Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Senior Principal Scientist, Pre-Formulation and Materials Science
$124K - $207K *
Drive early-stage drug design and delivery as a Senior Principal Scientist, providing leadership and scientific strategy across multi-disciplinary teams to optimize molecular and drug formulation stra...
2 weeks ago
Principal Scientist, Clinical Biomarkers
$140K - $187K *
Drive biomarker strategy for clinical studies, ensuring data quality and compliance. Collaborate across functions and external partners to enhance clinical outcomes in solid organ transplant research...
1 week ago
$130K - $150K *
Unlock potential by joining a dynamic R&D team as a Senior Scientist in DMPK. Lead drug development through strategic planning, research execution, and collaboration to drive therapies from discovery...
1 month ago
Senior Scientist, Computational Safety
$140K - $222K *
Lead the charge in developing advanced AI/ML models for predictive toxicity assessments. Collaborate with cross-functional teams to integrate multi-modal biological data, driving insights that improve...
3 weeks ago
$100K - $130K *
Champion advanced sterile manufacturing processes, driving optimization and compliance in liquid and lyophilized parenteral operations while collaborating cross-functionally to enhance performance and...
2 weeks ago
Senior Scientist - BioAnalytical Research
$71K - $213K *
Transform the field of radioligand therapeutics through innovative small molecule mass spectrometry bioanalysis, enhancing drug discovery efforts by supporting project teams in evaluating ADME propert...
2 weeks ago
$92K - $95K *
Elevate the science of Analytical Development by leading method development, experimentation, and problem-solving for complex studies, ensuring robust and compliant results in a fast-paced lab environ...
6 days ago
Senior Scientist- Process Chemistry
$158K - $214K *
Accelerate progress at the forefront of chemistry and manufacturing, driving the development and optimization of innovative processes. Collaborate cross-functionally, troubleshooting and enhancing che...
Reposted 5 days ago
Principal Scientist, Protein Engineering
$176K - $277K *
Champion innovative drug discovery by leading a team in protein engineering to develop next-gen biotherapeutics, fostering collaboration across multifunctional therapeutic areas from conception throug...
Reposted 6 days ago
$90K - $120K *
Collaborate to advance protein biochemistry through innovative research techniques, driving impactful results in molecular cloning, protein purification, and biophysical characterization in a dynamic...
2 weeks ago
Principal Scientist, Analytical Development, Oligo and Small Molecule
$165K - $185K *
Champion the transition of analytical methods from lab to manufacturing, ensuring the delivery of innovative neurological therapies through close collaboration across teams and management of external...
Reposted 2 weeks ago
$95K - $133K *
Champion technical operations for liquid dosage pharmaceuticals, ensuring compliance and excellence in manufacturing, scale-up, and technology transfer while building strong cross-functional teams and...
Yesterday
Principal Scientist, Antibody Engineering & Rational Design
$198K - $241K *
Transform antibody discovery by merging cutting-edge computational design with innovative wet-lab practices. Lead and collaborate with teams to ensure scientific integrity and advance biologic drug de...
2 weeks ago
Senior Scientist - Manufacturing Science
$66K - $171K *
Unlock potential by providing technical expertise in API manufacturing to enhance process control, yield, and productivity, executing projects independently while supporting documentation and validati...
1 week ago
$100K - $130K *
Play a key role in advancing laboratory instrumentation and optimizing processes. Collaborate across projects, driving innovation while ensuring compliance and enhancing data quality through rigorous...
Reposted 2 days ago
$120K - $145K *
Shape innovative solutions in cell line development for product and custom projects. Collaborate with a dynamic R&D team to validate assays and support client needs while maintaining high quality stan...
3 days ago
Senior Scientist - Process Modelling
$100K - $145K *
Innovate by developing dynamic bioreactor models to optimize recombinant protein production. Collaborate cross-functionally, maintain robust workflows, and communicate insights effectively while drivi...
1 week ago
$90K - $98K *
Pioneer innovative hair care developments, leading projects from concept to market while collaborating across teams. Utilize advanced formulation technologies and mentor junior scientists to enhance p...
3 weeks ago
Senior Scientist I, Purification Process Development
$126K - $137K *
Elevate biotherapeutic manufacturing through leading innovative purification process development. Join a dynamic team focused on advancing continuous processing technology for cost-effective, scalable...
2 days ago
$90K - $120K *
Transform innovative concepts into market-ready confectionary VMS and OTC products. Lead R&D, mentor junior staff, and collaborate cross-functionally to enhance formulation quality and drive product s...
2 weeks ago
Senior Scientist, Formulation Development
$85K - $112K *
Take ownership of product development, solving complex challenges to ensure stability in pharmaceutical manufacturing, while collaborating with cross-functional teams to execute innovative research pr...
2 days ago
Principal Scientist, Pharmaceutical Development
$130K - $179K *
Lead the charge in CMC project management within Pharmaceutical Development, driving drug product development from early discovery to commercialization. Collaborate cross-functionally to ensure high-q...
1 week ago
Principal Scientist - AI-Powered Discovery for Neurodegeneration
$122K - $176K *
Drive advancements in neurology by leading AI/ML-based research initiatives. Spearhead the analysis of large datasets to uncover disease mechanisms in neurodegenerative disorders, while fostering coll...
3 weeks ago
$100K - $125K *
Lead the charge in pioneering innovative process chemistries and cementitious materials, emphasizing the development of new reactions and optimized formulations to drive product performance in a dynam...
2 weeks ago
$102K - $171K *
Join a team that's dedicated to advancing bioproducts through innovative process development for recombinant proteins. Embrace hands-on laboratory work, collaborate across functions, and drive impactf...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.