Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist Algorithm Lead
$151K - $261K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
3 days ago
Senior Principal Scientist, Drug Substance
$175K - $230K *
Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...
1 week ago
Senior Principal, AI Product Owner - Agentic AI
$175K - $230K *
Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...
3 days ago
Senior Principal, AI Product Owner - LLMs
$175K - $230K *
Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...
3 days ago
$125K - $224K *
Contribute to groundbreaking research by enhancing atmospheric radiative transfer models, collaborating with a team of experts, and driving innovation in numerical methods within the scientific commun...
1 week ago
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
$171K - $214K *
Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...
1 week ago
Senior Principal, AI Product Owner - Machine Learning
$175K - $230K *
Drive your career with innovative AI and machine learning products that enhance global supply chain efficiency. Own strategy, elevate data standards, lead governance, and foster collaboration in a sen...
Yesterday
$120K - $150K *
Transform the future of drug development by leading innovative simulation projects, acting as a scientific liaison between clients and teams, and driving advances in pharmacometrics with your expertis...
Today
$100K - $130K *
Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...
2 weeks ago
$120K - $135K *
Advance your career by leading complex AI and IT projects. This high-visibility role entails managing cross-functional teams and driving accountability across multiple workstreams, ensuring successful...
1 week ago
Staff Scientist, Imaging Systems
$234K - $271K *
Lead the charge in developing cutting-edge AI and image processing solutions for cardiac imaging, translating clinical needs into innovative algorithms while collaborating across functions to enhance...
4 days ago
Director, PF Project Delivery - Project Farma
$150K - $170K *
Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...
Reposted 2 weeks ago
$165K - $206K *
Lead the charge in transforming complex data into actionable insights, partnering with stakeholders to measure and optimize commercial strategies, and architecting large datasets to influence critical...
4 weeks ago
Senior Principal Architect, AI
$173K - $277K *
Innovate within the AI Center of Excellence to architect and govern advanced AI solutions, shaping how AI is designed, deployed, and scaled across all engineering projects with a commitment to excelle...
3 days ago
$152K - $190K *
Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...
Reposted 1 week ago
Senior Director of Program Management, Global Operations
$150K - $180K *
Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...
Reposted 3 weeks ago
$90K - $120K *
Advance pharmaceutical marketing analytics by leading insight delivery and measurement strategies. Oversee KPI frameworks, reporting processes, and data visualization to ensure compelling insights tha...
3 days ago
$100K - $130K *
Join a team that's leading innovative Cost Improvement Projects in medical devices. You'll manage engineering efforts, ensuring compliance while driving change and collaboration across cross-functiona...
3 weeks ago
$130K - $180K *
Join a dynamic team to lead product strategy connecting tech investments to business outcomes, enhancing operational success, and driving innovation while fostering collaboration and developing high-p...
Today
$66K - $99K *
Champion environmental project success through management of assessments, remediation, and stakeholder communications while mentoring junior staff and ensuring compliance with regulations and timeline...
Today
Manager - Global Laboratory Services
$90K - $120K *
Lead strategic governance and performance oversight across global laboratory networks, fostering effective partnerships and ensuring compliance to enhance service delivery and business success. Drive...
2 days ago
$150K - $200K *
Drive the advancement of our predictive toxicology platform. Collaborate cross-functionally to shape scientific vision, develop innovative modeling techniques, and oversee execution. Lead a diverse te...
Reposted yesterday
$90K *
Take ownership of project operations, ensuring quality execution and client satisfaction through effective management of timelines, budgets, stakeholder relationships, and study logistics while leadin...
Yesterday
Senior Project Manager, Oncology
$122K *
Champion project success by leading the global team in Oncology, ensuring adherence to budgets, timelines, and quality standards while fostering client relationships and supporting business developmen...
Reposted 3 weeks ago
Senior Scientist, Global Regulatory Lead
$118K - $197K *
Shape the future of animal health by leading regulatory strategies for innovative veterinary products. Collaborate globally, engage with regulatory agencies, and drive project success through expert n...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.