Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$156K - $190K *
Drive innovation as a technical leader in R&D, focusing on dental chemical consumables. Lead complex experiments, mentor junior scientists, and ensure product excellence while adhering to quality stan...
1 month ago
$90K - $130K *
Join a team that's driving innovation in molecular and cell biology by developing and executing advanced cell-based assays, optimizing protocols, and collaborating cross-functionally to advance high-i...
2 days ago
Principal Scientist, Analytical Sciences
$160K - $190K *
Join a team that's shaping the future of analytical science for synthetic oligonucleotide therapies. Manage CMO labs, develop methods, and ensure compliance for drug substances throughout development...
3 weeks ago
Senior Scientist / Principal Scientist, Bioprocess Sciences
$120K - $198K *
Drive bioprocess development for bacterial protein production, overseeing scale-up strategies and external partnerships. Collaborate cross-functionally to optimize purification processes in a dynamic...
3 weeks ago
$131K - $196K *
Deliver innovative oligonucleotide solutions while leading product development and technical projects. Collaborate in a hands-on lab environment, empowering teams through mentorship and driving excell...
2 days ago
Principal Scientist-Analytical Research & Development (ARD)
$140K - $155K *
Engage in the development and implementation of analytical methods for APIs, ensuring compliance with industry standards. Collaborate with project teams while applying advanced techniques and leading...
2 weeks ago
$100K - $130K *
Elevate your scientific career by leading innovative LCMS initiatives, defining analytical strategies, and delivering impactful results within the pharmaceutical industry while mentoring emerging scie...
Reposted today
Senior Scientist I, Product Development
$150K - $165K *
Transform product development by leading QC method innovation, optimizing processes, and ensuring robust assay transfer from R&D to manufacturing. Collaborate across teams to drive success in bringing...
2 weeks ago
Principal Scientist 1 - Chemical Research & Development
$100K - $130K *
Empower innovative chemical synthesis and development by optimizing existing routes and designing new methodologies. Collaborate with teams to ensure safe, efficient lab operations while leading proje...
2 weeks ago
Supervising Principal Scientist, Process Development
$90K - $210K *
Reimagine the future of cell therapy as an innovative leader driving process development and optimization. Collaborate across teams and external partners to enhance the Cellares platform while mentori...
2 weeks ago
Senior Scientist, Bioanalytical Science
$133K - $157K *
Join a dynamic team to advance preclinical discovery in bioanalytical sciences, optimizing methods and managing studies, while fostering a culture of innovation aimed at improving mental health soluti...
1 week ago
Principal Scientist: ARD Compliance Lead
$106K - $176K *
Advance compliance and data integrity in ARD through cross-functional collaboration. Drive continuous improvement and uphold quality standards while effectively managing GMP processes and team initiat...
2 weeks ago
Principal Scientist - Process Development, Upstream
$100K - $130K *
Lead the charge in advancing upstream processing methodologies for mammalian cell culture, facilitating successful tech transfer to cGMP manufacturing while managing multiple projects and driving inno...
1 week ago
$120K - $140K *
Unlock potential by leading applied bacteriology programs to enhance global health through innovative research and collaboration. Drive product development and ensure compliance while mentoring future...
2 weeks ago
Principal Scientist, Analytical Development
$130K - $179K *
Lead the charge in advancing analytical development for drug substance projects, from preclinical to commercial phases. Collaborate with cross-functional teams to optimize methods and ensure complianc...
4 weeks ago
Principal Scientist, Product & Process Technology
$100K - $130K *
Drive technical transfer and process optimization for Oral Solid and Liquid products, ensuring compliance, efficiency, and safety. Collaborate with R&D and manufacturing teams to resolve issues and su...
1 week ago
Principal Scientist, Large Molecules Mass Spectrometry
$65K - $193K *
Lead bioanalytical studies using mass spectrometry to assess therapeutic proteins' ADME properties and mentor a diverse team towards innovative research milestones...
Yesterday
Senior Scientist, Bioanalytics
$100K - $130K *
Join a team that's dedicated to enhancing quality through data analysis and technical leadership, driving innovation in bioanalytical methods to support global health initiatives and improve product s...
2 weeks ago
$90K - $120K *
Join a team that’s committed to driving agricultural innovation by conducting impactful research in plant nematology, enhancing crop resistance, and collaborating across disciplines to support farmers...
2 weeks ago
Senior Scientist - Process Development
$150K - $160K *
Join us to lead a team in developing innovative cell processing methods, enhancing T-cell biology understanding, and driving project success through collaboration and scientific expertise...
3 days ago
$90K - $120K *
Empower innovation in coatings by providing technical support to distributors and customers. Engage in laboratory projects, optimize resources, and grow market presence in Transportation and Plastics...
4 weeks ago
Senior Scientist, Fermentation - IR&D, Product Development
$120K - $150K *
Champion innovation in upstream fermentation development, driving collaboration across teams to optimize processes for novel vectors. Utilize advanced technologies to enhance product solutions and sup...
1 week ago
Principal Scientist, Analytical Sciences
$71K - $187K *
Execute innovative analytical methods to characterize RNA therapeutics and support development efforts. Collaborate with cross-functional teams in a fast-paced environment to enhance analytical capabi...
Yesterday
Principal Scientist, Bioreactor Process Design
$154K - $174K *
Drive innovation in bioreactor process development, leading diverse teams to create cutting-edge biotherapeutics manufacturing processes while collaborating across functions and pushing scientific bou...
Reposted 3 weeks ago
Research Scientist, Special Projects
$136K - $184K *
Help us innovate by developing groundbreaking consumer products and collaborating across teams. Engage in both academic and applied research, fostering creativity and focus to accelerate product deliv...
Reposted 2 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.