Principal Scientist Jobs in South San Francisco, CA

Join a team that's shaping the future of health by leading innovative therapeutic programs from concept to validation, ensuring scientific rigor and strategic execution while driving meaningful advanc...

Shape the future of AI by leading advanced research in machine learning, focusing on large language models, optimization, and scalable training systems. Collaborate with talented teams, publish impact...

Lead the charge in providing strategic regulatory expertise in food safety and nutrition, mentoring teams, and driving business growth by enhancing client relationships while tackling complex scientif...

Optimize safety assessments across drug development for multiple programs while integrating cross-functional scientific insights to enhance portfolio strategies and risk management decisions...

Innovate in mechanistic modeling and experimental design to enhance bioinformatics systems. Contribute to the development of evaluations and analyses that integrate biological data with deep learning...

Lead and optimize synthetic execution for small-molecule and peptide therapeutic programs, transforming target structures into test-ready compounds through expert chemistry methodologies and workflows...

Lead AI-driven protein therapeutic discovery, providing scientific strategy and technical leadership, while mentoring staff and driving experimental design and optimization for impactful therapeutic s...

Join a team that's pioneering research in AI model interpretability. Collaborate with a mission-driven group to advance practical tools and techniques while fostering a culture of innovation and owner...

Lead the charge in peptide design and synthesis, managing workflows from sequence selection to biological handoff, while troubleshooting complex chemistry and analytical challenges to drive high-quali...

Drive analytical method development for biologics and vaccines, using advanced techniques. Lead method optimization and troubleshooting, mentor junior scientists, and ensure compliance through quality...

Shape the future of immunology research by driving program strategy and advancing therapeutic targets through innovative experimentation and collaborative insights. Engage with leadership and mentor j...

Champion groundbreaking in vivo CRISPR screening initiatives and lead innovative genetic research projects that drive therapeutic discoveries through high-throughput functional genomics and advanced t...

Unlock the potential of drug discovery by leading medicinal chemistry initiatives, from compound design to purification, while collaborating closely with biology teams to enhance therapeutic efficacy...

Advance biomolecular characterization by pioneering antibody-target binding techniques, leveraging expertise in BLI and SPR with a collaborative team focused on innovative research and impactful disco...

Drive the analytical development and biophysical characterization of biologics. Collaborate across teams to evaluate therapeutic candidates and establish strategic testing methodologies. Lead technica...

Join a team that's driving innovative drug discovery through advanced structural biology. Lead interdisciplinary projects, utilize cutting-edge techniques, and mentor peers in a collaborative environm...

Engineer breakthroughs in early drug discovery by leveraging computational biology expertise to innovate experimental systems and collaborate with cross-functional teams for impactful research efforts...

Pioneer groundbreaking research initiatives aimed at enhancing alignment methodologies. Collaborate with a cross-functional team, driving empirical and theoretical studies while contributing to signif...

Contribute to groundbreaking research on alignment problems, leveraging both empirical and theoretical methods, while collaborating with interdisciplinary teams and advancing scientific understanding...

Advance therapeutic discovery by leading analytical frameworks for in vivo perturbation data, driving target prioritization, and collaborating with disease experts to enhance translational efficacy ac...

Contribute to comprehensive safety strategies across drug development, leading toxicology assessments and guiding decision-making processes. Collaborate with cross-functional teams to manage safety li...

Advance your career by leading the Oligonucleotide & Small Molecule CMC Analytical Development team. Provide hands-on scientific leadership in method development, testing, and regulatory documentation...

Launch innovative analytical methods to support diverse fermentation processes, ensuring operational excellence in a cutting-edge pilot plant environment while collaborating with cross-functional team...

Transform safety assessment in drug development by leading innovative preclinical strategies in Neuroscience and CVRM portfolios. Collaborate cross-functionally and drive strategic initiatives to addr...

Drive innovative downstream purification processes for commercial biologics, ensuring technical alignment across manufacturing sites while supporting lifecycle management and regulatory updates for la...