Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$100K - $275K *
Accelerate project success by leading complex programs in defense technology. Oversee full lifecycle management, ensuring alignment with cost, schedule, and performance targets while developing strong...
2 weeks ago
$100K - $275K *
Lead the charge in program management for complex defense projects, overseeing all lifecycle phases to ensure strategic success. Collaborate with diverse teams, engage with customers, and innovate for...
2 weeks ago
$100K - $275K *
Oversee the execution of complex projects for cutting-edge ICBM technologies, ensuring cost, schedule, and performance targets are met while fostering strong customer relationships and leading high-pe...
2 weeks ago
Scientist / Senior Scientist, Assay Development (Sample Prep)
$90K - $161K *
Innovate by developing and optimizing sample preparation methods for advanced proteomic applications, ensuring quality and scalability in a collaborative lab environment. Engage with diverse biologica...
2 weeks ago
$92K - $166K *
Drive innovation in advanced radar systems by leveraging software development skills. Collaborate with a diverse team of scientists and engineers to analyze and enhance system performance using cuttin...
4 days ago
Associate Scientist, Bioproduction
$85K - $95K *
Join a team that's advancing bioproduction technologies by executing critical upstream bioprocess operations to ensure successful scale-up from synthetic design to large-scale protein production...
3 weeks ago
$72K - $90K *
Elevate project management skills by coordinating environmental lab projects, fostering client relationships, and ensuring accuracy while navigating complex scientific processes to deliver exceptional...
6 days ago
$100K - $275K *
Empower HR success by leading Workday HCM initiatives, integrating solutions, and enhancing user experience. Drive effective reporting and optimize system performance through strategic collaboration w...
1 week ago
Senior Scientist, Hybrid Modeler, Digital Insights, DSCS Digital Technologies
$117K - $184K *
Join our team as a Senior Scientist to advance digital modeling strategies in drug substance and product manufacturing. Utilize CFD and data-driven approaches to optimize processes and drive innovatio...
5 days ago
$90K - $120K *
Join the R&D team to pioneer innovative polymer solutions for high-performance concrete applications, contributing to advanced, sustainable cementitious systems while collaborating across technical an...
1 week ago
$87K - $107K *
Lead materials and process development initiatives for innovative wipes technology, guiding projects from conception through commercialization, while collaborating with global teams to optimize nonwov...
Reposted yesterday
Platform Scientist: Comparative Protein Evolution
$130K - $180K *
Advance your career by developing innovative computational approaches to explore protein evolution. Collaborate within a team to analyze data across non-model clades, contributing to the understanding...
Today
Scientist, Analytical Development
$135K - $155K *
Join a dynamic team, driving innovative analyses in CAR T therapy development to enhance treatment solutions for pediatric brain malignancies, while overseeing method optimization and supporting cross...
3 weeks ago
Research Scientist, Sr. (Protein Immunotherapy)
$95K - $130K *
Research transformative protein immunotherapy solutions as part of an interdisciplinary team. Drive innovative approaches from concept to clinical trials, engaging in next-gen antibody development and...
3 weeks ago
$121K - $181K *
Deliver innovative materials solutions by conducting advanced lab experiments and interfacing with sponsors to tackle critical technical challenges. Contribute to interdisciplinary research while driv...
2 weeks ago
Principal Purification Chemist
$100K - $130K *
Join a team that drives innovation by enhancing purification chemistry and processes from lab scale to full commercialization, leading cross-disciplinary teams to achieve quality and efficiency in GMP...
3 weeks ago
$120K - $150K *
Unlock potential by leading the mechanical design of innovative systems, ensuring effective collaboration across disciplines while managing vendor relationships and guiding product development from pr...
2 weeks ago
$120K - $150K *
Lead clinical trial operations ensuring compliance with regulations and GCP guidelines. Drive quality assurance initiatives and mentor teams, while overseeing audits, training, and CAPA processes to u...
3 weeks ago
Scientist, 3 Antibody Engineering
$103K - $192K *
Engage in cutting-edge antibody engineering to drive the development of novel therapeutics. Leverage your expertise in molecular biology and protein characterization while collaborating with multidisc...
2 weeks ago
Scientist, Oligonucleotide Sciences Analytical Chemistry
$83K - $138K *
Champion the advancement of oligonucleotide therapeutics by performing critical analytical chemistry to ensure quality control and method development for innovative synthetic oligonucleotides, directl...
1 week ago
Scientist, Machine Learning (Principal Scientist - Associate Director)
$130K - $180K *
Drive advancements in small molecule drug discovery by applying cutting-edge machine learning techniques, collaborating closely with multidisciplinary teams to facilitate strategic decisions and optim...
2 weeks ago
Scientist I, ASO Process Development and Manufacturing
$103K - $134K *
Build a bright future in oligonucleotide synthesis by enhancing process efficiency and integrity. Collaborate in a dynamic team to develop robust manufacturing processes that impact therapeutics and i...
Yesterday
Principal Scientist - RGM Chemistry
$128K - $210K *
Transform therapeutic development by leading the design of innovative antibody-oligonucleotide conjugation technologies. Drive cross-functional collaboration and mentor a diverse team to accelerate br...
2 weeks ago
Laboratory Operations Program Manager
$130K - $160K *
Pioneer a transformative role in laboratory operations, managing resources, budgets, and compliance to ensure high-quality performance. Lead strategic initiatives while collaborating across teams to s...
Today
Senior Scientist - Experimental Protein Design for Target Discovery
$131K - $177K *
Partner with us to drive high-throughput binder discovery and lead experimental validation of computationally designed proteins. You’ll create scalable libraries, characterizing innovative tool molecu...
Reposted 3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.