays to characterize small molecule interactions and drive lead optimization in a collab...
4 days ago
$120K - $140K *
Join a team that's engaged in cutting-edge research to advance life sciences. In this role, you will drive innovative studies, mentor peers, and solve complex problems while contributing to new techno...
2 weeks ago
Senior Scientist, Process Development (AAV)
$151K - $157K *
Empower the future of gene therapy by leading AAV manufacturing process development and optimization. Contribute to CMC activities and collaborate across functions to enhance product quality and regul...
2 weeks ago
$105K - $130K *
Champion product development by leading R&D projects for Adult and Feminine Care. Collaborate across teams to ensure innovative solutions align with market needs while mentoring junior developers...
1 week ago
Senior Scientist, Research & Development
$105K - $148K *
Elevate your career by leading innovative research in oral care and immune response. Collaborate within cross-functional teams to drive scientific advancements and influence product development while...
Reposted today
$95K - $115K *
Drive innovation and product development by leveraging confectionery expertise and scientific methods, leading cross-functional projects to create impactful solutions and enhance product quality withi...
Today
Senior Scientist, Protein Production
$93K - $183K *
Lead the charge in innovative protein science to drive structure-guided drug discovery. Collaborate with cross-disciplinary teams to develop protein constructs, execute expression and purification met...
Reposted 3 weeks ago
Senior Scientist, Fermentation - IR&D, Product Development
$120K - $150K *
Champion innovation in upstream fermentation development, driving collaboration across teams to optimize processes for novel vectors. Utilize advanced technologies to enhance product solutions and sup...
Reposted 4 days ago
Principal Scientist, Lab Platform Disruptive Technologies
$194K - $305K *
Shape the future of biologics discovery by leading innovative lab technologies to enhance data-driven methods and drive impactful therapeutic advancements through team collaboration and hands-on devel...
1 week ago
Senior Scientist, Analytical Research & Development
$90K - $120K *
Drive analytical excellence in product development and validation, overseeing method execution, data integrity, and cross-functional collaborations in a fast-paced environment. Your expertise will be...
3 weeks ago
Senior Scientist 2, Chemical Development & Manufacturing
$120K - $145K *
Shape the future of chemical development by leading cross-functional teams, driving strategic initiatives, and managing high-impact clinical programs. Collaborate closely with various departments to e...
5 days ago
Principal Scientist (Computational Chemistry)
$144K - $269K *
Engage in advanced computational chemistry to drive induced proximity small molecule discovery, collaborating with multidisciplinary teams to optimize candidates and accelerate the drug discovery pipe...
3 weeks ago
Principal Chemist - IPS-Synthesis & API Mfg
$117K - $125K *
Join a team that's revolutionizing small molecule synthesis and API manufacturing. As a key contributor, you'll develop and optimize processes while ensuring compliance and delivering high-quality dru...
Reposted 1 week ago
$90K - $130K *
Join a dynamic team to lead strategic business development in the ecological and biological sciences domain, focusing on regulatory initiatives and sustainable strategies while delivering technical su...
2 weeks ago
Principal Scientist, Process Chemistry
$120K - $170K *
Champion innovative solutions in process chemistry. Lead complex projects, provide scientific mentorship, and drive API development in a collaborative environment while ensuring compliance and quality...
3 weeks ago
$80K - $109K *
Explore a role that encourages curiosity and growth by leading impactful ADME projects, collaborating with experts, and driving innovative research methodologies in a dynamic team environment...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.