Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist, Chemical Development
$169K - $206K *
Join a team that's advancing innovative cancer therapies. Lead the development of transformative small molecule processes while collaborating cross-functionally, shaping drug development strategies, a...
3 weeks ago
Scientist, IVD Product Development & Validation
$100K - $120K *
Empower our team in driving innovation by designing and executing analytical validation studies, ensuring regulatory compliance, and collaborating with cross-functional teams to advance NGS-based IVD...
2 weeks ago
Manufacturing Science & Technology (MS&T) Scientist
$88K - $105K *
Drive product and technology transfer success through process optimization and team leadership in pharmaceutical manufacturing. Collaborate across departments to support innovative solutions for solid...
Reposted 3 weeks ago
$75K - $113K *
Pioneer quality assurance initiatives by executing analytical testing and leading investigations. Collaborate with cross-functional teams to enhance product compliance and drive continuous improvement...
2 weeks ago
Senior Technical Specialist, Sample Management
$88K - $105K *
Drive your career with us as a Senior Technical Specialist, where you will enhance Sample Management processes, lead cross-functional projects, and collaborate with experts to deliver high-quality sol...
2 weeks ago
Senior Technical Specialist, Sample Management
$88K - $105K *
Champion effective Sample Management by leading process improvements, collaborating across teams, and providing technical expertise to ensure high-quality service delivery and operational efficiency i...
2 weeks ago
Senior Clinical Research Scientist
$114K - $228K *
Elevate clinical research by leading evaluations of new product innovations, guiding cross-functional teams, and ensuring compliance with regulatory standards while fostering relationships with stakeh...
1 week ago
Principal Research Scientist - Vision AI, Simulation & Physical AI
$200K - $300K *
Shape the future of embodied intelligence by leading groundbreaking research in Vision AI and multimodal foundation models. Collaborate with a dynamic team to create innovative solutions that advance...
Reposted 1 week ago
$152K - $190K *
Partner with us to design and develop cutting-edge web applications, influencing architecture and engineering standards in a collaborative environment while mentoring others and applying AI capabiliti...
4 days ago
$95K - $115K *
Lead analytical lab operations, ensuring cGMP compliance and reliable outcomes. Foster team performance, manage client projects efficiently, and provide technical guidance in a dynamic environment...
Reposted 5 days ago
$110K - $130K *
Join our team as a senior leader, tackling advanced chemistry challenges in UV-curable ceramic suspensions. Bridge polymer and ceramic science to innovate formulations and processes that drive next-ge...
1 week ago
$80K - $95K *
Lead the charge in enzyme research and development for bakery innovations, collaborating with cross-functional teams to enhance enzymatic analysis, driving project execution and translating scientific...
6 days ago
Associate Principal Scientist, Downstream Bioprocess Modeling, Digital Insights
$142K - $224K *
Discover transformative solutions as you lead mechanistic modeling efforts that drive decision-making in downstream biologics processes, working closely with teams to enhance productivity and mentor j...
3 days ago
Associate Principal Scientist, Downstream Bioprocess Modeling, Digital Insights
$142K - $224K *
Lead transformative modeling initiatives within biologics processes, utilizing advanced simulation tools to enhance decision-making in downstream processing, while mentoring junior scientists and shap...
3 days ago
Associate Principal Scientist, Downstream Bioprocess Modeling, Digital Insights
$142K - $224K *
Shape impactful outcomes by leveraging mechanistic modeling for downstream biologics processes, guiding decisions on chromatography and operational strategies. Collaborate closely with scientists and...
3 days ago
Associate Principal Scientist, Downstream Bioprocess Modeling, Digital Insights
$142K - $224K *
Drive transformational impact by applying mechanistic modeling and numerical simulation to downstream biologics processes, influencing purification decisions and mentoring team members in a collaborat...
3 days ago
Process Development Sr Scientist ID 35534
$95K - $115K *
Accelerate progress at the forefront of scientific innovation by designing and leading advanced experiments that drive project success and reliability in drug manufacturing processes...
Reposted today
Prin. Scientist, (Director) Regulatory Affairs-CMC
$190K - $300K *
Drive regulatory CMC strategy for pharmaceutical products globally, leading submissions and interactions with agencies while ensuring compliance and fostering team talent. This role ensures successful...
3 days ago
Principal Engineer, Fill and Finish, Technical Operations
$110K - $130K *
Elevate drug product manufacturing by leading engineering strategies in aseptic fill/finish processes. Mentor junior engineers and improve quality through innovation while ensuring compliance with reg...
4 weeks ago
Scientific Leader, Formulation Development-Technical
$83K - $116K *
Accelerate your career by developing and optimizing solid dose formulations. Lead projects through critical NPD milestones while collaborating across teams to ensure timely execution for commercial pr...
Reposted 3 weeks ago
Director Analytical Research and Development
$135K - $160K *
Lead a high-performing analytical R&D team, coordinating cross-functional efforts to deliver innovative solutions while ensuring compliance with industry standards and fostering a collaborative enviro...
Reposted 3 weeks ago
Senior Formulation Scientist I
$95K - $115K *
Advance your career by designing cutting-edge formulations for drug products, focusing on innovation and optimization from pre-formulation through to manufacturing, while collaborating with cross-func...
3 weeks ago
$88K - $105K *
Join a team that's dedicated to optimizing laboratory operations while ensuring compliance with regulations. Manage staff, equipment, and resources to drive quality results and support preclinical stu...
2 weeks ago
$88K - $105K *
Transform laboratory operations by ensuring compliance with SOPs and GLP. Manage resources, train staff, and improve efficiencies, while collaborating on long-term objectives. Drive quality results fo...
2 weeks ago
Senior Scientist, Target Discovery & Biology - Functional Genomics
$123K - $166K *
Lead the charge in innovative target discovery by employing functional genomics in complex biological systems, driving impactful projects from inception to validation within a collaborative research e...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.