Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$200K - $257K *

Join a team that's shaping the future of mental health care by providing exceptional psychiatric services to children and adolescents. Enjoy a flexible hybrid schedule while making a meaningful impact...

Today

  •   Less than 5 years exp.  •   Healthcare

$150K *

Drive new business growth by owning the full sales cycle in SMB and Mid-Market segments. Build relationships, strategize territory plans, and deliver compelling proposals to meet client needs while ex...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $300K *

Lead the charge in transforming cardiovascular care. Oversee clinical teams, ensuring high standards, build partnerships, and shape value-based care strategies to improve patient outcomes and provider...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's designing cutting-edge systems for diverse applications. You'll engage in analog, digital, and mixed-signal design, ensuring your innovations are tested and ready for real-world cha...

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$118K - $177K *

Join a team that's improving life sciences by delivering strategic insights across diverse projects. Lead analysis, mentor junior staff, and create impactful client materials while working on multiple...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $110K *

Transform user experiences by designing innovative products from concept to production. Collaborate with a dynamic team to create functional, aesthetically pleasing designs that resonate with our bran...

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Transform customer IT service requirements into innovative solutions that enhance loyalty and profitability. Lead technical resources in delivering high-quality financial industry solutions while ensu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$104K - $120K *

Unlock your potential as an SLP providing remote speech therapy. Collaborate with educators, develop IEPs, and support student success in a flexible environment tailored for diverse learning needs...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $175K *

Support clients by analyzing technology risk landscapes and delivering tailored solutions. Collaborate with teams on audits, assessments, and innovative AI-enabled strategies to enhance operational ex...

Today

  •   Less than 5 years exp.  •   Business Services

$174K - $374K *

Engage with patients in their homes to conduct health evaluations, build relationships, and bridge care gaps. This role demands extensive travel and flexibility to provide personalized care and diagno...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $175K *

Develop and lead clinical science activities for assigned studies, ensuring cross-functional collaboration and timely issue resolution. Drive protocol development, data review, and regulatory input wh...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Join a team that's transforming clinical trials through advanced data science. Drive the development of predictive models and machine learning algorithms to enhance patient enrollment and trial manage...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $164K *

Champion comprehensive patient care through clinical coordination, treatment supervision, and effective communication with patients and specialists. Drive departmental efficiency while managing acute...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Manage IT projects to implement M365 solutions for diverse clients, ensuring successful execution of project goals and fostering collaboration between teams...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the charge in architectural design and documentation for complex projects. Collaborate with multidisciplinary teams to deliver high-quality solutions from concept to construction, ensuring techni...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$135K - $160K *

Lead the management of privacy risks and regulatory compliance while providing expert guidance on AI-related legal issues to cross-functional teams in a dynamic healthcare environment. Drive privacy i...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $165K *

Lead the charge in managing pharmacy operations, ensuring compliance, overseeing staff, and delivering exceptional patient care in a collaborative environment. Drive innovation while handling purchasi...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $132K *

Champion the future of clinical documentation education by developing and implementing training for healthcare providers. Collaborate with teams to enhance quality metrics and ensure compliance with d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $481K *

Take ownership of strategic growth and business development, driving P&L accountability and commercial success. Lead cross-functional teams to enhance revenue pipelines, forge key alliances, and ensur...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $230K *

Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $153K *

Accelerate progress at the intersection of product management and engineering, leading the development of shared platform capabilities that enhance product solutions across the organization, ensuring...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$144K - $240K *

Transform complex operational software by leading user experience research, designing critical interfaces, and seamlessly collaborating with engineers to enhance automation in demanding environments...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive healthcare transformation by leading advanced consulting initiatives, enhancing delivery systems, and improving health outcomes. Collaborate with clients and stakeholders to implement strategic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$128K - $176K *

Transform complex clinical and regulatory documents into clear, compliant submissions. Collaborate with teams to ensure accuracy and adherence to standards while managing multiple projects in a fast-p...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.