Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$100K - $275K *

Accelerate project success by leading complex programs in defense technology. Oversee full lifecycle management, ensuring alignment with cost, schedule, and performance targets while developing strong...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $275K *

Lead the charge in program management for complex defense projects, overseeing all lifecycle phases to ensure strategic success. Collaborate with diverse teams, engage with customers, and innovate for...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $275K *

Oversee the execution of complex projects for cutting-edge ICBM technologies, ensuring cost, schedule, and performance targets are met while fostering strong customer relationships and leading high-pe...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $161K *

Innovate by developing and optimizing sample preparation methods for advanced proteomic applications, ensuring quality and scalability in a collaborative lab environment. Engage with diverse biologica...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $166K *

Drive innovation in advanced radar systems by leveraging software development skills. Collaborate with a diverse team of scientists and engineers to analyze and enhance system performance using cuttin...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$85K - $95K *

Join a team that's advancing bioproduction technologies by executing critical upstream bioprocess operations to ensure successful scale-up from synthetic design to large-scale protein production...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $90K *

Elevate project management skills by coordinating environmental lab projects, fostering client relationships, and ensuring accuracy while navigating complex scientific processes to deliver exceptional...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $275K *

Empower HR success by leading Workday HCM initiatives, integrating solutions, and enhancing user experience. Drive effective reporting and optimize system performance through strategic collaboration w...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$117K - $184K *

Join our team as a Senior Scientist to advance digital modeling strategies in drug substance and product manufacturing. Utilize CFD and data-driven approaches to optimize processes and drive innovatio...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Join the R&D team to pioneer innovative polymer solutions for high-performance concrete applications, contributing to advanced, sustainable cementitious systems while collaborating across technical an...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$87K - $107K *

Lead materials and process development initiatives for innovative wipes technology, guiding projects from conception through commercialization, while collaborating with global teams to optimize nonwov...

Reposted yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $180K *

Advance your career by developing innovative computational approaches to explore protein evolution. Collaborate within a team to analyze data across non-model clades, contributing to the understanding...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Join a dynamic team, driving innovative analyses in CAR T therapy development to enhance treatment solutions for pediatric brain malignancies, while overseeing method optimization and supporting cross...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $130K *

Research transformative protein immunotherapy solutions as part of an interdisciplinary team. Drive innovative approaches from concept to clinical trials, engaging in next-gen antibody development and...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $181K *

Deliver innovative materials solutions by conducting advanced lab experiments and interfacing with sponsors to tackle critical technical challenges. Contribute to interdisciplinary research while driv...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Join a team that drives innovation by enhancing purification chemistry and processes from lab scale to full commercialization, leading cross-disciplinary teams to achieve quality and efficiency in GMP...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leading the mechanical design of innovative systems, ensuring effective collaboration across disciplines while managing vendor relationships and guiding product development from pr...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead clinical trial operations ensuring compliance with regulations and GCP guidelines. Drive quality assurance initiatives and mentor teams, while overseeing audits, training, and CAPA processes to u...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $192K *

Engage in cutting-edge antibody engineering to drive the development of novel therapeutics. Leverage your expertise in molecular biology and protein characterization while collaborating with multidisc...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $138K *

Champion the advancement of oligonucleotide therapeutics by performing critical analytical chemistry to ensure quality control and method development for innovative synthetic oligonucleotides, directl...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Drive advancements in small molecule drug discovery by applying cutting-edge machine learning techniques, collaborating closely with multidisciplinary teams to facilitate strategic decisions and optim...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$103K - $134K *

Build a bright future in oligonucleotide synthesis by enhancing process efficiency and integrity. Collaborate in a dynamic team to develop robust manufacturing processes that impact therapeutics and i...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $210K *

Transform therapeutic development by leading the design of innovative antibody-oligonucleotide conjugation technologies. Drive cross-functional collaboration and mentor a diverse team to accelerate br...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Pioneer a transformative role in laboratory operations, managing resources, budgets, and compliance to ensure high-quality performance. Lead strategic initiatives while collaborating across teams to s...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$131K - $177K *

Partner with us to drive high-throughput binder discovery and lead experimental validation of computationally designed proteins. You’ll create scalable libraries, characterizing innovative tool molecu...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.