Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$175K - $200K *

Join a team that's redefining protein sequencing by leading product development for innovative reagents and workflows. Shape technical strategy, guide cross-functional collaboration, and make a lastin...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to major client projects by driving single-particle cryo-EM processes from sample optimization to structure determination, mentoring junior scientists, and engaging with clients through pre...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$131K - $206K *

Join a team that's advancing Immunology research by profiling therapeutic targets using high-dimensional flow cytometry in a collaborative lab environment, supporting preclinical and clinical program...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Drive innovative cell culture research, optimize stem cell models, and execute experiments with precision. Collaborate in a fast-paced lab environment while promoting efficiency and detail-oriented pr...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Pioneer advancements in geomodelling and AI by driving innovation through research, prototyping, and practical implementation, collaborating across teams to tackle industry challenges and enhance solu...

Calgary, ABIn-Person

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Elevate your career by leading a team of scientists in advancing downstream biologics. Drive strategic initiatives, ensuring regulatory compliance while transforming complex processes across diverse m...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Advance your career by leading a team of scientists in downstream processing for late-stage biologics. Drive innovation, influence manufacturing strategies, and mentor talent while ensuring regulatory...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Create a competitive global product portfolio in molecular diagnostics. Lead strategy, drive growth, and ensure compliance while collaborating with cross-functional teams to enhance product offerings...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $97K *

Engineer innovative solutions within protein engineering, impacting biotherapeutic lead generation through expression, purification, and characterization of antibodies. Collaborate in a dynamic team t...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform cutting-edge research initiatives and lead a multidisciplinary team while developing innovative materials and processes. Drive technical programs that support long-term growth in a dynamic...

Kingston, ONIn-Person

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$230K - $345K *

Empower innovation and leadership as you drive the strategic direction of the SSAE Group, enhancing drug substance and product development while mentoring top talent in a dynamic global environment...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Partner with us to drive growth in environmental and materials science across the Americas. Lead strategic initiatives, collaborate with teams, and champion market trends to achieve revenue goals and...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$268K - $358K *

Pioneer groundbreaking domain models connecting biological data with machine learning, utilizing innovative methodologies to interpret complex biological interactions and guide experimental strategies...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $129K *

Transform chemical regulatory practices by managing project deliverables, collaborating with teams, and providing regulatory expertise for diverse clientele while ensuring compliance with environmenta...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $162K *

Advance your career by tackling complex engineering challenges in DNA sequencing. In this collaborative research role, you'll design, fabricate, test, and optimize innovative systems that drive techno...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Architect innovative AI solutions bridging research and healthcare. You'll design experiments, evaluate AI models, and collaborate with teams to drive impactful product development for health-focused...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to empower the future of AI in healthcare through innovative experiments, model evaluations, and collaborative research, driving impactful solutions for clinical environments and p...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $200K *

Drive engineering projects from inception to completion while managing complex systems within a cross-functional team. Ensure project milestones and deliverables meet strategic objectives while adheri...

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$170K - $200K *

Drive the launch of innovative software products by collaborating with teams to conduct market research, develop roadmaps, and manage product life cycles while ensuring user-centric value and effectiv...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform upstream bioprocessing through innovative design and execution, focusing on mammalian cell culture for recombinant protein and viral antigen production while optimizing processes for cost-ef...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $181K *

Join a team that's pushing the boundaries of protein engineering by developing innovative platform technologies. This role calls for a Senior Scientist to design and test large variant libraries, infl...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $230K *

Join a team that's advancing diabetes research by leading innovative drug discovery efforts and establishing in vitro assays to evaluate new therapeutic targets, while collaborating with a global team...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading high-throughput antibody discovery and development in a collaborative environment. Utilize advanced techniques in protein biochemistry, automation, and molecular biology, w...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$146K - $189K *

Drive the development and assessment of single-use disposable materials in collaboration with cross-functional teams. Serve as an expert in material compatibility, lead risk assessments, and innovate...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$118K - $182K *

Champion the seamless execution of automated lab workflows, ensuring operational excellence and quality while leading a dedicated team in a fast-paced research environment. Your leadership will drive...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.