Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$200K - $250K *

Champion the strategic direction of project controls, ensuring operational excellence and client satisfaction. Drive innovation while mentoring high-potential consultants to build a sustainable, high...

2 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Lead a dynamic consulting practice, driving strategic growth and operational excellence while delivering high-value results to clients. Inspire innovation, ensure service quality, and develop future l...

2 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Lead the charge in strategic growth and operational excellence within the consulting practice, driving innovation and delivery quality, while mentoring talent to shape a sustainable future in the life...

2 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Accelerate progress at the forefront of project controls, driving strategic direction and operational excellence within a consulting practice. Lead innovative service development, enhance quality, and...

2 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$69K - $146K *

Drive the future of quality control by leading advanced analytical testing, guiding junior scientists, and ensuring compliance with GMP standards. Play a crucial role in method validation, investigati...

Scarborough, ONIn-Person

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Unlock potential by developing and executing sophisticated assays, evaluating compounds, and driving target biology in a fast-paced environment focused on oncology drug discovery and therapeutic innov...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$89K - $139K *

Champion the development of innovative medical isotope products by leading R&D projects, collaborating with cross-functional teams, and ensuring compliance with industry standards to successfully brin...

Ottawa, ONIn-Person

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$127K - $180K *

Innovate in in vivo pharmacology by leading studies in cancer biology and immuno-oncology. Utilize advanced models to assess drug efficacy, collaborate on research projects, and ensure compliance with...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$65K - $121K *

Lead the charge in preclinical imaging studies, supporting research through hands-on animal model work and team leadership. Drive project execution and enhance laboratory operations in a dynamic resea...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$76K - $99K *

Innovate within our R&D team by leading research efforts to commercialize new ideas. Collaborate with peers to drive product development and growth strategies while ensuring alignment with company obj...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K - $266K *

Drive innovative cell culture media development and metabolomics research, leading to optimized processes for next-gen therapies. Collaborate across teams to translate scientific expertise into strate...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $266K *

Lead cutting-edge metabolomics research to optimize cell culture media platforms, collaborating with cross-functional teams to drive innovations in cell therapy and improve manufacturing processes, wh...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $158K *

Join the Stability team to drive analysis of siRNA drug substance stability, ensuring lifecycle management and regulatory submissions while fostering collaboration across departments for effective dat...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

The Senior Scientist, Process Development will execute cell culture experiments and downstream processing while contributing to process development projects. This hands-on lab-based position requires...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Drive innovation by developing and optimizing manufacturing processes for HPAPIs, ensuring compliance with regulatory standards while collaborating with clients and cross-functional teams to achieve p...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$124K - $265K *

Champion innovative analytical solutions for drug development, engaging in method design and execution across diverse molecular types. Collaborate cross-functionally to influence pipeline decisions an...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$163K - $209K *

Elevate operational efficiency by managing laboratory, budget, and team functions. Collaborate across scientific teams to streamline processes and drive excellence in drug discovery and development wi...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $193K *

Drive small molecule process development for late-stage drug products, overseeing technical execution from Phase 3 to PPQ at internal/external sites. Collaborate broadly across teams to ensure success...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $238K *

Champion innovative RAS(ON) inhibitor programs by providing strategic leadership and scientific expertise. Mentor a talented team, drive impactful studies, and collaborate with cross-functional teams...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$159K - $207K *

Champion upstream technical activities in biologics, overseeing commercial process development to ensure robust, compliant manufacturing and support lifecycle improvements across multiple sites...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Lead the advancement of analytical methods for biopharmaceuticals, collaborating with teams to ensure quality and regulatory compliance. Drive innovation and mentor junior scientists, fostering a high...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $94K *

Elevate analytical excellence by leading method development for active pharmaceutical ingredients, ensuring compliance with industry guidelines and driving innovation in an R&D environment...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a team that's committed to environmental excellence, overseeing multidisciplinary projects and leading junior staff. Drive business development while ensuring compliance and delivering impactful...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

$130K - $180K *

Join us as a key leader in driving the commercial strategy for scientific solutions while developing a high-performance team that engages top-tier clients in the life sciences sector. Own flagship acc...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Shape the future of scientific solutions by leading a high-performing team, engaging key clients, and defining commercial strategies to drive growth and innovation in life sciences through advanced da...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.