Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$199K - $252K *

Manage strategic operations and communication, enhancing team cohesion and decision-making within a dynamic R&D environment. Partner with leadership to drive operational effectiveness and culture, max...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$89K - $155K *

Join us to connect with medical professionals, delivering clinical insights and driving product utilization. As a key customer liaison, you'll implement marketing strategies and foster relationships t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $180K *

Accelerate procurement excellence by leading high-impact customer engagements, driving strategic initiatives, and fostering a culture of continuous improvement within a dynamic team environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$150K - $170K *

Support our Legal team by managing the contract lifecycle, drafting agreements, and ensuring compliance. Collaborate with the Supply team to enhance contracting processes and infrastructure in a fast...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Drive scientific engagement as a Senior Medical Science Liaison, fostering relationships with Key Opinion Leaders and healthcare professionals. Leverage your expertise in cardiovascular disease to sup...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Help us enhance federal human capital operations through independent analysis, strategic recommendations, and effective program delivery. Collaborate on data-driven insights to improve efficiency and...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $220K *

Drive your career by leading a global trade compliance program, ensuring adherence to international regulations while enhancing governance and operational efficiency across a complex business landscap...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$67K - $182K *

Lead the charge in driving operational excellence and strategic direction for a high-performing underwriting team, ensuring quality Medicare underwriting services that support profitable growth and bu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$190K - $210K *

Advance business growth by developing and executing sales strategies in the Plasmid DNA and Viral Vector markets, while fostering strong client relationships and driving revenue through a client-cente...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Grow your career by developing and maintaining key customer relationships, driving sales success, and collaborating with teams to exceed goals. Leverage your expertise in account management and sales...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$230K - $243K *

Champion customer success by leading a dynamic team to drive post-live growth, retention, and expansion initiatives within enterprise software, influencing retailer P&L outcomes and ensuring a consult...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform healthcare processes by leading quality improvement initiatives. Utilize lean, six sigma, and change management expertise to enhance operational excellence, patient satisfaction, and efficie...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion operational excellence at a high-volume distribution center, leading multi-shift teams in fulfillment, inventory management, and automation initiatives while driving continuous improvement an...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$74K - $119K *

Transform healthcare delivery by coordinating strategic programs that enhance clinical and operational excellence. Collaborate with diverse teams to implement innovative solutions, ensuring compliance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $300K *

Drive product strategy and lifecycle management, ensuring alignment with market needs and business growth. Lead cross-functional teams to develop, launch, and support innovative medical devices while...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $290K *

Champion growth by developing best-in-class business practices, leading a high-performing new business team, managing pipeline opportunities, and fostering strategic partnerships with leadership to dr...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$222K - $278K *

Empower businesses by eliminating supply chain blind spots. Drive adoption of our innovative Tracking Label product, collaborating with Enterprise teams to enhance shipment visibility and security acr...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$113K - $226K *

Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Innovate your career by building agile marketing systems that leverage AI and data. Own the demand generation engine, connecting audience insights and multi-channel campaigns to drive measurable growt...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$198K - $230K *

Join a team that's shaping the future of commercial execution by integrating strategies across channels and customers to drive sustainable growth and measurable outcomes in a dynamic, collaborative en...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.