Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$90K - $100K *

Unlock potential by leading the development, validation, and commercialization of innovative food products. Collaborate across functions to drive quality, safety, and efficiency while managing complex...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $100K *

Lead the charge in the development and commercialization of innovative food products. Collaborate cross-functionally, applying advanced food science techniques to meet consumer needs and ensure compli...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$173K - $272K *

Lead transformative projects by leveraging digital technologies to enhance lab automation, data integration, and scientific workflows, enabling innovative research in pharmaceutical development across...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Join a team that's shaping the future of pharmaceutical development through digital technologies. As a Principal Scientist, you'll innovate automation and semantic systems, driving impactful solutions...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $190K *

Unlock potential by leading analytical strategies for drug development, ensuring robust quality control throughout product lifecycle. Collaborate with partners to deliver exceptional insights that dri...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead transformative research in infrastructure risk and resilience. Develop advanced models, drive decision-making, and guide a team to improve utility management practices and safeguard critical asse...

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $180K *

Lead the development of innovative AI solutions in preclinical research, managing complex predictive models and agentic systems. Collaborate with stakeholders to ensure secure deployment and complianc...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $150K *

Lead the charge in pharmaceutical innovations by providing technical expertise for solid oral dosage products, ensuring efficient manufacturing and continuous process improvements throughout the produ...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $170K *

Transform the future of protein therapeutics by engineering cutting-edge antibodies and proteins. Collaborate with cross-functional teams to advance drug discovery through innovative strategies and de...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$158K - $184K *

Join a team that's dedicated to advancing drug discovery by designing and implementing innovative biochemical assays to characterize small molecule interactions and drive lead optimization in a collab...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Join a team that's engaged in cutting-edge research to advance life sciences. In this role, you will drive innovative studies, mentor peers, and solve complex problems while contributing to new techno...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$151K - $157K *

Empower the future of gene therapy by leading AAV manufacturing process development and optimization. Contribute to CMC activities and collaborate across functions to enhance product quality and regul...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Champion product development by leading R&D projects for Adult and Feminine Care. Collaborate across teams to ensure innovative solutions align with market needs while mentoring junior developers...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $148K *

Elevate your career by leading innovative research in oral care and immune response. Collaborate within cross-functional teams to drive scientific advancements and influence product development while...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive innovation and product development by leveraging confectionery expertise and scientific methods, leading cross-functional projects to create impactful solutions and enhance product quality withi...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$93K - $183K *

Lead the charge in innovative protein science to drive structure-guided drug discovery. Collaborate with cross-disciplinary teams to develop protein constructs, execute expression and purification met...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Champion innovation in upstream fermentation development, driving collaboration across teams to optimize processes for novel vectors. Utilize advanced technologies to enhance product solutions and sup...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$194K - $305K *

Shape the future of biologics discovery by leading innovative lab technologies to enhance data-driven methods and drive impactful therapeutic advancements through team collaboration and hands-on devel...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Drive analytical excellence in product development and validation, overseeing method execution, data integrity, and cross-functional collaborations in a fast-paced environment. Your expertise will be...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Shape the future of chemical development by leading cross-functional teams, driving strategic initiatives, and managing high-impact clinical programs. Collaborate closely with various departments to e...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $269K *

Engage in advanced computational chemistry to drive induced proximity small molecule discovery, collaborating with multidisciplinary teams to optimize candidates and accelerate the drug discovery pipe...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $125K *

Join a team that's revolutionizing small molecule synthesis and API manufacturing. As a key contributor, you'll develop and optimize processes while ensuring compliance and delivering high-quality dru...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Join a dynamic team to lead strategic business development in the ecological and biological sciences domain, focusing on regulatory initiatives and sustainable strategies while delivering technical su...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $170K *

Champion innovative solutions in process chemistry. Lead complex projects, provide scientific mentorship, and drive API development in a collaborative environment while ensuring compliance and quality...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $109K *

Explore a role that encourages curiosity and growth by leading impactful ADME projects, collaborating with experts, and driving innovative research methodologies in a dynamic team environment...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.