Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$268K - $358K *

Pioneer groundbreaking domain models connecting biological data with machine learning, utilizing innovative methodologies to interpret complex biological interactions and guide experimental strategies...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $129K *

Transform chemical regulatory practices by managing project deliverables, collaborating with teams, and providing regulatory expertise for diverse clientele while ensuring compliance with environmenta...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $162K *

Advance your career by tackling complex engineering challenges in DNA sequencing. In this collaborative research role, you'll design, fabricate, test, and optimize innovative systems that drive techno...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Architect innovative AI solutions bridging research and healthcare. You'll design experiments, evaluate AI models, and collaborate with teams to drive impactful product development for health-focused...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to empower the future of AI in healthcare through innovative experiments, model evaluations, and collaborative research, driving impactful solutions for clinical environments and p...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $200K *

Drive engineering projects from inception to completion while managing complex systems within a cross-functional team. Ensure project milestones and deliverables meet strategic objectives while adheri...

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$170K - $200K *

Drive the launch of innovative software products by collaborating with teams to conduct market research, develop roadmaps, and manage product life cycles while ensuring user-centric value and effectiv...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform upstream bioprocessing through innovative design and execution, focusing on mammalian cell culture for recombinant protein and viral antigen production while optimizing processes for cost-ef...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $181K *

Join a team that's pushing the boundaries of protein engineering by developing innovative platform technologies. This role calls for a Senior Scientist to design and test large variant libraries, infl...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Join a team that's advancing diabetes research by leading innovative drug discovery efforts and establishing in vitro assays to evaluate new therapeutic targets, while collaborating with a global team...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading high-throughput antibody discovery and development in a collaborative environment. Utilize advanced techniques in protein biochemistry, automation, and molecular biology, w...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$146K - $189K *

Drive the development and assessment of single-use disposable materials in collaboration with cross-functional teams. Serve as an expert in material compatibility, lead risk assessments, and innovate...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$118K - $182K *

Champion the seamless execution of automated lab workflows, ensuring operational excellence and quality while leading a dedicated team in a fast-paced research environment. Your leadership will drive...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $140K *

Lead drug discovery initiatives by executing diverse biological and bioanalytical assays. Collaborate effectively within a dynamic team to advance therapeutic development, impacting cellular rejuvenat...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Elevate your career by leading the development of innovative omics platforms, driving therapeutic discovery through spatial and functional genomics. Collaborate across teams to transform complex data...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Unlock innovative opportunities as a Principal Scientist in Multiomics, driving advancements in spatial omics and functional genomics to influence therapeutic discovery. Collaborate with teams and lea...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $134K *

Drive scientific support excellence by managing team performance, enhancing customer interactions, and implementing best practices to improve support operations and deliver exceptional service across...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in advanced clinical research by designing and executing complex studies, leveraging your expertise to foster innovation and collaboration across departments to propel the development...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $125K *

Contribute to the development of innovative surface chemistry products for next-generation sequencing. Collaborate across teams to translate research into manufacturable solutions while executing expe...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $116K *

Empower teams to conduct in-depth technical investigations, ensuring compliance with regulatory standards. Drive continuous improvement in quality and efficacy for sterile compounding, while fostering...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $105K *

Deliver comprehensive LC-MS analyses by developing and validating bioanalytical methods while ensuring GLP compliance. Collaborate effectively with cross-functional teams to meet client needs and main...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $105K *

Develop and validate bioanalytical LC-MS methods, interact with clients, and analyze samples while ensuring compliance with GLP and other regulatory guidelines in a collaborative lab environment...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Join us in advancing innovative products as a Research Scientist, tackling technical challenges in R&D. You will drive projects from ideation to commercialization and collaborate in a multi-disciplina...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $120K *

Join a team that's driving innovation in R&D, focusing on product development and technical problem-solving. Collaborate across disciplines to develop groundbreaking solutions and improve existing for...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$114K - $234K *

Take ownership of complex AI evaluation projects, turning user needs into measurable hypotheses, conducting experiments, and delivering actionable insights that guide product development in cutting-ed...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.